ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 18/150 191/7206 6.99569793912e-08 ko04621 NOD-like receptor signaling pathway 16/150 157/7206 1.32863221844e-07 ko04668 TNF signaling pathway 14/150 120/7206 1.56811586745e-07 ko05164 Influenza A 16/150 167/7206 3.13473697581e-07 ko04623 Cytosolic DNA-sensing pathway 7/150 41/7206 1.82811618726e-05 ko04380 Osteoclast differentiation 12/150 134/7206 2.0233736112e-05 ko04064 NF-kappa B signaling pathway 10/150 96/7206 2.75681626534e-05 ko05160 Hepatitis C 12/150 153/7206 7.54699945594e-05 ko04210 Apoptosis 13/150 180/7206 8.83863624714e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 13/150 191/7206 0.000161133155891 ko05162 Measles 10/150 120/7206 0.000185218390801 ko04660 T cell receptor signaling pathway 10/150 124/7206 0.00024255546873 ko05161 Hepatitis B 12/150 173/7206 0.000243040020958 ko04622 RIG-I-like receptor signaling pathway 7/150 62/7206 0.000277541960564 ko04630 Jak-STAT signaling pathway 10/150 132/7206 0.000402510731135 ko04620 Toll-like receptor signaling pathway 8/150 100/7206 0.0010795956822 ko05168 Herpes simplex infection 11/150 182/7206 0.0013927297734 ko04657 IL-17 signaling pathway 7/150 87/7206 0.0021396096756 ko04931 Insulin resistance 9/150 137/7206 0.00214763126232 ko04662 B cell receptor signaling pathway 7/150 88/7206 0.00228476348328 ko05323 Rheumatoid arthritis 7/150 89/7206 0.00243740879876 ko00643 Styrene degradation 2/150 4/7206 0.00251264934623 ko04062 Chemokine signaling pathway 11/150 201/7206 0.00305274056003 ko05134 Legionellosis 6/150 74/7206 0.00425752339383 ko04115 p53 signaling pathway 6/150 74/7206 0.00425752339383 ko04672 Intestinal immune network for IgA production 4/150 37/7206 0.00698586324978 ko05131 Shigellosis 6/150 82/7206 0.00702857674496 ko04917 Prolactin signaling pathway 6/150 87/7206 0.00931565104292 ko05221 Acute myeloid leukemia 5/150 63/7206 0.00974871553888 ko00051 Fructose and mannose metabolism 4/150 42/7206 0.0109294692585 ko04217 Necroptosis 9/150 178/7206 0.0117715720498 ko05120 Epithelial cell signaling in Helicobacter pylori infection 6/150 92/7206 0.0120914431344 ko04080 Neuroactive ligand-receptor interaction 2/150 423/7206 0.0124575026985 ko04932 Non-alcoholic fatty liver disease (NAFLD) 9/150 182/7206 0.0134711040047 ko04211 Longevity regulating pathway 7/150 123/7206 0.0140185954973 ko04658 Th1 and Th2 cell differentiation 6/150 96/7206 0.0146969802497 ko04650 Natural killer cell mediated cytotoxicity 6/150 97/7206 0.0154049541618 ko05132 Salmonella infection 6/150 98/7206 0.0161362848006 ko05142 Chagas disease (American trypanosomiasis) 7/150 130/7206 0.0185034584313 ko05166 HTLV-I infection 12/150 292/7206 0.0202825163827 ko04068 FoxO signaling pathway 8/150 167/7206 0.0229668554193 ko05340 Primary immunodeficiency 3/150 30/7206 0.0237996969781 ko05215 Prostate cancer 6/150 111/7206 0.0279185382761 ko05133 Pertussis 5/150 87/7206 0.0345736267558 ko04670 Leukocyte transendothelial migration 7/150 151/7206 0.0378194712737 ko05150 Staphylococcus aureus infection 3/150 36/7206 0.0382584611629 ko04020 Calcium signaling pathway 1/150 265/7206 0.0454540393316 ko05145 Toxoplasmosis 6/150 126/7206 0.0473084655242