ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 21/151 191/7206 3.36928506747e-10 ko05164 Influenza A 15/151 167/7206 1.86548209882e-06 ko04621 NOD-like receptor signaling pathway 14/151 157/7206 4.56286691663e-06 ko05321 Inflammatory bowel disease (IBD) 8/151 56/7206 1.87095099715e-05 ko04380 Osteoclast differentiation 12/151 134/7206 2.16356567425e-05 ko04658 Th1 and Th2 cell differentiation 10/151 96/7206 2.92015956207e-05 ko04650 Natural killer cell mediated cytotoxicity 10/151 97/7206 3.19804121598e-05 ko05162 Measles 11/151 120/7206 3.87964335756e-05 ko05340 Primary immunodeficiency 5/151 30/7206 0.000352902776809 ko04630 Jak-STAT signaling pathway 10/151 132/7206 0.000424442882672 ko05152 Tuberculosis 12/151 187/7206 0.000527051729396 ko05150 Staphylococcus aureus infection 5/151 36/7206 0.000843806795582 ko04672 Intestinal immune network for IgA production 5/151 37/7206 0.000959373026922 ko04217 Necroptosis 11/151 178/7206 0.00122768238295 ko04610 Complement and coagulation cascades 7/151 79/7206 0.0012667697747 ko05168 Herpes simplex infection 11/151 182/7206 0.0014697622593 ko05323 Rheumatoid arthritis 7/151 89/7206 0.00253065569095 ko04064 NF-kappa B signaling pathway 7/151 96/7206 0.00387720037028 ko04620 Toll-like receptor signaling pathway 7/151 100/7206 0.00485861696004 ko05167 Kaposi's sarcoma-associated herpesvirus infection 10/151 191/7206 0.00667087292291 ko04611 Platelet activation 9/151 163/7206 0.00708863336705 ko00120 Primary bile acid biosynthesis 3/151 20/7206 0.00791551742972 ko04622 RIG-I-like receptor signaling pathway 5/151 62/7206 0.00937550485459 ko05166 HTLV-I infection 13/151 292/7206 0.00989835111153 ko05144 Malaria 4/151 45/7206 0.0141824413465 ko04660 T cell receptor signaling pathway 7/151 124/7206 0.0151030768928 ko05142 Chagas disease (American trypanosomiasis) 7/151 130/7206 0.0191203516989 ko05320 Autoimmune thyroid disease 3/151 29/7206 0.0221255283036 ko04933 AGE-RAGE signaling pathway in diabetic complications 7/151 135/7206 0.0229986393437 ko04659 Th17 cell differentiation 6/151 106/7206 0.0235386627996 ko04512 ECM-receptor interaction 5/151 79/7206 0.0246462311515 ko05161 Hepatitis B 8/151 173/7206 0.0286103787178 ko00760 Nicotinate and nicotinamide metabolism 3/151 34/7206 0.0335996471057 ko04080 Neuroactive ligand-receptor interaction 3/151 423/7206 0.0350189392787 ko04662 B cell receptor signaling pathway 5/151 88/7206 0.036952059918 ko04668 TNF signaling pathway 6/151 120/7206 0.0398391792067 ko04330 Notch signaling pathway 4/151 62/7206 0.0404978600121 ko05160 Hepatitis C 7/151 153/7206 0.0413965079211 ko05310 Asthma 2/151 17/7206 0.0482939303499 ko05145 Toxoplasmosis 6/151 126/7206 0.0485887611421