ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	46/795	56/7206	3.39790588481e-35
ko04724	Glutamatergic synapse	77/795	152/7206	8.80628238589e-35
ko04080	Neuroactive ligand-receptor interaction	136/795	423/7206	4.65690029413e-34
ko05032	Morphine addiction	56/795	110/7206	1.22663784072e-25
ko04713	Circadian entrainment	62/795	136/7206	6.45967232042e-25
ko04727	GABAergic synapse	55/795	110/7206	1.07796065256e-24
ko04728	Dopaminergic synapse	70/795	185/7206	3.44248232203e-22
ko04723	Retrograde endocannabinoid signaling	66/795	175/7206	7.02870082296e-21
ko04725	Cholinergic synapse	59/795	160/7206	3.24595652765e-18
ko04024	cAMP signaling pathway	80/795	279/7206	1.03130459146e-16
ko04721	Synaptic vesicle cycle	38/795	80/7206	1.90248385779e-16
ko04911	Insulin secretion	47/795	117/7206	1.9296421968e-16
ko04720	Long-term potentiation	38/795	99/7206	8.67888968666e-13
ko05031	Amphetamine addiction	36/795	91/7206	1.20848685358e-12
ko04921	Oxytocin signaling pathway	59/795	209/7206	2.8612250965e-12
ko04261	Adrenergic signaling in cardiomyocytes	57/795	205/7206	1.34075765025e-11
ko04742	Taste transduction	26/795	61/7206	2.40933943674e-10
ko04020	Calcium signaling pathway	64/795	265/7206	6.69428874509e-10
ko04744	Phototransduction	19/795	36/7206	7.30215180834e-10
ko05030	Cocaine addiction	28/795	73/7206	9.33348464698e-10
ko04726	Serotonergic synapse	40/795	137/7206	3.50355376053e-09
ko04970	Salivary secretion	31/795	95/7206	1.15589986148e-08
ko04925	Aldosterone synthesis and secretion	32/795	105/7206	4.28918828421e-08
ko04010	MAPK signaling pathway	68/795	321/7206	7.36471019529e-08
ko04060	Cytokine-cytokine receptor interaction	2/795	191/7206	1.08923973682e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	25/795	74/7206	1.41969514211e-07
ko04971	Gastric acid secretion	29/795	98/7206	3.7260472203e-07
ko03040	Spliceosome	1/795	145/7206	1.31804030429e-06
ko04072	Phospholipase D signaling pathway	45/795	197/7206	1.36253885738e-06
ko04972	Pancreatic secretion	30/795	111/7206	1.98188436966e-06
ko05203	Viral carcinogenesis	9/795	277/7206	3.0312076187e-06
ko04360	Axon guidance	50/795	233/7206	3.17451628754e-06
ko05168	Herpes simplex infection	4/795	182/7206	1.10325025726e-05
ko04514	Cell adhesion molecules (CAMs)	32/795	130/7206	1.18156917243e-05
ko04022	cGMP-PKG signaling pathway	45/795	216/7206	2.06289792879e-05
ko04730	Long-term depression	22/795	78/7206	2.21366576659e-05
ko04915	Estrogen signaling pathway	31/795	131/7206	2.91665329888e-05
ko04740	Olfactory transduction	22/795	80/7206	3.4124804468e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/795	79/7206	8.80865020095e-05
ko04745	Phototransduction - fly	13/795	38/7206	0.000126558257622
ko04350	TGF-beta signaling pathway	1/795	103/7206	0.000174546944627
ko03013	RNA transport	5/795	166/7206	0.000228969373642
ko05164	Influenza A	5/795	167/7206	0.000232357746429
ko04260	Cardiac muscle contraction	23/795	98/7206	0.000446929544496
ko04621	NOD-like receptor signaling pathway	5/795	157/7206	0.000452226325378
ko05414	Dilated cardiomyopathy	25/795	112/7206	0.000614202640738
ko04070	Phosphatidylinositol signaling system	25/795	112/7206	0.000614202640738
ko04120	Ubiquitin mediated proteolysis	4/795	138/7206	0.000821212130787
ko05322	Systemic lupus erythematosus	5/795	151/7206	0.000890990951056
