ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	139/920	423/7206	7.303006559e-29
ko04724	Glutamatergic synapse	72/920	152/7206	4.75764088008e-26
ko05033	Nicotine addiction	40/920	56/7206	4.46403078404e-24
ko05032	Morphine addiction	55/920	110/7206	1.49399888119e-21
ko04713	Circadian entrainment	62/920	136/7206	1.84760672691e-21
ko04728	Dopaminergic synapse	73/920	185/7206	1.58078186728e-20
ko04727	GABAergic synapse	52/920	110/7206	4.80168107513e-19
ko04721	Synaptic vesicle cycle	41/920	80/7206	7.31735766224e-17
ko04024	cAMP signaling pathway	87/920	279/7206	1.5725946619e-16
ko04725	Cholinergic synapse	61/920	160/7206	1.8065735674e-16
ko04723	Retrograde endocannabinoid signaling	62/920	175/7206	5.94970798777e-15
ko04020	Calcium signaling pathway	78/920	265/7206	2.72200789198e-13
ko04911	Insulin secretion	45/920	117/7206	1.26745669617e-12
ko04261	Adrenergic signaling in cardiomyocytes	63/920	205/7206	6.17075697847e-12
ko04360	Axon guidance	67/920	233/7206	3.9679603238e-11
ko04921	Oxytocin signaling pathway	62/920	209/7206	5.36422837259e-11
ko05031	Amphetamine addiction	35/920	91/7206	4.16694708993e-10
ko04726	Serotonergic synapse	44/920	137/7206	2.11659684638e-09
ko04970	Salivary secretion	34/920	95/7206	6.67152840089e-09
ko04744	Phototransduction	19/920	36/7206	8.80651493429e-09
ko04720	Long-term potentiation	34/920	99/7206	2.22519204012e-08
ko03040	Spliceosome	1/920	145/7206	9.21698242131e-08
ko04022	cGMP-PKG signaling pathway	56/920	216/7206	1.1723047076e-07
ko04070	Phosphatidylinositol signaling system	35/920	112/7206	2.03618510686e-07
ko04742	Taste transduction	23/920	61/7206	6.48110534538e-07
ko04971	Gastric acid secretion	31/920	98/7206	7.506098227e-07
ko04010	MAPK signaling pathway	71/920	321/7206	1.94254511988e-06
ko03013	RNA transport	4/920	166/7206	3.05368271709e-06
ko04925	Aldosterone synthesis and secretion	31/920	105/7206	4.42001272442e-06
ko04745	Phototransduction - fly	16/920	38/7206	6.26236978446e-06
ko05030	Cocaine addiction	24/920	73/7206	6.2964055554e-06
ko04514	Cell adhesion molecules (CAMs)	35/920	130/7206	1.28148536351e-05
ko05322	Systemic lupus erythematosus	4/920	151/7206	1.97351424257e-05
ko05203	Viral carcinogenesis	14/920	277/7206	2.02210796674e-05
ko04924	Renin secretion	26/920	86/7206	2.19216476563e-05
ko04621	NOD-like receptor signaling pathway	5/920	157/7206	4.99560842994e-05
ko04730	Long-term depression	23/920	78/7206	9.17077523788e-05
ko04740	Olfactory transduction	23/920	80/7206	0.000123804431951
ko05014	Amyotrophic lateral sclerosis (ALS)	22/920	74/7206	0.000125411634296
ko04972	Pancreatic secretion	29/920	111/7206	0.000132838146688
ko04014	Ras signaling pathway	58/920	279/7206	0.000153331647375
ko04966	Collecting duct acid secretion	11/920	26/7206	0.000172022872431
ko04141	Protein processing in endoplasmic reticulum	8/920	184/7206	0.000183017634746
ko05164	Influenza A	7/920	167/7206	0.000238650651591
ko04060	Cytokine-cytokine receptor interaction	9/920	191/7206	0.000251480668521
ko04072	Phospholipase D signaling pathway	43/920	197/7206	0.000312190738311
ko04610	Complement and coagulation cascades	1/920	79/7206	0.000495001393143
ko05168	Herpes simplex infection	9/920	182/7206	0.000647979472448
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/920	14/7206	0.000820625152749
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/920	79/7206	0.000923025180582
