ko pathway ratio_in_study ratio_in_pop p_value ko05033 Nicotine addiction 8/65 56/7206 2.84306209152e-08 ko04080 Neuroactive ligand-receptor interaction 14/65 423/7206 1.79510585939e-05 ko04723 Retrograde endocannabinoid signaling 9/65 175/7206 2.3737120505e-05 ko04724 Glutamatergic synapse 8/65 152/7206 5.94144030861e-05 ko04721 Synaptic vesicle cycle 6/65 80/7206 7.59683602365e-05 ko04728 Dopaminergic synapse 7/65 185/7206 0.00129898912813 ko00604 Glycosphingolipid biosynthesis - ganglio series 2/65 14/7206 0.00679892520906 ko04713 Circadian entrainment 5/65 136/7206 0.00742390760615 ko04071 Sphingolipid signaling pathway 5/65 162/7206 0.0150770156253 ko04727 GABAergic synapse 4/65 110/7206 0.0170587447898 ko05032 Morphine addiction 4/65 110/7206 0.0170587447898 ko05031 Amphetamine addiction 3/65 91/7206 0.0485600706956