ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 37/344 79/7206 1.48796206247e-28 ko04976 Bile secretion 23/344 80/7206 1.12701410946e-12 ko04974 Protein digestion and absorption 22/344 96/7206 4.64250615119e-10 ko04975 Fat digestion and absorption 12/344 35/7206 3.57568053221e-08 ko04977 Vitamin digestion and absorption 9/344 22/7206 3.32440264292e-07 ko00983 Drug metabolism - other enzymes 12/344 42/7206 3.49822748112e-07 ko00380 Tryptophan metabolism 12/344 50/7206 2.71634503446e-06 ko05150 Staphylococcus aureus infection 10/344 36/7206 4.50807230846e-06 ko04614 Renin-angiotensin system 7/344 18/7206 1.07194759748e-05 ko00260 Glycine, serine and threonine metabolism 11/344 48/7206 1.15005861464e-05 ko04950 Maturity onset diabetes of the young 8/344 29/7206 4.41486886554e-05 ko02010 ABC transporters 9/344 39/7206 6.87976315811e-05 ko04978 Mineral absorption 9/344 40/7206 8.50930012363e-05 ko03320 PPAR signaling pathway 12/344 69/7206 8.68651972307e-05 ko00140 Steroid hormone biosynthesis 9/344 41/7206 0.000104509982487 ko05166 HTLV-I infection 2/344 292/7206 0.000114018368028 ko00350 Tyrosine metabolism 8/344 33/7206 0.000120761116266 ko00340 Histidine metabolism 7/344 25/7206 0.000121122323391 ko04973 Carbohydrate digestion and absorption 9/344 42/7206 0.00012750618566 ko00830 Retinol metabolism 9/344 42/7206 0.00012750618566 ko04360 Axon guidance 1/344 233/7206 0.00023394594924 ko00120 Primary bile acid biosynthesis 6/344 20/7206 0.000248324467734 ko00982 Drug metabolism - cytochrome P450 8/344 37/7206 0.000284057834323 ko05204 Chemical carcinogenesis 9/344 48/7206 0.000372275988175 ko00591 Linoleic acid metabolism 6/344 22/7206 0.0004407592463 ko04972 Pancreatic secretion 14/344 111/7206 0.00076212349192 ko00360 Phenylalanine metabolism 5/344 17/7206 0.000925743360649 ko00232 Caffeine metabolism 3/344 5/7206 0.00100372150338 ko04390 Hippo signaling pathway 1/344 188/7206 0.00156551527948 ko00250 Alanine, aspartate and glutamate metabolism 7/344 38/7206 0.00186163079154 ko05200 Pathways in cancer 10/344 492/7206 0.00196490799734 ko04310 Wnt signaling pathway 1/344 181/7206 0.00228836086472 ko00980 Metabolism of xenobiotics by cytochrome P450 7/344 40/7206 0.00253383937374 ko04010 MAPK signaling pathway 5/344 321/7206 0.00293564055019 ko00590 Arachidonic acid metabolism 8/344 52/7206 0.00296632859468 ko04146 Peroxisome 11/344 89/7206 0.00322493126616 ko04723 Retrograde endocannabinoid signaling 1/344 175/7206 0.00338197257529 ko00770 Pantothenate and CoA biosynthesis 4/344 14/7206 0.00348858433508 ko04144 Endocytosis 6/344 342/7206 0.00403419708786 ko00480 Glutathione metabolism 8/344 55/7206 0.00423916806005 ko05169 Epstein-Barr virus infection 2/344 206/7206 0.00435206020735 ko03013 RNA transport 1/344 166/7206 0.00489664822896 ko05034 Alcoholism 3/344 238/7206 0.00500404962088 ko05010 Alzheimer's disease 2/344 202/7206 0.00638656367138 ko05133 Pertussis 10/344 87/7206 0.00816452380514 ko00950 Isoquinoline alkaloid biosynthesis 3/344 10/7206 0.0100705527165 ko04964 Proximal tubule bicarbonate reclamation 5/344 29/7206 0.011098441441 ko00592 alpha-Linolenic acid metabolism 4/344 19/7206 0.0111850682057 ko00643 Styrene degradation 2/344 4/7206 0.0127878530759 ko05203 Viral carcinogenesis 5/344 277/7206 0.013836796978 ko04110 Cell cycle 1/344 145/7206 0.0156615679677 ko00100 Steroid biosynthesis 4/344 21/7206 0.0160228362999 ko05161 Hepatitis B 2/344 173/7206 0.0176375142879 ko04261 Adrenergic signaling in cardiomyocytes 3/344 205/7206 0.0188539726776 ko00053 Ascorbate and aldarate metabolism 4/344 22/7206 0.0188644704614 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/344 5/7206 0.0206439407911 ko04922 Glucagon signaling pathway 12/344 128/7206 0.0206602844608 ko00270 Cysteine and methionine metabolism 6/344 47/7206 0.0233029501447 ko00410 beta-Alanine metabolism 5/344 35/7206 0.0240468195345 ko00500 Starch and sucrose metabolism 5/344 35/7206 0.0240468195345 ko00330 Arginine and proline metabolism 7/344 61/7206 0.0252941873416 ko04062 Chemokine signaling pathway 3/344 201/7206 0.0268762783497 ko04913 Ovarian steroidogenesis 7/344 63/7206 0.0296026005762 ko00362 Benzoate degradation 2/344 6/7206 0.0299976600034 ko04666 Fc gamma R-mediated phagocytosis 1/344 122/7206 0.0308574091073 ko04660 T cell receptor signaling pathway 1/344 124/7206 0.0311143266318 ko00630 Glyoxylate and dicarboxylate metabolism 5/344 38/7206 0.0331262893727 ko00040 Pentose and glucuronate interconversions 4/344 26/7206 0.0332197901383 ko00650 Butanoate metabolism 4/344 26/7206 0.0332197901383 ko04621 NOD-like receptor signaling pathway 2/344 157/7206 0.0350226041552 ko05020 Prion diseases 5/344 40/7206 0.0402201091135 ko05162 Measles 1/344 120/7206 0.0468967877095 ko04668 TNF signaling pathway 1/344 120/7206 0.0468967877095 ko00401 Novobiocin biosynthesis 1/344 1/7206 0.0477379961143 ko05206 MicroRNAs in cancer 3/344 177/7206 0.0487616888534 ko04217 Necroptosis 3/344 178/7206 0.0488426105761