ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 36/185 79/7206 2.58771801933e-37 ko05150 Staphylococcus aureus infection 11/185 36/7206 8.15418207832e-10 ko00630 Glyoxylate and dicarboxylate metabolism 9/185 38/7206 3.4197423202e-07 ko04977 Vitamin digestion and absorption 7/185 22/7206 8.07810235325e-07 ko00983 Drug metabolism - other enzymes 8/185 42/7206 9.0665150927e-06 ko01200 Carbon metabolism 13/185 128/7206 2.21284695294e-05 ko04975 Fat digestion and absorption 7/185 35/7206 2.40041642096e-05 ko03320 PPAR signaling pathway 9/185 69/7206 5.98625904844e-05 ko00260 Glycine, serine and threonine metabolism 7/185 48/7206 0.000198275138266 ko04146 Peroxisome 9/185 89/7206 0.000432036518613 ko00980 Metabolism of xenobiotics by cytochrome P450 6/185 40/7206 0.000489979809972 ko04973 Carbohydrate digestion and absorption 6/185 42/7206 0.000641759616956 ko00830 Retinol metabolism 6/185 42/7206 0.000641759616956 ko04974 Protein digestion and absorption 9/185 96/7206 0.000755538723595 ko04950 Maturity onset diabetes of the young 5/185 29/7206 0.000760093727268 ko04976 Bile secretion 8/185 80/7206 0.000969568102591 ko04614 Renin-angiotensin system 4/185 18/7206 0.00097038047842 ko05204 Chemical carcinogenesis 6/185 48/7206 0.00132174822593 ko00120 Primary bile acid biosynthesis 4/185 20/7206 0.00147594996363 ko00380 Tryptophan metabolism 6/185 50/7206 0.00164054671866 ko05133 Pertussis 8/185 87/7206 0.00167831602883 ko00500 Starch and sucrose metabolism 5/185 35/7206 0.00183454994435 ko02010 ABC transporters 5/185 39/7206 0.00299524700277 ko05020 Prion diseases 5/185 40/7206 0.00335314231606 ko04978 Mineral absorption 5/185 40/7206 0.00335314231606 ko04010 MAPK signaling pathway 1/185 321/7206 0.00336047199448 ko00340 Histidine metabolism 4/185 25/7206 0.00348648298814 ko00040 Pentose and glucuronate interconversions 4/185 26/7206 0.0040389082162 ko00770 Pantothenate and CoA biosynthesis 3/185 14/7206 0.00491804231035 ko04216 Ferroptosis 5/185 44/7206 0.00509587455142 ko05322 Systemic lupus erythematosus 10/185 151/7206 0.00534986861657 ko00232 Caffeine metabolism 2/185 5/7206 0.00622951216203 ko05200 Pathways in cancer 4/185 492/7206 0.00717135128361 ko05166 HTLV-I infection 1/185 292/7206 0.00718951979057 ko04931 Insulin resistance 9/185 137/7206 0.00851340486527 ko00720 Carbon fixation pathways in prokaryotes 3/185 17/7206 0.00868237385891 ko00680 Methane metabolism 4/185 34/7206 0.010685431742 ko00480 Glutathione metabolism 5/185 55/7206 0.0130236783869 ko00982 Drug metabolism - cytochrome P450 4/185 37/7206 0.0143398156735 ko00250 Alanine, aspartate and glutamate metabolism 4/185 38/7206 0.0157132311157 ko04922 Glucagon signaling pathway 8/185 128/7206 0.0169299627913 ko00053 Ascorbate and aldarate metabolism 3/185 22/7206 0.0179030264731 ko01212 Fatty acid metabolism 5/185 60/7206 0.0184619655903 ko00140 Steroid hormone biosynthesis 4/185 41/7206 0.0203189338695 ko01230 Biosynthesis of amino acids 6/185 85/7206 0.0216471423555 ko00072 Synthesis and degradation of ketone bodies 2/185 10/7206 0.0257611029702 ko00071 Fatty acid degradation 4/185 45/7206 0.0276335343576 ko00620 Pyruvate metabolism 4/185 46/7206 0.0296774421405 ko00270 Cysteine and methionine metabolism 4/185 47/7206 0.0318086747342 ko05034 Alcoholism 1/185 238/7206 0.0330703181703 ko00010 Glycolysis / Gluconeogenesis 5/185 74/7206 0.0409913898106 ko05134 Legionellosis 5/185 74/7206 0.0409913898106 ko05146 Amoebiasis 6/185 99/7206 0.0414875239808 ko05142 Chagas disease (American trypanosomiasis) 7/185 130/7206 0.0495081603056 ko04015 Rap1 signaling pathway 2/185 278/7206 0.0498225062685