ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	160/993	423/7206	1.12448389899e-37
ko04724	Glutamatergic synapse	78/993	152/7206	7.31135746976e-29
ko05033	Nicotine addiction	43/993	56/7206	1.36215459169e-26
ko05032	Morphine addiction	60/993	110/7206	3.00447750743e-24
ko04727	GABAergic synapse	57/993	110/7206	1.27753345282e-21
ko04728	Dopaminergic synapse	77/993	185/7206	3.26814111895e-21
ko04713	Circadian entrainment	63/993	136/7206	1.86070580608e-20
ko04725	Cholinergic synapse	64/993	160/7206	9.21359016469e-17
ko04723	Retrograde endocannabinoid signaling	67/993	175/7206	2.45857439077e-16
ko04024	cAMP signaling pathway	90/993	279/7206	5.56039634628e-16
ko04721	Synaptic vesicle cycle	40/993	80/7206	7.70744719662e-15
ko04020	Calcium signaling pathway	82/993	265/7206	2.16501217362e-13
ko04726	Serotonergic synapse	53/993	137/7206	2.20822349075e-13
ko04921	Oxytocin signaling pathway	69/993	209/7206	4.95906867472e-13
ko04911	Insulin secretion	46/993	117/7206	4.50030986462e-12
ko04742	Taste transduction	30/993	61/7206	3.21216114501e-11
ko04720	Long-term potentiation	39/993	99/7206	1.82890762843e-10
ko05031	Amphetamine addiction	37/993	91/7206	1.83427281893e-10
ko04744	Phototransduction	21/993	36/7206	4.90693694832e-10
ko04261	Adrenergic signaling in cardiomyocytes	60/993	205/7206	6.04669131862e-09
ko03010	Ribosome	1/993	129/7206	1.86506528093e-07
ko03040	Spliceosome	2/993	145/7206	2.58903204037e-07
ko04970	Salivary secretion	32/993	95/7206	5.76272847353e-07
ko04925	Aldosterone synthesis and secretion	34/993	105/7206	8.891430655e-07
ko05322	Systemic lupus erythematosus	3/993	151/7206	9.3920065381e-07
ko04070	Phosphatidylinositol signaling system	35/993	112/7206	1.3572745847e-06
ko05030	Cocaine addiction	26/993	73/7206	2.00070870926e-06
ko05203	Viral carcinogenesis	14/993	277/7206	2.86923132059e-06
ko04745	Phototransduction - fly	17/993	38/7206	3.37547407794e-06
ko04971	Gastric acid secretion	31/993	98/7206	4.37737170031e-06
ko04730	Long-term depression	26/993	78/7206	8.15516590844e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/993	74/7206	9.28694589852e-06
ko05168	Herpes simplex infection	7/993	182/7206	1.02846151123e-05
ko04010	MAPK signaling pathway	71/993	321/7206	3.02439486089e-05
ko04022	cGMP-PKG signaling pathway	52/993	216/7206	3.33877105781e-05
ko04110	Cell cycle	5/993	145/7206	4.55972458578e-05
ko04072	Phospholipase D signaling pathway	48/993	197/7206	5.46084736161e-05
ko05164	Influenza A	7/993	167/7206	5.78160182038e-05
ko04710	Circadian rhythm	16/993	43/7206	0.000102708153879
ko04740	Olfactory transduction	24/993	80/7206	0.000129618759886
ko04060	Cytokine-cytokine receptor interaction	10/993	191/7206	0.000171476999002
ko04972	Pancreatic secretion	30/993	111/7206	0.000226112033623
ko03013	RNA transport	8/993	166/7206	0.000231065324684
ko05169	Epstein-Barr virus infection	12/993	206/7206	0.00030339408737
ko04612	Antigen processing and presentation	1/993	77/7206	0.000320801680454
ko04966	Collecting duct acid secretion	11/993	26/7206	0.000342383958851
ko04014	Ras signaling pathway	60/993	279/7206	0.000356382286453
ko04514	Cell adhesion molecules (CAMs)	33/993	130/7206	0.000421651124512
ko04750	Inflammatory mediator regulation of TRP channels	31/993	122/7206	0.000494655979209
