ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 28/386 79/7206 1.50591599703e-16 ko04974 Protein digestion and absorption 22/386 96/7206 4.09898565954e-09 ko04976 Bile secretion 19/386 80/7206 2.57551389208e-08 ko00983 Drug metabolism - other enzymes 13/386 42/7206 1.50734758762e-07 ko00380 Tryptophan metabolism 14/386 50/7206 2.02531902607e-07 ko00982 Drug metabolism - cytochrome P450 12/386 37/7206 2.57472075724e-07 ko00350 Tyrosine metabolism 11/386 33/7206 6.01065626498e-07 ko05204 Chemical carcinogenesis 13/386 48/7206 8.48811346001e-07 ko00140 Steroid hormone biosynthesis 12/386 41/7206 9.02734010376e-07 ko00830 Retinol metabolism 12/386 42/7206 1.20353371101e-06 ko03320 PPAR signaling pathway 15/386 69/7206 2.59290228014e-06 ko00120 Primary bile acid biosynthesis 8/386 20/7206 4.49744479544e-06 ko00980 Metabolism of xenobiotics by cytochrome P450 11/386 40/7206 5.10806055692e-06 ko00260 Glycine, serine and threonine metabolism 12/386 48/7206 5.6564964282e-06 ko00643 Styrene degradation 4/386 4/7206 8.11264870777e-06 ko00590 Arachidonic acid metabolism 12/386 52/7206 1.37861574809e-05 ko00360 Phenylalanine metabolism 7/386 17/7206 1.46029955207e-05 ko04614 Renin-angiotensin system 7/386 18/7206 2.2802471973e-05 ko02010 ABC transporters 10/386 39/7206 2.71485572562e-05 ko00040 Pentose and glucuronate interconversions 8/386 26/7206 4.19623020604e-05 ko04146 Peroxisome 15/386 89/7206 6.52327939608e-05 ko05150 Staphylococcus aureus infection 9/386 36/7206 8.5507709938e-05 ko00950 Isoquinoline alkaloid biosynthesis 5/386 10/7206 8.65962138353e-05 ko00591 Linoleic acid metabolism 7/386 22/7206 0.000101357433106 ko00071 Fatty acid degradation 10/386 45/7206 0.00010206148859 ko00340 Histidine metabolism 7/386 25/7206 0.000248399444028 ko04975 Fat digestion and absorption 8/386 35/7206 0.00041331308244 ko00053 Ascorbate and aldarate metabolism 6/386 22/7206 0.00081412139865 ko04723 Retrograde endocannabinoid signaling 1/386 175/7206 0.00105245104907 ko04978 Mineral absorption 8/386 40/7206 0.00106768099735 ko00330 Arginine and proline metabolism 10/386 61/7206 0.00134065934963 ko00232 Caffeine metabolism 3/386 5/7206 0.00140662076389 ko00860 Porphyrin and chlorophyll metabolism 7/386 34/7206 0.00183099409337 ko03013 RNA transport 1/386 166/7206 0.00237017943757 ko00592 alpha-Linolenic acid metabolism 5/386 19/7206 0.00267541514392 ko00362 Benzoate degradation 3/386 6/7206 0.00270165136493 ko04144 Endocytosis 7/386 342/7206 0.00293257654346 ko00630 Glyoxylate and dicarboxylate metabolism 7/386 38/7206 0.00357156609703 ko03040 Spliceosome 1/386 145/7206 0.0047794064117 ko04110 Cell cycle 1/386 145/7206 0.0047794064117 ko05134 Legionellosis 10/386 74/7206 0.00575607980126 ko00561 Glycerolipid metabolism 9/386 63/7206 0.00598258206647 ko04310 Wnt signaling pathway 2/386 181/7206 0.00639432944328 ko05133 Pertussis 11/386 87/7206 0.00643348590519 ko04120 Ubiquitin mediated proteolysis 1/386 138/7206 0.0069455769747 ko04080 Neuroactive ligand-receptor interaction 11/386 423/7206 0.00720310581543 ko04360 Axon guidance 4/386 233/7206 0.00734089170303 ko04972 Pancreatic secretion 13/386 111/7206 0.0082681663676 ko00480 Glutathione metabolism 8/386 55/7206 0.00839473307626 ko04725 Cholinergic synapse 2/386 160/7206 0.0122916281967 ko04390 Hippo signaling pathway 3/386 188/7206 0.0134315379956 ko05203 Viral carcinogenesis 6/386 277/7206 0.0134324906247 ko04014 Ras signaling pathway 6/386 279/7206 0.013631051439 ko01212 Fatty acid metabolism 8/386 60/7206 0.0139956935873 ko04540 Gap junction 1/386 128/7206 0.0151523951389 ko04010 MAPK signaling pathway 8/386 321/7206 0.0155997579253 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/386 4/7206 0.0159777385103 ko00965 Betalain biosynthesis 2/386 4/7206 0.0159777385103 ko05166 HTLV-I infection 7/386 292/7206 0.0167303256397 ko05034 Alcoholism 5/386 238/7206 0.0185063880657 ko05016 Huntington's disease 4/386 215/7206 0.0194717027267 ko04666 Fc gamma R-mediated phagocytosis 1/386 122/7206 0.0224308813515 ko00100 Steroid biosynthesis 4/386 21/7206 0.0234898774445 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/386 5/7206 0.0256918170083 ko04977 Vitamin digestion and absorption 4/386 22/7206 0.0275306026012 ko05200 Pathways in cancer 16/386 492/7206 0.0291832872895 ko04713 Circadian entrainment 2/386 136/7206 0.0343178458465 ko04114 Oocyte meiosis 2/386 139/7206 0.0344988329523 ko00500 Starch and sucrose metabolism 5/386 35/7206 0.0370855575566 ko04350 TGF-beta signaling pathway 1/386 103/7206 0.0443041540041