ko pathway ratio_in_study ratio_in_pop p_value ko04110 Cell cycle 52/287 145/7206 5.70287818975e-37 ko03030 DNA replication 25/287 38/7206 1.22236053629e-26 ko04111 Cell cycle - yeast 35/287 90/7206 2.11311142706e-26 ko03460 Fanconi anemia pathway 27/287 51/7206 4.65608892282e-25 ko03440 Homologous recombination 21/287 41/7206 2.56019425765e-19 ko04113 Meiosis - yeast 26/287 70/7206 3.04446069856e-19 ko03410 Base excision repair 19/287 38/7206 2.51178765851e-17 ko03430 Mismatch repair 14/287 22/7206 4.44355153789e-15 ko00240 Pyrimidine metabolism 24/287 110/7206 4.72963986344e-12 ko03420 Nucleotide excision repair 14/287 46/7206 1.40354159269e-09 ko04114 Oocyte meiosis 22/287 139/7206 2.30012184057e-08 ko03040 Spliceosome 21/287 145/7206 2.33038221939e-07 ko04218 Cellular senescence 21/287 177/7206 6.4289881663e-06 ko04144 Endocytosis 1/287 342/7206 2.34130330983e-05 ko04115 p53 signaling pathway 12/287 74/7206 3.03689907945e-05 ko05166 HTLV-I infection 27/287 292/7206 3.97733724408e-05 ko04914 Progesterone-mediated oocyte maturation 14/287 104/7206 5.78795879267e-05 ko04014 Ras signaling pathway 1/287 279/7206 0.000236186144986 ko04810 Regulation of actin cytoskeleton 1/287 264/7206 0.000541721399964 ko03008 Ribosome biogenesis in eukaryotes 10/287 79/7206 0.00108368258834 ko04015 Rap1 signaling pathway 2/287 278/7206 0.00150326483266 ko04010 MAPK signaling pathway 3/287 321/7206 0.00183725771775 ko05206 MicroRNAs in cancer 16/287 177/7206 0.00246378291792 ko05222 Small cell lung cancer 10/287 89/7206 0.00269644962136 ko04120 Ubiquitin mediated proteolysis 13/287 138/7206 0.00328129174312 ko00230 Purine metabolism 16/287 194/7206 0.00480990450907 ko04072 Phospholipase D signaling pathway 1/287 197/7206 0.00493267402137 ko05152 Tuberculosis 1/287 187/7206 0.00716673473548 ko04060 Cytokine-cytokine receptor interaction 1/287 191/7206 0.00733731390348 ko04151 PI3K-Akt signaling pathway 6/287 390/7206 0.00735853069525 ko04360 Axon guidance 2/287 233/7206 0.00925762777245 ko05205 Proteoglycans in cancer 3/287 271/7206 0.0101155672654 ko04723 Retrograde endocannabinoid signaling 1/287 175/7206 0.0103783133929 ko05203 Viral carcinogenesis 20/287 277/7206 0.0108289843005 ko04722 Neurotrophin signaling pathway 1/287 160/7206 0.0220532847766 ko04062 Chemokine signaling pathway 2/287 201/7206 0.0256598983748 ko04024 cAMP signaling pathway 4/287 279/7206 0.0268417351863 ko04510 Focal adhesion 3/287 240/7206 0.0268734330635 ko03015 mRNA surveillance pathway 8/287 93/7206 0.0313896319513 ko04724 Glutamatergic synapse 1/287 152/7206 0.0323400334091 ko04270 Vascular smooth muscle contraction 1/287 154/7206 0.0330854667904 ko04530 Tight junction 3/287 228/7206 0.0365356328322 ko00270 Cysteine and methionine metabolism 5/287 47/7206 0.0379190015838 ko04933 AGE-RAGE signaling pathway in diabetic complications 1/287 135/7206 0.0448828683955 ko04726 Serotonergic synapse 1/287 137/7206 0.0450175578758 ko04022 cGMP-PKG signaling pathway 3/287 216/7206 0.0496068829549