ko pathway ratio_in_study ratio_in_pop p_value ko05032 Morphine addiction 13/121 110/7206 2.95997909465e-08 ko04723 Retrograde endocannabinoid signaling 11/121 175/7206 0.000159377920949 ko04024 cAMP signaling pathway 13/121 279/7206 0.000767367291968 ko00604 Glycosphingolipid biosynthesis - ganglio series 3/121 14/7206 0.00146848538264 ko04360 Axon guidance 11/121 233/7206 0.00177613656365 ko04713 Circadian entrainment 8/121 136/7206 0.00196792157814 ko04740 Olfactory transduction 6/121 80/7206 0.00216126106725 ko04727 GABAergic synapse 7/121 110/7206 0.00241370007746 ko04742 Taste transduction 5/121 61/7206 0.00345263018773 ko04728 Dopaminergic synapse 9/121 185/7206 0.00380602344103 ko04724 Glutamatergic synapse 8/121 152/7206 0.00392418451789 ko04710 Circadian rhythm 4/121 43/7206 0.00563242847946 ko04072 Phospholipase D signaling pathway 9/121 197/7206 0.00573719379069 ko00515 Mannose type O-glycan biosynthesis 3/121 25/7206 0.00811223005973 ko04921 Oxytocin signaling pathway 9/121 209/7206 0.00835369001285 ko04070 Phosphatidylinositol signaling system 6/121 112/7206 0.0111630143142 ko04930 Type II diabetes mellitus 4/121 54/7206 0.012537074831 ko05033 Nicotine addiction 4/121 56/7206 0.0141934642224 ko04722 Neurotrophin signaling pathway 7/121 160/7206 0.017838089198 ko04071 Sphingolipid signaling pathway 7/121 162/7206 0.018967681876 ko04010 MAPK signaling pathway 11/121 321/7206 0.0225154521517 ko04720 Long-term potentiation 5/121 99/7206 0.0251463292754 ko04931 Insulin resistance 6/121 137/7206 0.0274228354584 ko05020 Prion diseases 3/121 40/7206 0.0290679623181 ko04080 Neuroactive ligand-receptor interaction 13/121 423/7206 0.0300692693662 ko05030 Cocaine addiction 4/121 73/7206 0.0338967622277 ko04012 ErbB signaling pathway 5/121 109/7206 0.036045136118 ko00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 2/121 19/7206 0.0396952231977 ko04923 Regulation of lipolysis in adipocytes 4/121 77/7206 0.0400705872172 ko04730 Long-term depression 4/121 78/7206 0.0417077989586 ko04013 MAPK signaling pathway - fly 5/121 115/7206 0.0437945885288