ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	200/1207	423/7206	7.5245655609e-52
ko04724	Glutamatergic synapse	89/1207	152/7206	4.95632087742e-32
ko05033	Nicotine addiction	46/1207	56/7206	6.17720553485e-27
ko04713	Circadian entrainment	75/1207	136/7206	7.64767053083e-25
ko05032	Morphine addiction	66/1207	110/7206	7.73806018712e-25
ko04727	GABAergic synapse	65/1207	110/7206	5.95134020359e-24
ko04721	Synaptic vesicle cycle	51/1207	80/7206	3.79370268331e-21
ko04725	Cholinergic synapse	77/1207	160/7206	1.26871319259e-20
ko04728	Dopaminergic synapse	84/1207	185/7206	2.45279726714e-20
ko04020	Calcium signaling pathway	103/1207	265/7206	1.91182961755e-18
ko04726	Serotonergic synapse	65/1207	137/7206	3.49963649637e-17
ko04024	cAMP signaling pathway	104/1207	279/7206	4.29845705962e-17
ko04723	Retrograde endocannabinoid signaling	75/1207	175/7206	1.57045769992e-16
ko04921	Oxytocin signaling pathway	81/1207	209/7206	1.0497593633e-14
ko04911	Insulin secretion	54/1207	117/7206	7.48003064787e-14
ko04742	Taste transduction	36/1207	61/7206	8.696887206e-14
ko04970	Salivary secretion	45/1207	95/7206	2.99271249312e-12
ko04744	Phototransduction	24/1207	36/7206	3.1219822421e-11
ko05031	Amphetamine addiction	42/1207	91/7206	4.61079337219e-11
ko04261	Adrenergic signaling in cardiomyocytes	71/1207	205/7206	2.53543604205e-10
ko04720	Long-term potentiation	43/1207	99/7206	3.0676502852e-10
ko03040	Spliceosome	2/1207	145/7206	1.56398282029e-09
ko03010	Ribosome	1/1207	129/7206	2.60363762462e-09
ko04022	cGMP-PKG signaling pathway	68/1207	216/7206	7.72736910563e-08
ko05203	Viral carcinogenesis	17/1207	277/7206	1.10139982969e-07
ko04925	Aldosterone synthesis and secretion	40/1207	105/7206	1.14980587839e-07
ko05168	Herpes simplex infection	8/1207	182/7206	5.06627974728e-07
ko04971	Gastric acid secretion	37/1207	98/7206	7.22860436832e-07
ko03013	RNA transport	7/1207	166/7206	8.52164362907e-07
ko04740	Olfactory transduction	32/1207	80/7206	9.67004899298e-07
ko05322	Systemic lupus erythematosus	6/1207	151/7206	1.49118133061e-06
ko04360	Axon guidance	68/1207	233/7206	1.66485856211e-06
ko05030	Cocaine addiction	29/1207	73/7206	3.7261801947e-06
ko04730	Long-term depression	30/1207	78/7206	3.97026069556e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	29/1207	74/7206	4.36753219816e-06
ko04060	Cytokine-cytokine receptor interaction	11/1207	191/7206	7.37051154356e-06
ko04070	Phosphatidylinositol signaling system	38/1207	112/7206	8.60326059164e-06
ko04621	NOD-like receptor signaling pathway	8/1207	157/7206	1.19960347365e-05
ko04924	Renin secretion	31/1207	86/7206	1.362921825e-05
ko04120	Ubiquitin mediated proteolysis	6/1207	138/7206	1.41379082636e-05
ko04110	Cell cycle	7/1207	145/7206	1.55191294415e-05
ko04972	Pancreatic secretion	37/1207	111/7206	1.5885888414e-05
ko04966	Collecting duct acid secretion	14/1207	26/7206	1.66339095215e-05
ko04010	MAPK signaling pathway	83/1207	321/7206	2.30344143372e-05
ko04514	Cell adhesion molecules (CAMs)	41/1207	130/7206	2.54189295793e-05
ko04014	Ras signaling pathway	74/1207	279/7206	2.63444017856e-05
