ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	145/758	423/7206	1.05199959622e-42
ko04724	Glutamatergic synapse	73/758	152/7206	1.95636021806e-32
ko05033	Nicotine addiction	43/758	56/7206	1.47497076897e-31
ko05032	Morphine addiction	53/758	110/7206	7.51606296527e-24
ko04727	GABAergic synapse	52/758	110/7206	6.24855363226e-23
ko04723	Retrograde endocannabinoid signaling	64/758	175/7206	1.45179895551e-20
ko04725	Cholinergic synapse	60/758	160/7206	5.70235704184e-20
ko04728	Dopaminergic synapse	65/758	185/7206	8.49088328977e-20
ko04713	Circadian entrainment	54/758	136/7206	2.09680041242e-19
ko04721	Synaptic vesicle cycle	40/758	80/7206	5.16717762791e-19
ko04024	cAMP signaling pathway	80/758	279/7206	5.79016459534e-18
ko04911	Insulin secretion	45/758	117/7206	9.7740171728e-16
ko04742	Taste transduction	30/758	61/7206	2.56018911701e-14
ko04921	Oxytocin signaling pathway	57/758	209/7206	4.42906775969e-12
ko04726	Serotonergic synapse	43/758	137/7206	1.41264670973e-11
ko04020	Calcium signaling pathway	65/758	265/7206	2.66133318546e-11
ko05031	Amphetamine addiction	33/758	91/7206	4.65795014346e-11
ko04261	Adrenergic signaling in cardiomyocytes	54/758	205/7206	7.14256689716e-11
ko04720	Long-term potentiation	33/758	99/7206	6.07215321789e-10
ko05030	Cocaine addiction	26/758	73/7206	8.45757892485e-09
ko04970	Salivary secretion	29/758	95/7206	6.25698321183e-08
ko04060	Cytokine-cytokine receptor interaction	2/758	191/7206	2.43253019591e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	24/758	74/7206	2.45232180581e-07
ko04010	MAPK signaling pathway	64/758	321/7206	3.20440420173e-07
ko04971	Gastric acid secretion	28/758	98/7206	4.91000094581e-07
ko04744	Phototransduction	15/758	36/7206	1.2447113614e-06
ko05203	Viral carcinogenesis	8/758	277/7206	1.94776927723e-06
ko04925	Aldosterone synthesis and secretion	28/758	105/7206	2.25917453622e-06
ko04972	Pancreatic secretion	29/758	111/7206	2.34817796399e-06
ko03040	Spliceosome	1/758	145/7206	3.18760012787e-06
ko04514	Cell adhesion molecules (CAMs)	31/758	130/7206	8.84006600632e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/758	79/7206	1.29505168861e-05
ko05164	Influenza A	3/758	167/7206	1.79988887787e-05
ko04260	Cardiac muscle contraction	25/758	98/7206	1.82008140302e-05
ko04730	Long-term depression	21/758	78/7206	3.5496058967e-05
ko04740	Olfactory transduction	21/758	80/7206	5.34589891879e-05
ko04120	Ubiquitin mediated proteolysis	2/758	138/7206	5.85930778997e-05
ko04022	cGMP-PKG signaling pathway	42/758	216/7206	6.59017990441e-05
ko05322	Systemic lupus erythematosus	3/758	151/7206	7.97845403406e-05
ko04360	Axon guidance	44/758	233/7206	0.000116950827967
ko05168	Herpes simplex infection	5/758	182/7206	0.000118810989708
ko04072	Phospholipase D signaling pathway	37/758	197/7206	0.000368877509556
ko03013	RNA transport	5/758	166/7206	0.000466707810455
ko05414	Dilated cardiomyopathy	24/758	112/7206	0.000540066618653
ko05169	Epstein-Barr virus infection	8/758	206/7206	0.000734592471623
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/758	59/7206	0.000882688738764
ko04621	NOD-like receptor signaling pathway	5/758	157/7206	0.000910592765005
ko04540	Gap junction	26/758	128/7206	0.00110770753549
ko04745	Phototransduction - fly	11/758	38/7206	0.00135633694421
ko05162	Measles	3/758	120/7206	0.00144523903855
ko04350	TGF-beta signaling pathway	2/758	103/7206	0.0017298957069
ko04924	Renin secretion	19/758	86/7206	0.00199929959983
ko04964	Proximal tubule bicarbonate reclamation	9/758	29/7206	0.00215982237978
ko04630	Jak-STAT signaling pathway	4/758	132/7206	0.00232102881887
ko04750	Inflammatory mediator regulation of TRP channels	24/758	122/7206	0.00245447378333
ko03008	Ribosome biogenesis in eukaryotes	1/758	79/7206	0.00266417714953
ko04930	Type II diabetes mellitus	13/758	54/7206	0.00323108417062
ko04141	Protein processing in endoplasmic reticulum	8/758	184/7206	0.00331413806564
ko04915	Estrogen signaling pathway	25/758	131/7206	0.0034959683665
ko04612	Antigen processing and presentation	1/758	77/7206	0.0040931837346
ko00240	Pyrimidine metabolism	3/758	110/7206	0.00421101729272
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/758	182/7206	0.00450563801188
ko04110	Cell cycle	6/758	145/7206	0.00872735147179
ko03018	RNA degradation	2/758	84/7206	0.0108051015557
ko05205	Proteoglycans in cancer	16/758	271/7206	0.0111663514355
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/758	14/7206	0.0113217933987
ko04064	NF-kappa B signaling pathway	3/758	96/7206	0.0115761543335
ko05410	Hypertrophic cardiomyopathy (HCM)	19/758	100/7206	0.0123264343921
ko04966	Collecting duct acid secretion	7/758	26/7206	0.0152592850813
ko05161	Hepatitis B	9/758	173/7206	0.0169738157963
ko04070	Phosphatidylinositol signaling system	20/758	112/7206	0.0183621229914
ko05166	HTLV-I infection	19/758	292/7206	0.0194144429673
ko05140	Leishmaniasis	2/758	75/7206	0.0215366373874
ko04146	Peroxisome	3/758	89/7206	0.022679457979
ko04976	Bile secretion	15/758	80/7206	0.0254999434651
ko00480	Glutathione metabolism	1/758	55/7206	0.0267071563974
ko01200	Carbon metabolism	6/758	128/7206	0.02821697124
ko04214	Apoptosis - fly	2/758	72/7206	0.0310696739922
ko00564	Glycerophospholipid metabolism	4/758	99/7206	0.0310812895583
ko04142	Lysosome	8/758	151/7206	0.0315826970192
ko00310	Lysine degradation	2/758	73/7206	0.0318447860048
ko04626	Plant-pathogen interaction	5/758	18/7206	0.0340362549094
ko05110	Vibrio cholerae infection	12/758	63/7206	0.0367645016408
ko04973	Carbohydrate digestion and absorption	9/758	42/7206	0.0371445977424
ko04140	Autophagy - animal	9/758	164/7206	0.0380164748498
ko04150	mTOR signaling pathway	11/758	184/7206	0.0386301253973
ko00280	Valine, leucine and isoleucine degradation	1/758	54/7206	0.0407354086198
ko04014	Ras signaling pathway	40/758	279/7206	0.0456818465345
ko04722	Neurotrophin signaling pathway	25/758	160/7206	0.049041495163
ko04210	Apoptosis	11/758	180/7206	0.0490491413717