ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	165/985	423/7206	2.00797270755e-41
ko04724	Glutamatergic synapse	81/985	152/7206	9.99659043725e-32
ko05033	Nicotine addiction	46/985	56/7206	6.27830698507e-31
ko05032	Morphine addiction	60/985	110/7206	1.94039634417e-24
ko04713	Circadian entrainment	67/985	136/7206	8.39429699701e-24
ko04727	GABAergic synapse	59/985	110/7206	1.52941313057e-23
ko04728	Dopaminergic synapse	77/985	185/7206	1.96151929282e-21
ko04721	Synaptic vesicle cycle	45/985	80/7206	2.4898763576e-19
ko04723	Retrograde endocannabinoid signaling	71/985	175/7206	4.35027760693e-19
ko04725	Cholinergic synapse	66/985	160/7206	2.88262482132e-18
ko04744	Phototransduction	28/985	36/7206	4.54506640746e-18
ko04024	cAMP signaling pathway	91/985	279/7206	1.27651206596e-16
ko04742	Taste transduction	33/985	61/7206	7.61699379754e-14
ko04020	Calcium signaling pathway	82/985	265/7206	1.05002519999e-13
ko04921	Oxytocin signaling pathway	69/985	209/7206	3.4603229031e-13
ko04726	Serotonergic synapse	52/985	137/7206	6.54501042784e-13
ko04911	Insulin secretion	47/985	117/7206	7.67139817719e-13
ko05031	Amphetamine addiction	39/985	91/7206	6.43666709998e-12
ko04740	Olfactory transduction	33/985	80/7206	9.23238867106e-10
ko04720	Long-term potentiation	37/985	99/7206	2.43012590263e-09
ko04261	Adrenergic signaling in cardiomyocytes	60/985	205/7206	3.0399554781e-09
ko05030	Cocaine addiction	30/985	73/7206	5.9980194678e-09
ko03040	Spliceosome	1/985	145/7206	2.38188867885e-08
ko04970	Salivary secretion	34/985	95/7206	3.84863320378e-08
ko04925	Aldosterone synthesis and secretion	35/985	105/7206	1.87002348166e-07
ko04971	Gastric acid secretion	33/985	98/7206	3.20087515657e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	27/985	74/7206	6.22951057687e-07
ko05203	Viral carcinogenesis	13/985	277/7206	1.06287710534e-06
ko04745	Phototransduction - fly	17/985	38/7206	3.01299455505e-06
ko05164	Influenza A	5/985	167/7206	3.59892295277e-06
ko04060	Cytokine-cytokine receptor interaction	7/985	191/7206	5.1763930943e-06
ko05322	Systemic lupus erythematosus	4/985	151/7206	5.9963621467e-06
ko05162	Measles	2/985	120/7206	6.08383283301e-06
ko04514	Cell adhesion molecules (CAMs)	36/985	130/7206	2.39499018145e-05
ko04120	Ubiquitin mediated proteolysis	4/985	138/7206	2.62846891633e-05
ko04022	cGMP-PKG signaling pathway	52/985	216/7206	2.96688734552e-05
ko04010	MAPK signaling pathway	70/985	321/7206	4.17606830663e-05
ko04966	Collecting duct acid secretion	12/985	26/7206	6.05544130028e-05
ko05168	Herpes simplex infection	8/985	182/7206	6.52220273768e-05
ko03013	RNA transport	7/985	166/7206	8.22308196384e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/985	79/7206	9.52028267354e-05
ko05169	Epstein-Barr virus infection	11/985	206/7206	0.00012574444685
ko04110	Cell cycle	6/985	145/7206	0.000210213603257
ko04621	NOD-like receptor signaling pathway	7/985	157/7206	0.000225927568388
ko05166	HTLV-I infection	20/985	292/7206	0.00024111127169
ko04260	Cardiac muscle contraction	27/985	98/7206	0.000273045086465
ko04612	Antigen processing and presentation	1/985	77/7206	0.000312933397309
ko04730	Long-term depression	23/985	78/7206	0.000331887381908
ko04350	TGF-beta signaling pathway	3/985	103/7206	0.000410528631496
ko04141	Protein processing in endoplasmic reticulum	10/985	184/7206	0.000441848305103
ko05205	Proteoglycans in cancer	19/985	271/7206	0.000584451423618
ko05110	Vibrio cholerae infection	19/985	63/7206	0.000603655145502
ko04550	Signaling pathways regulating pluripotency of stem cells	9/985	165/7206	0.000827555571503
ko05161	Hepatitis B	10/985	173/7206	0.0010873358371
ko04972	Pancreatic secretion	28/985	111/7206	0.00112037780656