ko04621	NOD-like receptor signaling pathway	8/993	157/7206	0.00060697493592
ko05162	Measles	5/993	120/7206	0.000755537717357
ko04141	Protein processing in endoplasmic reticulum	11/993	184/7206	0.00104288486397
ko04915	Estrogen signaling pathway	32/993	131/7206	0.00117826851634
ko04360	Axon guidance	50/993	233/7206	0.00131580668973
ko03008	Ribosome biogenesis in eukaryotes	2/993	79/7206	0.0014543205605
ko04626	Plant-pathogen interaction	8/993	18/7206	0.00153419000294
ko04260	Cardiac muscle contraction	25/993	98/7206	0.00168787813104
ko05140	Leishmaniasis	2/993	75/7206	0.00208060382297
ko05161	Hepatitis B	11/993	173/7206	0.00246327037784
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/993	79/7206	0.00254995567268
ko04371	Apelin signaling pathway	39/993	177/7206	0.0026330883478
ko04922	Glucagon signaling pathway	30/993	128/7206	0.00269121739973
ko04120	Ubiquitin mediated proteolysis	8/993	138/7206	0.00387575344043
ko04924	Renin secretion	22/993	86/7206	0.00390474093443
ko04964	Proximal tubule bicarbonate reclamation	10/993	29/7206	0.00394177276333
ko04064	NF-kappa B signaling pathway	4/993	96/7206	0.0040286226527
ko00562	Inositol phosphate metabolism	22/993	89/7206	0.00488963293886
ko05110	Vibrio cholerae infection	17/993	63/7206	0.00500634011051
ko04540	Gap junction	29/993	128/7206	0.00606672353285
ko04630	Jak-STAT signaling pathway	8/993	132/7206	0.00703198310944
ko00590	Arachidonic acid metabolism	1/993	52/7206	0.00749217154257
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/993	14/7206	0.00754494643349
ko04610	Complement and coagulation cascades	3/993	79/7206	0.00756946752087
ko04330	Notch signaling pathway	2/993	62/7206	0.00927077591716
ko05166	HTLV-I infection	26/993	292/7206	0.0118182830323
ko05414	Dilated cardiomyopathy	25/993	112/7206	0.0122924425851
ko04350	TGF-beta signaling pathway	6/993	103/7206	0.0140900043132
ko04930	Type II diabetes mellitus	14/993	54/7206	0.0157141744156
ko03420	Nucleotide excision repair	1/993	46/7206	0.0164695837153
ko04114	Oocyte meiosis	29/993	139/7206	0.0181033408152
ko05016	Huntington's disease	18/993	215/7206	0.0202926407305
ko04015	Rap1 signaling pathway	52/993	278/7206	0.0205962501227
ko03022	Basal transcription factors	1/993	44/7206	0.0250675665563
ko05410	Hypertrophic cardiomyopathy (HCM)	22/993	100/7206	0.0268582794503
ko04722	Neurotrophin signaling pathway	32/993	160/7206	0.0269122764647
ko00280	Valine, leucine and isoleucine degradation	2/993	54/7206	0.0277034684248
ko00480	Glutathione metabolism	2/993	55/7206	0.0282622873165
ko05230	Central carbon metabolism in cancer	18/993	81/7206	0.0340948173386
ko05034	Alcoholism	44/993	238/7206	0.0354341928125
ko00980	Metabolism of xenobiotics by cytochrome P450	1/993	40/7206	0.0359474562388
ko04214	Apoptosis - fly	4/993	72/7206	0.0388666903286
ko04622	RIG-I-like receptor signaling pathway	3/993	62/7206	0.040207094594
ko05231	Choline metabolism in cancer	27/993	134/7206	0.0416843971307
ko00680	Methane metabolism	9/993	34/7206	0.0428738456252
ko05205	Proteoglycans in cancer	26/993	271/7206	0.0474853857561
ko05214	Glioma	17/993	79/7206	0.0494887164678
ko00240	Pyrimidine metabolism	8/993	110/7206	0.0498003667874