ko pathway ratio_in_study ratio_in_pop p_value ko01200 Carbon metabolism 12/59 128/7206 3.23502618223e-10 ko00010 Glycolysis / Gluconeogenesis 9/59 74/7206 6.42570539419e-09 ko00020 Citrate cycle (TCA cycle) 6/59 35/7206 3.13686911818e-07 ko00620 Pyruvate metabolism 6/59 46/7206 1.68851339833e-06 ko04260 Cardiac muscle contraction 7/59 98/7206 1.32728186802e-05 ko00030 Pentose phosphate pathway 4/59 32/7206 0.0001228494737 ko05410 Hypertrophic cardiomyopathy (HCM) 6/59 100/7206 0.000152739719283 ko00680 Methane metabolism 4/59 34/7206 0.000156511563277 ko05012 Parkinson's disease 7/59 155/7206 0.000248323821743 ko05414 Dilated cardiomyopathy 6/59 112/7206 0.000284169655624 ko04022 cGMP-PKG signaling pathway 8/59 216/7206 0.000340169198106 ko05230 Central carbon metabolism in cancer 5/59 81/7206 0.000493252409981 ko00190 Oxidative phosphorylation 6/59 127/7206 0.000558544889497 ko04922 Glucagon signaling pathway 6/59 128/7206 0.000582327822323 ko01230 Biosynthesis of amino acids 5/59 85/7206 0.000615926617392 ko05416 Viral myocarditis 4/59 55/7206 0.00101280071842 ko04020 Calcium signaling pathway 8/59 265/7206 0.00130985800686 ko00710 Carbon fixation in photosynthetic organisms 3/59 27/7206 0.00132625052634 ko05016 Huntington's disease 7/59 215/7206 0.00174241223124 ko00051 Fructose and mannose metabolism 3/59 42/7206 0.00477188613039 ko05010 Alzheimer's disease 6/59 202/7206 0.00589727163235 ko04261 Adrenergic signaling in cardiomyocytes 6/59 205/7206 0.00632930471533 ko04921 Oxytocin signaling pathway 6/59 209/7206 0.0069408261009 ko04964 Proximal tubule bicarbonate reclamation 2/59 29/7206 0.0232230948088 ko02026 Biofilm formation - Escherichia coli 1/59 3/7206 0.0243656555732 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 3/59 79/7206 0.0265738567866 ko00500 Starch and sucrose metabolism 2/59 35/7206 0.0329885558378 ko04270 Vascular smooth muscle contraction 4/59 154/7206 0.0368506926416 ko04970 Salivary secretion 3/59 95/7206 0.042461435013 ko04960 Aldosterone-regulated sodium reabsorption 2/59 41/7206 0.0440718661144 ko04971 Gastric acid secretion 3/59 98/7206 0.0458704046231