ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	159/884	423/7206	8.17684352655e-44
ko04724	Glutamatergic synapse	75/884	152/7206	9.85401569258e-30
ko05033	Nicotine addiction	42/884	56/7206	2.35556275428e-27
ko04728	Dopaminergic synapse	71/884	185/7206	3.44507513104e-20
ko05032	Morphine addiction	52/884	110/7206	7.8403677085e-20
ko04713	Circadian entrainment	57/884	136/7206	1.59038776692e-18
ko04727	GABAergic synapse	50/884	110/7206	3.36077015114e-18
ko04723	Retrograde endocannabinoid signaling	63/884	175/7206	2.04099797305e-16
ko04725	Cholinergic synapse	59/884	160/7206	5.31555837866e-16
ko04721	Synaptic vesicle cycle	39/884	80/7206	9.57186817585e-16
ko04726	Serotonergic synapse	50/884	137/7206	1.55174301242e-13
ko04024	cAMP signaling pathway	79/884	279/7206	2.0347192241e-13
ko04020	Calcium signaling pathway	76/884	265/7206	2.31377261495e-13
ko04911	Insulin secretion	45/884	117/7206	3.00037632416e-13
ko04921	Oxytocin signaling pathway	62/884	209/7206	8.8508803229e-12
ko04720	Long-term potentiation	36/884	99/7206	4.72334404879e-10
ko05031	Amphetamine addiction	34/884	91/7206	6.25994340327e-10
ko04742	Taste transduction	26/884	61/7206	2.48713395213e-09
ko04261	Adrenergic signaling in cardiomyocytes	55/884	205/7206	8.15663742664e-09
ko03040	Spliceosome	1/884	145/7206	2.34725738617e-07
ko04010	MAPK signaling pathway	70/884	321/7206	8.2349781628e-07
ko04744	Phototransduction	16/884	36/7206	1.54158438354e-06
ko04925	Aldosterone synthesis and secretion	31/884	105/7206	2.62244490325e-06
ko05030	Cocaine addiction	24/884	73/7206	3.10700182331e-06
ko04730	Long-term depression	25/884	78/7206	3.27844997467e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	24/884	74/7206	4.0732973193e-06
ko05203	Viral carcinogenesis	12/884	277/7206	5.96144628017e-06
ko05164	Influenza A	4/884	167/7206	6.78435148627e-06
ko04070	Phosphatidylinositol signaling system	31/884	112/7206	7.72924092192e-06
ko04970	Salivary secretion	28/884	95/7206	9.09494821431e-06
ko04971	Gastric acid secretion	28/884	98/7206	1.29556235966e-05
ko04514	Cell adhesion molecules (CAMs)	34/884	130/7206	1.70038835159e-05
ko04745	Phototransduction - fly	15/884	38/7206	1.90661425751e-05
ko03013	RNA transport	5/884	166/7206	3.62242034241e-05
ko05322	Systemic lupus erythematosus	4/884	151/7206	4.34437982728e-05
ko05169	Epstein-Barr virus infection	8/884	206/7206	5.21549009442e-05
ko04972	Pancreatic secretion	29/884	111/7206	5.43341005385e-05
ko04072	Phospholipase D signaling pathway	43/884	197/7206	0.000146945916029
ko04120	Ubiquitin mediated proteolysis	4/884	138/7206	0.000186833292142
ko04060	Cytokine-cytokine receptor interaction	8/884	191/7206	0.00018773944197
ko04360	Axon guidance	48/884	233/7206	0.000228769918197
ko04260	Cardiac muscle contraction	25/884	98/7206	0.000268211778219
ko04022	cGMP-PKG signaling pathway	45/884	216/7206	0.000296911557463
ko05168	Herpes simplex infection	8/884	182/7206	0.00035253356454
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/884	79/7206	0.000425140523057
ko04621	NOD-like receptor signaling pathway	6/884	157/7206	0.000473055197566
ko04612	Antigen processing and presentation	1/884	77/7206	0.000741214848624
ko03008	Ribosome biogenesis in eukaryotes	1/884	79/7206	0.000765632528532
