ko pathway ratio_in_study ratio_in_pop p_value ko05340 Primary immunodeficiency 9/115 30/7206 5.29221262453e-10 ko04060 Cytokine-cytokine receptor interaction 17/115 191/7206 6.92439503153e-09 ko04650 Natural killer cell mediated cytotoxicity 11/115 97/7206 3.31833868649e-07 ko04380 Osteoclast differentiation 12/115 134/7206 1.25867057124e-06 ko04064 NF-kappa B signaling pathway 10/115 96/7206 2.57820760382e-06 ko04660 T cell receptor signaling pathway 11/115 124/7206 3.93220814684e-06 ko04666 Fc gamma R-mediated phagocytosis 10/115 122/7206 2.22599083806e-05 ko04217 Necroptosis 12/115 178/7206 2.39783150153e-05 ko05330 Allograft rejection 5/115 24/7206 3.16456546382e-05 ko04659 Th17 cell differentiation 9/115 106/7206 4.41143763856e-05 ko05320 Autoimmune thyroid disease 5/115 29/7206 8.29602812682e-05 ko04658 Th1 and Th2 cell differentiation 8/115 96/7206 0.000135841464835 ko05152 Tuberculosis 11/115 187/7206 0.000181760279313 ko04612 Antigen processing and presentation 7/115 77/7206 0.000210012450876 ko04630 Jak-STAT signaling pathway 9/115 132/7206 0.000241181512957 ko05321 Inflammatory bowel disease (IBD) 6/115 56/7206 0.000245673364587 ko05164 Influenza A 10/115 167/7206 0.000312955524895 ko04622 RIG-I-like receptor signaling pathway 6/115 62/7206 0.00043039950482 ko05133 Pertussis 7/115 87/7206 0.000447630328213 ko04662 B cell receptor signaling pathway 7/115 88/7206 0.000479988474874 ko05162 Measles 8/115 120/7206 0.000626876365191 ko04621 NOD-like receptor signaling pathway 9/115 157/7206 0.000862438008855 ko05145 Toxoplasmosis 8/115 126/7206 0.000865662407778 ko05140 Leishmaniasis 6/115 75/7206 0.00119187869657 ko04062 Chemokine signaling pathway 10/115 201/7206 0.00133044576443 ko04664 Fc epsilon RI signaling pathway 6/115 77/7206 0.00136766587389 ko05310 Asthma 3/115 17/7206 0.0022871045298 ko05150 Staphylococcus aureus infection 4/115 36/7206 0.00244540586746 ko05332 Graft-versus-host disease 3/115 18/7206 0.00271282940489 ko04144 Endocytosis 13/115 342/7206 0.00300631453352 ko04145 Phagosome 8/115 162/7206 0.00423595386124 ko04620 Toll-like receptor signaling pathway 6/115 100/7206 0.00511588814271 ko05144 Malaria 4/115 45/7206 0.00554168066966 ko05161 Hepatitis B 8/115 173/7206 0.00627226370159 ko04670 Leukocyte transendothelial migration 7/115 151/7206 0.0102633297051 ko05416 Viral myocarditis 4/115 55/7206 0.0112332809765 ko04940 Type I diabetes mellitus 3/115 32/7206 0.0140273385355 ko04611 Platelet activation 7/115 163/7206 0.0151674561981 ko05169 Epstein-Barr virus infection 8/115 206/7206 0.0169070484995 ko05142 Chagas disease (American trypanosomiasis) 6/115 130/7206 0.0174459683044 ko04672 Intestinal immune network for IgA production 3/115 37/7206 0.0207495650677 ko04210 Apoptosis 7/115 180/7206 0.0247004348771 ko05168 Herpes simplex infection 7/115 182/7206 0.0260428154999 ko05167 Kaposi's sarcoma-associated herpesvirus infection 7/115 191/7206 0.0327036571918 ko04142 Lysosome 6/115 151/7206 0.0333716501709 ko05130 Pathogenic Escherichia coli infection 4/115 77/7206 0.0341892503059 ko04610 Complement and coagulation cascades 4/115 79/7206 0.0370608425582 ko04072 Phospholipase D signaling pathway 7/115 197/7206 0.0377292443506 ko05131 Shigellosis 4/115 82/7206 0.0416219668746