ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	30/367	56/7206	1.0071463633e-24
ko04080	Neuroactive ligand-receptor interaction	69/367	423/7206	5.9574215237e-19
ko04744	Phototransduction	19/367	36/7206	6.66204811721e-16
ko04727	GABAergic synapse	31/367	110/7206	1.30015810198e-15
ko04724	Glutamatergic synapse	36/367	152/7206	2.54813346101e-15
ko05032	Morphine addiction	29/367	110/7206	7.58973056654e-14
ko04723	Retrograde endocannabinoid signaling	34/367	175/7206	6.97506747366e-12
ko04728	Dopaminergic synapse	35/367	185/7206	7.49667987189e-12
ko04024	cAMP signaling pathway	44/367	279/7206	9.11957521577e-12
ko04713	Circadian entrainment	27/367	136/7206	6.75793727725e-10
ko04740	Olfactory transduction	19/367	80/7206	1.13123335006e-08
ko04721	Synaptic vesicle cycle	18/367	80/7206	6.8221836456e-08
ko04725	Cholinergic synapse	26/367	160/7206	1.09821039982e-07
ko05030	Cocaine addiction	16/367	73/7206	5.42197391236e-07
ko05031	Amphetamine addiction	17/367	91/7206	2.58865052354e-06
ko04726	Serotonergic synapse	21/367	137/7206	4.94764614894e-06
ko04742	Taste transduction	13/367	61/7206	8.86127032664e-06
ko04261	Adrenergic signaling in cardiomyocytes	25/367	205/7206	5.79370618209e-05
ko04964	Proximal tubule bicarbonate reclamation	8/367	29/7206	7.00270945649e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	13/367	74/7206	7.73076791496e-05
ko04911	Insulin secretion	17/367	117/7206	7.97319227026e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/367	59/7206	0.000158230382859
ko04976	Bile secretion	13/367	80/7206	0.000176370792636
ko04260	Cardiac muscle contraction	14/367	98/7206	0.000403642385983
ko05203	Viral carcinogenesis	3/367	277/7206	0.000655560966454
ko04970	Salivary secretion	13/367	95/7206	0.000977742996801
ko04972	Pancreatic secretion	14/367	111/7206	0.0014260396169
ko05016	Huntington's disease	2/367	215/7206	0.00224816665359
ko05205	Proteoglycans in cancer	4/367	271/7206	0.00279222828482
ko04921	Oxytocin signaling pathway	21/367	209/7206	0.00333412371863
ko03013	RNA transport	1/367	166/7206	0.00343684885259
ko05164	Influenza A	1/367	167/7206	0.00349517730992
ko04978	Mineral absorption	7/367	40/7206	0.00364254270851
ko04971	Gastric acid secretion	12/367	98/7206	0.00392246909671
ko04960	Aldosterone-regulated sodium reabsorption	7/367	41/7206	0.00420478746479
ko04973	Carbohydrate digestion and absorption	7/367	42/7206	0.00483032469224
ko04621	NOD-like receptor signaling pathway	1/367	157/7206	0.00492292952359
ko04110	Cell cycle	1/367	145/7206	0.00699415196673
ko05322	Systemic lupus erythematosus	1/367	151/7206	0.00733985229589
ko04217	Necroptosis	2/367	178/7206	0.00876292429552
ko04974	Protein digestion and absorption	11/367	96/7206	0.00926307333135
ko05169	Epstein-Barr virus infection	3/367	206/7206	0.00970865742099
ko04120	Ubiquitin mediated proteolysis	1/367	138/7206	0.0101541065009
ko04022	cGMP-PKG signaling pathway	20/367	216/7206	0.0105915629822
ko05034	Alcoholism	21/367	238/7206	0.0150131533407
ko04066	HIF-1 signaling pathway	1/367	123/7206	0.0213084751692
ko05145	Toxoplasmosis	1/367	126/7206	0.0218165495226
ko01200	Carbon metabolism	1/367	128/7206	0.022438926638
ko04514	Cell adhesion molecules (CAMs)	13/367	130/7206	0.023290334776
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/367	182/7206	0.0257932810153
ko04150	mTOR signaling pathway	3/367	184/7206	0.0259005310757
ko05152	Tuberculosis	3/367	187/7206	0.0263916531238
ko05166	HTLV-I infection	7/367	292/7206	0.0290634888819
ko00604	Glycosphingolipid biosynthesis - ganglio series	3/367	14/7206	0.0313683909957
ko05162	Measles	1/367	120/7206	0.0322672394057
ko04218	Cellular senescence	3/367	177/7206	0.0358073035652
ko04540	Gap junction	12/367	128/7206	0.0387835168188
ko04068	FoxO signaling pathway	3/367	167/7206	0.048664287012