ko04141	Protein processing in endoplasmic reticulum	9/884	184/7206	0.000894633751071
ko05162	Measles	4/884	120/7206	0.00106709570781
ko04110	Cell cycle	6/884	145/7206	0.00122254855001
ko04964	Proximal tubule bicarbonate reclamation	10/884	29/7206	0.00163588470017
ko04750	Inflammatory mediator regulation of TRP channels	27/884	122/7206	0.00192841123452
ko04966	Collecting duct acid secretion	9/884	26/7206	0.002700649372
ko04014	Ras signaling pathway	51/884	279/7206	0.00281288554847
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/884	14/7206	0.00420231945805
ko04630	Jak-STAT signaling pathway	6/884	132/7206	0.0044481764082
ko04740	Olfactory transduction	19/884	80/7206	0.00509959375202
ko04146	Peroxisome	3/884	89/7206	0.00544211546486
ko05161	Hepatitis B	10/884	173/7206	0.0065843952424
ko04540	Gap junction	26/884	128/7206	0.00906438074781
ko05110	Vibrio cholerae infection	15/884	63/7206	0.0103988460319
ko04064	NF-kappa B signaling pathway	4/884	96/7206	0.0113600334994
ko04924	Renin secretion	19/884	86/7206	0.0116735446211
ko05414	Dilated cardiomyopathy	23/884	112/7206	0.0125538106748
ko00562	Inositol phosphate metabolism	19/884	89/7206	0.0137437820172
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/884	59/7206	0.014408610044
ko04626	Plant-pathogen interaction	6/884	18/7206	0.0168939339802
ko00590	Arachidonic acid metabolism	1/884	52/7206	0.0174949044041
ko05166	HTLV-I infection	23/884	292/7206	0.0177075490345
ko05130	Pathogenic Escherichia coli infection	3/884	77/7206	0.0216628991393
ko05222	Small cell lung cancer	4/884	89/7206	0.0216691431766
ko04915	Estrogen signaling pathway	25/884	131/7206	0.021719937236
ko00260	Glycine, serine and threonine metabolism	1/884	48/7206	0.0254484369934
ko00240	Pyrimidine metabolism	6/884	110/7206	0.0269446142684
ko04960	Aldosterone-regulated sodium reabsorption	10/884	41/7206	0.0280632623677
ko00330	Arginine and proline metabolism	2/884	61/7206	0.0291281710874
ko04140	Autophagy - animal	11/884	164/7206	0.0292772194347
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/884	182/7206	0.0296529216648
ko05410	Hypertrophic cardiomyopathy (HCM)	20/884	100/7206	0.0297718655506
ko00310	Lysine degradation	3/884	73/7206	0.0300567996338
ko05133	Pertussis	4/884	87/7206	0.0305129800374
ko04212	Longevity regulating pathway - worm	4/884	87/7206	0.0305129800374
ko05140	Leishmaniasis	3/884	75/7206	0.0312355439442
ko05231	Choline metabolism in cancer	25/884	134/7206	0.0321555541312
ko05418	Fluid shear stress and atherosclerosis	12/884	173/7206	0.0336997119156
ko04930	Type II diabetes mellitus	12/884	54/7206	0.0350568206232
ko03022	Basal transcription factors	1/884	44/7206	0.037213392569
ko00071	Fatty acid degradation	1/884	45/7206	0.037554705367
ko00620	Pyruvate metabolism	1/884	46/7206	0.0384894122619
ko03420	Nucleotide excision repair	1/884	46/7206	0.0384894122619
ko03320	PPAR signaling pathway	3/884	69/7206	0.0416727919127
ko05200	Pathways in cancer	46/884	492/7206	0.0458484404645
ko04218	Cellular senescence	13/884	177/7206	0.0476060578303
ko04114	Oocyte meiosis	25/884	139/7206	0.0488362899912
ko04015	Rap1 signaling pathway	45/884	278/7206	0.0496679822637
ko05010	Alzheimer's disease	34/884	202/7206	0.0499802467674