ko pathway ratio_in_study ratio_in_pop p_value ko04724 Glutamatergic synapse 24/336 152/7206 1.15227490712e-07 ko04080 Neuroactive ligand-receptor interaction 42/336 423/7206 2.26387471314e-06 ko04713 Circadian entrainment 19/336 136/7206 1.56186512741e-05 ko04744 Phototransduction 9/336 36/7206 2.88011096212e-05 ko04070 Phosphatidylinositol signaling system 15/336 112/7206 0.000199371204077 ko04020 Calcium signaling pathway 26/336 265/7206 0.000278784516019 ko04728 Dopaminergic synapse 20/336 185/7206 0.000493956895368 ko04720 Long-term potentiation 13/336 99/7206 0.000638181243719 ko05031 Amphetamine addiction 12/336 91/7206 0.000985639785335 ko05033 Nicotine addiction 9/336 56/7206 0.00101703428495 ko04745 Phototransduction - fly 7/336 38/7206 0.0016258102198 ko04726 Serotonergic synapse 15/336 137/7206 0.00171393434274 ko05032 Morphine addiction 13/336 110/7206 0.00172443856208 ko05014 Amyotrophic lateral sclerosis (ALS) 10/336 74/7206 0.00213107705847 ko00562 Inositol phosphate metabolism 11/336 89/7206 0.00268848747922 ko04911 Insulin secretion 13/336 117/7206 0.00300374736838 ko04710 Circadian rhythm 7/336 43/7206 0.00339967277221 ko05168 Herpes simplex infection 1/336 182/7206 0.00351109536058 ko04725 Cholinergic synapse 16/336 160/7206 0.00355375435212 ko04727 GABAergic synapse 12/336 110/7206 0.00498005516224 ko04971 Gastric acid secretion 11/336 98/7206 0.00568579599784 ko05169 Epstein-Barr virus infection 2/336 206/7206 0.00634586425739 ko04925 Aldosterone synthesis and secretion 11/336 105/7206 0.00947530775567 ko04014 Ras signaling pathway 22/336 279/7206 0.0134522329795 ko03040 Spliceosome 1/336 145/7206 0.0150605282413 ko05203 Viral carcinogenesis 5/336 277/7206 0.0188646762508 ko00680 Methane metabolism 5/336 34/7206 0.0195511261437 ko04711 Circadian rhythm - fly 3/336 13/7206 0.020275888244 ko04723 Retrograde endocannabinoid signaling 15/336 175/7206 0.0264894087033 ko04921 Oxytocin signaling pathway 17/336 209/7206 0.0279646105472 ko04966 Collecting duct acid secretion 4/336 26/7206 0.0308199122043 ko04740 Olfactory transduction 8/336 80/7206 0.0321662980237 ko00140 Steroid hormone biosynthesis 5/336 41/7206 0.0404830076441 ko04668 TNF signaling pathway 1/336 120/7206 0.0454233197177 ko05146 Amoebiasis 9/336 99/7206 0.0492753038432