ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04260	Cardiac muscle contraction	30/429	98/7206	2.17362490995e-14
ko04261	Adrenergic signaling in cardiomyocytes	44/429	205/7206	2.99413550483e-14
ko05410	Hypertrophic cardiomyopathy (HCM)	29/429	100/7206	2.84648418936e-13
ko05414	Dilated cardiomyopathy	28/429	112/7206	3.87404524419e-11
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/429	79/7206	5.4230929141e-10
ko04022	cGMP-PKG signaling pathway	38/429	216/7206	9.55934860098e-10
ko04080	Neuroactive ligand-receptor interaction	57/429	423/7206	3.60704563096e-09
ko04921	Oxytocin signaling pathway	36/429	209/7206	4.88485287067e-09
ko05010	Alzheimer's disease	35/429	202/7206	6.88308550515e-09
ko04020	Calcium signaling pathway	41/429	265/7206	1.06012039863e-08
ko04911	Insulin secretion	24/429	117/7206	6.58163405023e-08
ko04970	Salivary secretion	21/429	95/7206	1.15346087632e-07
ko04974	Protein digestion and absorption	21/429	96/7206	1.39647235328e-07
ko00010	Glycolysis / Gluconeogenesis	17/429	74/7206	1.06073409059e-06
ko04713	Circadian entrainment	24/429	136/7206	1.23227871927e-06
ko04723	Retrograde endocannabinoid signaling	28/429	175/7206	1.26237855401e-06
ko04512	ECM-receptor interaction	17/429	79/7206	2.80095109285e-06
ko04971	Gastric acid secretion	19/429	98/7206	3.83521251897e-06
ko01200	Carbon metabolism	22/429	128/7206	5.39263457714e-06
ko05033	Nicotine addiction	13/429	56/7206	1.7652230105e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	15/429	74/7206	2.31665011508e-05
ko00020	Citrate cycle (TCA cycle)	10/429	35/7206	2.40149939676e-05
ko04724	Glutamatergic synapse	23/429	152/7206	2.88901407189e-05
ko04964	Proximal tubule bicarbonate reclamation	9/429	29/7206	2.96833710609e-05
ko04510	Focal adhesion	31/429	240/7206	3.74731609283e-05
ko04922	Glucagon signaling pathway	20/429	128/7206	6.01586404899e-05
ko04727	GABAergic synapse	18/429	110/7206	7.5650057233e-05
ko00190	Oxidative phosphorylation	19/429	127/7206	0.000165977833433
ko04720	Long-term potentiation	16/429	99/7206	0.000218473410113
ko05031	Amphetamine addiction	15/429	91/7206	0.000273858213574
ko04745	Phototransduction - fly	9/429	38/7206	0.000299077261887
ko05416	Viral myocarditis	11/429	55/7206	0.000322856560928
ko05012	Parkinson's disease	21/429	155/7206	0.000382810146489
ko04626	Plant-pathogen interaction	6/429	18/7206	0.00043170010493
ko04924	Renin secretion	14/429	86/7206	0.000496266405317
ko04725	Cholinergic synapse	21/429	160/7206	0.000537947659863
ko04024	cAMP signaling pathway	31/429	279/7206	0.000673794066301
ko00710	Carbon fixation in photosynthetic organisms	7/429	27/7206	0.000790381403901
ko04060	Cytokine-cytokine receptor interaction	2/429	191/7206	0.00100406611035
ko00620	Pyruvate metabolism	9/429	46/7206	0.00132265862766
ko04978	Mineral absorption	8/429	40/7206	0.00210227640124
ko03040	Spliceosome	1/429	145/7206	0.00220594530294
ko04960	Aldosterone-regulated sodium reabsorption	8/429	41/7206	0.00247904098123
ko04721	Synaptic vesicle cycle	12/429	80/7206	0.00254053961911
ko04973	Carbohydrate digestion and absorption	8/429	42/7206	0.00290667906431
ko05161	Hepatitis B	2/429	173/7206	0.00297200134215
ko04120	Ubiquitin mediated proteolysis	1/429	138/7206	0.00321878844529
ko04972	Pancreatic secretion	15/429	111/7206	0.00331753070291
ko00680	Methane metabolism	7/429	34/7206	0.00333616680675
ko05203	Viral carcinogenesis	6/429	277/7206	0.00401836799111
ko04151	PI3K-Akt signaling pathway	37/429	390/7206	0.00406326218885
ko04140	Autophagy - animal	2/429	164/7206	0.00422497352589
ko04550	Signaling pathways regulating pluripotency of stem cells	2/429	165/7206	0.00422511972289
ko03013	RNA transport	2/429	166/7206	0.00423982947797
ko05164	Influenza A	2/429	167/7206	0.00426922356686
ko04514	Cell adhesion molecules (CAMs)	16/429	130/7206	0.00461950412437
ko04371	Apelin signaling pathway	20/429	177/7206	0.00541641623689
ko04621	NOD-like receptor signaling pathway	2/429	157/7206	0.00602062253667
ko04730	Long-term depression	11/429	78/7206	0.00611942204943
ko00250	Alanine, aspartate and glutamate metabolism	7/429	38/7206	0.00637385999554
ko04010	MAPK signaling pathway	31/429	321/7206	0.00740573526264
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/429	59/7206	0.00761063458501
ko00030	Pentose phosphate pathway	6/429	32/7206	0.0103778196461
ko04728	Dopaminergic synapse	20/429	185/7206	0.0104563692597
ko04916	Melanogenesis	16/429	142/7206	0.0115336207104
ko04270	Vascular smooth muscle contraction	17/429	154/7206	0.014096936475
ko05166	HTLV-I infection	8/429	292/7206	0.0156592626224
ko01230	Biosynthesis of amino acids	11/429	85/7206	0.0168230924483
ko04630	Jak-STAT signaling pathway	2/429	132/7206	0.0242847559392
ko04150	mTOR signaling pathway	4/429	184/7206	0.0256573305153
ko04144	Endocytosis	11/429	342/7206	0.0256606734282
ko05016	Huntington's disease	21/429	215/7206	0.0264365497915
ko04976	Bile secretion	10/429	80/7206	0.0268280543975
ko04740	Olfactory transduction	10/429	80/7206	0.0268280543975
ko04925	Aldosterone synthesis and secretion	12/429	105/7206	0.0333544036561
ko04810	Regulation of actin cytoskeleton	24/429	264/7206	0.033623615795
ko04142	Lysosome	3/429	151/7206	0.0352154150064
ko04726	Serotonergic synapse	14/429	137/7206	0.0428770362043
ko05162	Measles	2/429	120/7206	0.048441723615
ko04110	Cell cycle	3/429	145/7206	0.048591565938
ko04360	Axon guidance	21/429	233/7206	0.0490214556199