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/795	59/7206	0.00144284894827
ko03008	Ribosome biogenesis in eukaryotes	1/795	79/7206	0.00175634452865
ko04141	Protein processing in endoplasmic reticulum	8/795	184/7206	0.00178427101701
ko04371	Apelin signaling pathway	33/795	177/7206	0.00219572898797
ko05169	Epstein-Barr virus infection	10/795	206/7206	0.00222621125203
ko04540	Gap junction	26/795	128/7206	0.00237891025174
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/795	14/7206	0.00243366985764
ko04924	Renin secretion	19/795	86/7206	0.00267055520019
ko04612	Antigen processing and presentation	1/795	77/7206	0.00269798171952
ko04976	Bile secretion	18/795	80/7206	0.00319849916919
ko04214	Apoptosis - fly	1/795	72/7206	0.00385273893773
ko05205	Proteoglycans in cancer	16/795	271/7206	0.00406499252519
ko04750	Inflammatory mediator regulation of TRP channels	24/795	122/7206	0.00494008955259
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/795	182/7206	0.00554222199739
ko05034	Alcoholism	40/795	238/7206	0.00597974130846
ko03018	RNA degradation	2/795	84/7206	0.00742380277043
ko04015	Rap1 signaling pathway	45/795	278/7206	0.00805253978593
ko04064	NF-kappa B signaling pathway	3/795	96/7206	0.00808994097591
ko04014	Ras signaling pathway	45/795	279/7206	0.00822021234579
ko04640	Hematopoietic cell lineage	1/795	64/7206	0.00832127059922
ko04912	GnRH signaling pathway	23/795	122/7206	0.00844724780446
ko00512	Mucin type O-glycan biosynthesis	8/795	29/7206	0.0110035491428
ko04964	Proximal tubule bicarbonate reclamation	8/795	29/7206	0.0110035491428
ko05162	Measles	5/795	120/7206	0.011817516753
ko04114	Oocyte meiosis	25/795	139/7206	0.0130584902508
ko04918	Thyroid hormone synthesis	17/795	86/7206	0.0144738427717
ko04930	Type II diabetes mellitus	12/795	54/7206	0.0147255236374
ko05140	Leishmaniasis	2/795	75/7206	0.0148052765874
ko04110	Cell cycle	7/795	145/7206	0.0149789155439
ko05410	Hypertrophic cardiomyopathy (HCM)	19/795	100/7206	0.0153003154009
ko04630	Jak-STAT signaling pathway	6/795	132/7206	0.0159885980549
ko05321	Inflammatory bowel disease (IBD)	1/795	56/7206	0.0179635642888
ko04966	Collecting duct acid secretion	7/795	26/7206	0.0194780109403
ko04916	Melanogenesis	25/795	142/7206	0.020242543554
ko04217	Necroptosis	10/795	178/7206	0.0204151112702
ko04140	Autophagy - animal	9/795	164/7206	0.0222311862802
ko04150	mTOR signaling pathway	11/795	184/7206	0.0233123170087
ko05161	Hepatitis B	10/795	173/7206	0.0260760462882
ko00480	Glutathione metabolism	1/795	55/7206	0.0273500880965
ko00240	Pyrimidine metabolism	5/795	110/7206	0.0300650345671
ko04068	FoxO signaling pathway	10/795	167/7206	0.0332151869097
ko05016	Huntington's disease	14/795	215/7206	0.0348191220847
ko05231	Choline metabolism in cancer	23/795	134/7206	0.0351877304004
ko04626	Plant-pathogen interaction	5/795	18/7206	0.0407587467616
ko01524	Platinum drug resistance	3/795	76/7206	0.0429804456795
ko04973	Carbohydrate digestion and absorption	9/795	42/7206	0.0438007326708
ko05145	Toxoplasmosis	7/795	126/7206	0.0446903048084
ko01200	Carbon metabolism	7/795	128/7206	0.0449720553906
ko04510	Focal adhesion	17/795	240/7206	0.0463221703151
ko04670	Leukocyte transendothelial migration	9/795	151/7206	0.047751927799