ko04750	Inflammatory mediator regulation of TRP channels	30/985	122/7206	0.00119557940359
ko04070	Phosphatidylinositol signaling system	28/985	112/7206	0.00120402927292
ko04924	Renin secretion	23/985	86/7206	0.00125010036556
ko03008	Ribosome biogenesis in eukaryotes	2/985	79/7206	0.00144081399171
ko04510	Focal adhesion	17/985	240/7206	0.00153663044516
ko05140	Leishmaniasis	2/985	75/7206	0.00208937185207
ko04976	Bile secretion	21/985	80/7206	0.00264934629716
ko05215	Prostate cancer	5/985	111/7206	0.00302264934962
ko05414	Dilated cardiomyopathy	27/985	112/7206	0.00313736843524
ko04064	NF-kappa B signaling pathway	4/985	96/7206	0.00396548980437
ko00480	Glutathione metabolism	1/985	55/7206	0.00503222742653
ko04710	Circadian rhythm	13/985	43/7206	0.00549003704803
ko04540	Gap junction	29/985	128/7206	0.00583777103904
ko04072	Phospholipase D signaling pathway	41/985	197/7206	0.00589997405896
ko04915	Estrogen signaling pathway	29/985	131/7206	0.00678064552551
ko04626	Plant-pathogen interaction	7/985	18/7206	0.00703684564983
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/985	14/7206	0.00724745885962
ko04014	Ras signaling pathway	54/985	279/7206	0.00739681458098
ko04610	Complement and coagulation cascades	3/985	79/7206	0.0074456497711
ko00590	Arachidonic acid metabolism	1/985	52/7206	0.00747958514795
ko00280	Valine, leucine and isoleucine degradation	1/985	54/7206	0.00800521027685
ko04210	Apoptosis	13/985	180/7206	0.00819204615191
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/985	182/7206	0.00829126422015
ko04360	Axon guidance	46/985	233/7206	0.00860622921046
ko04657	IL-17 signaling pathway	4/985	87/7206	0.0109361695442
ko05200	Pathways in cancer	49/985	492/7206	0.0118198410254
ko04964	Proximal tubule bicarbonate reclamation	9/985	29/7206	0.0124411760838
ko05145	Toxoplasmosis	8/985	126/7206	0.0125604519962
ko04371	Apelin signaling pathway	36/985	177/7206	0.0141664999425
ko03420	Nucleotide excision repair	1/985	46/7206	0.0164457166491
ko05144	Malaria	1/985	45/7206	0.0164573184755
ko05016	Huntington's disease	18/985	215/7206	0.0201273421003
ko04630	Jak-STAT signaling pathway	9/985	132/7206	0.020447864931
ko05217	Basal cell carcinoma	3/985	68/7206	0.020487043813
ko04668	TNF signaling pathway	8/985	120/7206	0.0220904424599
ko03022	Basal transcription factors	1/985	44/7206	0.024843902235
ko05206	MicroRNAs in cancer	14/985	177/7206	0.0259000397405
ko04146	Peroxisome	5/985	89/7206	0.028019284479
ko05416	Viral myocarditis	2/985	55/7206	0.0280537273495
ko05130	Pathogenic Escherichia coli infection	4/985	77/7206	0.0286542470584
ko05321	Inflammatory bowel disease (IBD)	2/985	56/7206	0.0288649746936
ko05120	Epithelial cell signaling in Helicobacter pylori infection	20/985	92/7206	0.0312652669507
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/985	59/7206	0.0340806554617
ko04658	Th1 and Th2 cell differentiation	6/985	96/7206	0.0348115081603
ko05212	Pancreatic cancer	5/985	83/7206	0.036964073439
ko03018	RNA degradation	5/985	84/7206	0.0369666480165
ko05220	Chronic myeloid leukemia	5/985	85/7206	0.0373279524421
ko05410	Hypertrophic cardiomyopathy (HCM)	21/985	100/7206	0.0392246314393
ko04115	p53 signaling pathway	4/985	74/7206	0.0394115661996
ko05202	Transcriptional misregulation in cancer	16/985	188/7206	0.0401562130217
ko04330	Notch signaling pathway	3/985	62/7206	0.0401696089148
ko04622	RIG-I-like receptor signaling pathway	3/985	62/7206	0.0401696089148
ko00562	Inositol phosphate metabolism	19/985	89/7206	0.042367363955
ko04923	Regulation of lipolysis in adipocytes	17/985	77/7206	0.043140403194
ko04810	Regulation of actin cytoskeleton	25/985	264/7206	0.0442878775147
ko00240	Pyrimidine metabolism	8/985	110/7206	0.0496751658687