ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 20/135 191/7206 2.87338958593e-10 ko05340 Primary immunodeficiency 9/135 30/7206 2.23031860219e-09 ko04650 Natural killer cell mediated cytotoxicity 13/135 97/7206 2.38944252529e-08 ko05330 Allograft rejection 7/135 24/7206 1.83924138112e-07 ko05152 Tuberculosis 16/135 187/7206 3.44280017643e-07 ko05145 Toxoplasmosis 13/135 126/7206 5.51397473922e-07 ko05320 Autoimmune thyroid disease 7/135 29/7206 7.67031558701e-07 ko04660 T cell receptor signaling pathway 12/135 124/7206 3.0496535335e-06 ko04672 Intestinal immune network for IgA production 7/135 37/7206 4.46511956372e-06 ko05321 Inflammatory bowel disease (IBD) 8/135 56/7206 8.21447375715e-06 ko04145 Phagosome 13/135 162/7206 9.4306596922e-06 ko05140 Leishmaniasis 9/135 75/7206 9.59472595778e-06 ko04658 Th1 and Th2 cell differentiation 10/135 96/7206 1.09410417736e-05 ko05310 Asthma 5/135 17/7206 1.10652068197e-05 ko04612 Antigen processing and presentation 9/135 77/7206 1.19400544501e-05 ko05332 Graft-versus-host disease 5/135 18/7206 1.5091465437e-05 ko04062 Chemokine signaling pathway 14/135 201/7206 2.14455085209e-05 ko04659 Th17 cell differentiation 10/135 106/7206 2.63593034119e-05 ko05323 Rheumatoid arthritis 9/135 89/7206 3.89112190778e-05 ko05150 Staphylococcus aureus infection 6/135 36/7206 4.74628447145e-05 ko05416 Viral myocarditis 7/135 55/7206 6.64717962778e-05 ko05162 Measles 10/135 120/7206 7.6909386653e-05 ko04514 Cell adhesion molecules (CAMs) 10/135 130/7206 0.000150629775879 ko05144 Malaria 6/135 45/7206 0.000172852703447 ko04380 Osteoclast differentiation 10/135 134/7206 0.0001935063283 ko05164 Influenza A 11/135 167/7206 0.000278252095422 ko04940 Type I diabetes mellitus 5/135 32/7206 0.000287274743216 ko04064 NF-kappa B signaling pathway 8/135 96/7206 0.00040915928118 ko04664 Fc epsilon RI signaling pathway 7/135 77/7206 0.000559646649076 ko05168 Herpes simplex infection 11/135 182/7206 0.000580885267599 ko04640 Hematopoietic cell lineage 6/135 64/7206 0.00118965872278 ko04620 Toll-like receptor signaling pathway 7/135 100/7206 0.00260992317797 ko03050 Proteasome 5/135 54/7206 0.00324635984955 ko04611 Platelet activation 9/135 163/7206 0.00341042522622 ko05133 Pertussis 6/135 87/7206 0.00564716686199 ko04666 Fc gamma R-mediated phagocytosis 7/135 122/7206 0.00778377763859 ko04630 Jak-STAT signaling pathway 7/135 132/7206 0.011747835374 ko05166 HTLV-I infection 12/135 292/7206 0.0119820279306 ko04610 Complement and coagulation cascades 5/135 79/7206 0.0159741565944 ko05167 Kaposi's sarcoma-associated herpesvirus infection 8/135 191/7206 0.0266967586278 ko04621 NOD-like receptor signaling pathway 7/135 157/7206 0.0277249807718 ko05142 Chagas disease (American trypanosomiasis) 6/135 130/7206 0.0349136245882 ko05132 Salmonella infection 5/135 98/7206 0.0364273580153 ko00051 Fructose and mannose metabolism 3/135 42/7206 0.0434288865387 ko05161 Hepatitis B 7/135 173/7206 0.0434499383007 ko00592 alpha-Linolenic acid metabolism 2/135 19/7206 0.0483904388128 ko04217 Necroptosis 7/135 178/7206 0.0493500508113