ko pathway ratio_in_study ratio_in_pop p_value ko04710 Circadian rhythm 9/229 43/7206 6.20590720839e-06 ko04630 Jak-STAT signaling pathway 15/229 132/7206 1.69961060755e-05 ko04650 Natural killer cell mediated cytotoxicity 10/229 97/7206 0.000963182196796 ko04217 Necroptosis 14/229 178/7206 0.00153564378169 ko04960 Aldosterone-regulated sodium reabsorption 6/229 41/7206 0.00170750489764 ko05321 Inflammatory bowel disease (IBD) 7/229 56/7206 0.00183793303368 ko04611 Platelet activation 13/229 163/7206 0.00198372012555 ko05340 Primary immunodeficiency 5/229 30/7206 0.00230801708808 ko05164 Influenza A 13/229 167/7206 0.00246047915353 ko04060 Cytokine-cytokine receptor interaction 14/229 191/7206 0.00296751855664 ko00120 Primary bile acid biosynthesis 4/229 20/7206 0.0032227008585 ko04610 Complement and coagulation cascades 8/229 79/7206 0.00343996409309 ko04380 Osteoclast differentiation 11/229 134/7206 0.00347252822189 ko04668 TNF signaling pathway 10/229 120/7206 0.0047142067505 ko05162 Measles 10/229 120/7206 0.0047142067505 ko00220 Arginine biosynthesis 4/229 24/7206 0.00639899395436 ko05168 Herpes simplex infection 13/229 182/7206 0.00775109009914 ko04670 Leukocyte transendothelial migration 11/229 151/7206 0.00847852542947 ko04070 Phosphatidylinositol signaling system 9/229 112/7206 0.00907950720988 ko04064 NF-kappa B signaling pathway 8/229 96/7206 0.0110500068649 ko04072 Phospholipase D signaling pathway 13/229 197/7206 0.0114133897231 ko04931 Insulin resistance 10/229 137/7206 0.0116836805901 ko00564 Glycerophospholipid metabolism 8/229 99/7206 0.0131614310404 ko00362 Benzoate degradation 2/229 6/7206 0.0138610659475 ko04066 HIF-1 signaling pathway 9/229 123/7206 0.0161334736712 ko05143 African trypanosomiasis 4/229 32/7206 0.01777355024 ko04917 Prolactin signaling pathway 7/229 87/7206 0.0202768062184 ko00592 alpha-Linolenic acid metabolism 3/229 19/7206 0.0210708106947 ko04146 Peroxisome 7/229 89/7206 0.0226797389873 ko00590 Arachidonic acid metabolism 5/229 52/7206 0.0239782392896 ko04930 Type II diabetes mellitus 5/229 54/7206 0.0277372717448 ko04672 Intestinal immune network for IgA production 4/229 37/7206 0.028879189445 ko04390 Hippo signaling pathway 1/229 188/7206 0.0320366670954 ko04621 NOD-like receptor signaling pathway 10/229 157/7206 0.0335740131625 ko04664 Fc epsilon RI signaling pathway 6/229 77/7206 0.0351448352327 ko00950 Isoquinoline alkaloid biosynthesis 2/229 10/7206 0.0382446950401 ko04620 Toll-like receptor signaling pathway 7/229 100/7206 0.0394518956957 ko00330 Arginine and proline metabolism 5/229 61/7206 0.0437380665905 ko04137 Mitophagy - animal 6/229 82/7206 0.0456329192727 ko04919 Thyroid hormone signaling pathway 9/229 143/7206 0.047517373692 ko04932 Non-alcoholic fatty liver disease (NAFLD) 11/229 182/7206 0.0486262243608