ko04146	Peroxisome	2/920	89/7206	0.00107912348903
ko04260	Cardiac muscle contraction	24/920	98/7206	0.00121192641183
ko04915	Estrogen signaling pathway	30/920	131/7206	0.0012896786003
ko04750	Inflammatory mediator regulation of TRP channels	28/920	122/7206	0.00151133869324
ko04064	NF-kappa B signaling pathway	3/920	96/7206	0.00183496782957
ko00562	Inositol phosphate metabolism	22/920	89/7206	0.00194685376414
ko05110	Vibrio cholerae infection	17/920	63/7206	0.00196800965144
ko04930	Type II diabetes mellitus	15/920	54/7206	0.00300953650269
ko04612	Antigen processing and presentation	2/920	77/7206	0.00318475997605
ko05414	Dilated cardiomyopathy	25/920	112/7206	0.00408300428638
ko04120	Ubiquitin mediated proteolysis	7/920	138/7206	0.00422933757218
ko04540	Gap junction	28/920	128/7206	0.00448538506541
ko05140	Leishmaniasis	2/920	75/7206	0.0046660546256
ko04626	Plant-pathogen interaction	7/920	18/7206	0.00479466385033
ko04923	Regulation of lipolysis in adipocytes	19/920	77/7206	0.0050129633553
ko04722	Neurotrophin signaling pathway	33/920	160/7206	0.00540453479217
ko05010	Alzheimer's disease	39/920	202/7206	0.00720929931661
ko04015	Rap1 signaling pathway	51/920	278/7206	0.00756011730405
ko05169	Epstein-Barr virus infection	14/920	206/7206	0.00773918130831
ko00480	Glutathione metabolism	1/920	55/7206	0.00775390192271
ko05161	Hepatitis B	11/920	173/7206	0.00779421183259
ko04973	Carbohydrate digestion and absorption	12/920	42/7206	0.00812859800306
ko04371	Apelin signaling pathway	35/920	177/7206	0.00821084310572
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/920	59/7206	0.00897313054466
ko00590	Arachidonic acid metabolism	1/920	52/7206	0.0114677400956
ko00280	Valine, leucine and isoleucine degradation	1/920	54/7206	0.0119597352986
ko04640	Hematopoietic cell lineage	2/920	64/7206	0.0138642865567
ko04960	Aldosterone-regulated sodium reabsorption	11/920	41/7206	0.0152248930447
ko04711	Circadian rhythm - fly	5/920	13/7206	0.01786449702
ko04710	Circadian rhythm	11/920	43/7206	0.0193991639784
ko05205	Proteoglycans in cancer	22/920	271/7206	0.0198895043688
ko00240	Pyrimidine metabolism	6/920	110/7206	0.0200408856179
ko04115	p53 signaling pathway	3/920	74/7206	0.0213219534819
ko00071	Fatty acid degradation	1/920	45/7206	0.0250074128543
ko00620	Pyruvate metabolism	1/920	46/7206	0.0250209554108
ko03420	Nucleotide excision repair	1/920	46/7206	0.0250209554108
ko00512	Mucin type O-glycan biosynthesis	8/920	29/7206	0.0250991523896
ko04964	Proximal tubule bicarbonate reclamation	8/920	29/7206	0.0250991523896
ko05231	Choline metabolism in cancer	26/920	134/7206	0.025750084571
ko05214	Glioma	17/920	79/7206	0.026342298613
ko04114	Oocyte meiosis	27/920	139/7206	0.0279206674833
ko04916	Melanogenesis	27/920	142/7206	0.0302440298316
ko04214	Apoptosis - fly	3/920	72/7206	0.0307283130719
ko04922	Glucagon signaling pathway	25/920	128/7206	0.0311257382227
ko04071	Sphingolipid signaling pathway	30/920	162/7206	0.031717528409
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/920	15/7206	0.0335640699524
ko05410	Hypertrophic cardiomyopathy (HCM)	20/920	100/7206	0.0345042312157
ko03022	Basal transcription factors	1/920	44/7206	0.0377208717206
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	7/920	26/7206	0.0399156353156
ko05016	Huntington's disease	18/920	215/7206	0.0487556000796