ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	128/742	423/7206	3.43640204571e-32
ko05033	Nicotine addiction	39/742	56/7206	2.22652877991e-26
ko04724	Glutamatergic synapse	58/742	152/7206	3.16280617931e-20
ko05032	Morphine addiction	45/742	110/7206	2.59870247757e-17
ko04728	Dopaminergic synapse	57/742	185/7206	5.6029162307e-15
ko04727	GABAergic synapse	41/742	110/7206	3.23175880205e-14
ko04024	cAMP signaling pathway	72/742	279/7206	3.99430835067e-14
ko04723	Retrograde endocannabinoid signaling	51/742	175/7206	1.79292097316e-12
ko04721	Synaptic vesicle cycle	32/742	80/7206	2.38881980608e-12
ko04713	Circadian entrainment	41/742	136/7206	8.94742744092e-11
ko04360	Axon guidance	55/742	233/7206	1.99019519361e-09
ko04911	Insulin secretion	34/742	117/7206	1.06229189182e-08
ko04725	Cholinergic synapse	41/742	160/7206	1.89221610729e-08
ko05030	Cocaine addiction	25/742	73/7206	2.64448641019e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	23/742	74/7206	7.00684981708e-07
ko05203	Viral carcinogenesis	7/742	277/7206	8.59970488114e-07
ko04020	Calcium signaling pathway	53/742	265/7206	1.47057862754e-06
ko04261	Adrenergic signaling in cardiomyocytes	44/742	205/7206	1.77997994639e-06
ko04726	Serotonergic synapse	33/742	137/7206	2.41506102871e-06
ko05031	Amphetamine addiction	25/742	91/7206	2.98631373284e-06
ko03040	Spliceosome	1/742	145/7206	5.03900681494e-06
ko04742	Taste transduction	19/742	61/7206	6.28321698801e-06
ko04720	Long-term potentiation	25/742	99/7206	1.51997099386e-05
ko04970	Salivary secretion	24/742	95/7206	2.2268379955e-05
ko04514	Cell adhesion molecules (CAMs)	30/742	130/7206	2.56664618936e-05
ko03013	RNA transport	3/742	166/7206	2.66684457558e-05
ko04921	Oxytocin signaling pathway	41/742	209/7206	4.03674155125e-05
ko04010	MAPK signaling pathway	56/742	321/7206	6.68470063097e-05
ko04060	Cytokine-cytokine receptor interaction	5/742	191/7206	8.65745231841e-05
ko00515	Mannose type O-glycan biosynthesis	10/742	25/7206	9.75523167323e-05
ko05164	Influenza A	4/742	167/7206	0.000146696696734
ko01200	Carbon metabolism	2/742	128/7206	0.000182662914773
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/742	14/7206	0.00021393767191
ko04972	Pancreatic secretion	24/742	111/7206	0.000382808276388
ko05322	Systemic lupus erythematosus	4/742	151/7206	0.000597191092683
ko04744	Phototransduction	11/742	36/7206	0.000687294248996
ko04730	Long-term depression	18/742	78/7206	0.000958540676578
ko05169	Epstein-Barr virus infection	8/742	206/7206	0.00100810119424
ko00240	Pyrimidine metabolism	2/742	110/7206	0.00123568104948
ko04146	Peroxisome	1/742	89/7206	0.00124292443542
ko04120	Ubiquitin mediated proteolysis	4/742	138/7206	0.00165994861534
ko03018	RNA degradation	1/742	84/7206	0.00181901810835
ko04964	Proximal tubule bicarbonate reclamation	9/742	29/7206	0.00185902247229
ko04022	cGMP-PKG signaling pathway	37/742	216/7206	0.00192989208551
ko05162	Measles	3/742	120/7206	0.00210196324311
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/742	59/7206	0.00215511883819
ko04391	Hippo signaling pathway - fly	19/742	90/7206	0.00232445538495
ko05205	Proteoglycans in cancer	14/742	271/7206	0.0029962968623
ko03008	Ribosome biogenesis in eukaryotes	1/742	79/7206	0.00418730273481
ko04141	Protein processing in endoplasmic reticulum	8/742	184/7206	0.00448613248465
ko05168	Herpes simplex infection	8/742	182/7206	0.00609515036745
ko04260	Cardiac muscle contraction	19/742	98/7206	0.00640098533627
ko04971	Gastric acid secretion	19/742	98/7206	0.00640098533627
ko04350	TGF-beta signaling pathway	3/742	103/7206	0.00832611345616
ko04621	NOD-like receptor signaling pathway	7/742	157/7206	0.0112461697683
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/742	182/7206	0.0130554915613
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/742	15/7206	0.0142418788664
ko04015	Rap1 signaling pathway	41/742	278/7206	0.0156528851958
ko04540	Gap junction	22/742	128/7206	0.0174976198111
ko00330	Arginine and proline metabolism	1/742	61/7206	0.0184445332919
ko04915	Estrogen signaling pathway	22/742	131/7206	0.0193841955239
ko05140	Leishmaniasis	2/742	75/7206	0.0215114539919
ko04612	Antigen processing and presentation	2/742	77/7206	0.0217999432615
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/742	79/7206	0.022883078104
ko04630	Jak-STAT signaling pathway	6/742	132/7206	0.0287184379702
ko05012	Parkinson's disease	8/742	155/7206	0.0318099939662
ko04144	Endocytosis	47/742	342/7206	0.0358452185875
ko04071	Sphingolipid signaling pathway	25/742	162/7206	0.0358453467765
ko04140	Autophagy - animal	9/742	164/7206	0.0374209868891
ko05215	Prostate cancer	5/742	111/7206	0.040249840245
ko00480	Glutathione metabolism	1/742	55/7206	0.040773169517
ko04976	Bile secretion	14/742	80/7206	0.0408902446493
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/742	8/7206	0.0410091586939
ko04142	Lysosome	8/742	151/7206	0.0414415354166
ko04072	Phospholipase D signaling pathway	29/742	197/7206	0.0431439004933
ko04218	Cellular senescence	10/742	177/7206	0.0438365467274
ko04014	Ras signaling pathway	39/742	279/7206	0.0441885303238