ko04540	Gap junction	40/1207	128/7206	3.94000432878e-05
ko05164	Influenza A	10/1207	167/7206	5.35659086717e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1207	79/7206	0.00011049557844
ko04141	Protein processing in endoplasmic reticulum	13/1207	184/7206	0.000128808327565
ko04072	Phospholipase D signaling pathway	54/1207	197/7206	0.000139687106938
ko04745	Phototransduction - fly	16/1207	38/7206	0.000193637868894
ko04710	Circadian rhythm	17/1207	43/7206	0.000306350036859
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/1207	79/7206	0.000380466457338
ko04976	Bile secretion	26/1207	80/7206	0.000448316936813
ko05110	Vibrio cholerae infection	22/1207	63/7206	0.000475664937938
ko04750	Inflammatory mediator regulation of TRP channels	36/1207	122/7206	0.000513385746381
ko04260	Cardiac muscle contraction	30/1207	98/7206	0.000569941442266
ko04923	Regulation of lipolysis in adipocytes	25/1207	77/7206	0.000604430070734
ko05414	Dilated cardiomyopathy	33/1207	112/7206	0.000771529548759
ko04371	Apelin signaling pathway	47/1207	177/7206	0.0010010957157
ko04612	Antigen processing and presentation	3/1207	77/7206	0.0010254142373
ko05169	Epstein-Barr virus infection	18/1207	206/7206	0.0011966623536
ko04961	Endocrine and other factor-regulated calcium reabsorption	20/1207	59/7206	0.00123467276181
ko04964	Proximal tubule bicarbonate reclamation	12/1207	29/7206	0.00146605113699
ko05140	Leishmaniasis	3/1207	75/7206	0.00152108452084
ko05166	HTLV-I infection	30/1207	292/7206	0.00175660238305
ko04330	Notch signaling pathway	2/1207	62/7206	0.00175922935832
ko04915	Estrogen signaling pathway	36/1207	131/7206	0.00192550113505
ko05161	Hepatitis B	15/1207	173/7206	0.00268169226167
ko04610	Complement and coagulation cascades	4/1207	79/7206	0.00345391703634
ko04064	NF-kappa B signaling pathway	6/1207	96/7206	0.00352751261464
ko05410	Hypertrophic cardiomyopathy (HCM)	28/1207	100/7206	0.00428108379973
ko05162	Measles	9/1207	120/7206	0.00431419752522
ko05144	Malaria	1/1207	45/7206	0.00433068858039
ko00071	Fatty acid degradation	1/1207	45/7206	0.00433068858039
ko03420	Nucleotide excision repair	1/1207	46/7206	0.00446617269236
ko04626	Plant-pathogen interaction	8/1207	18/7206	0.00544929626818
ko04922	Glucagon signaling pathway	34/1207	128/7206	0.00557462177182
ko04270	Vascular smooth muscle contraction	39/1207	154/7206	0.0061086829662
ko00562	Inositol phosphate metabolism	25/1207	89/7206	0.00631846027904
ko04214	Apoptosis - fly	4/1207	72/7206	0.00671134011183
ko03022	Basal transcription factors	1/1207	44/7206	0.00689652264893
ko04217	Necroptosis	17/1207	178/7206	0.00794116195094
ko04930	Type II diabetes mellitus	17/1207	54/7206	0.00892316129326
ko04622	RIG-I-like receptor signaling pathway	3/1207	62/7206	0.00927721666049
ko05205	Proteoglycans in cancer	30/1207	271/7206	0.00994306454859
ko04973	Carbohydrate digestion and absorption	14/1207	42/7206	0.0106967265111
ko04657	IL-17 signaling pathway	6/1207	87/7206	0.0130330206688
ko05133	Pertussis	6/1207	87/7206	0.0130330206688
ko00240	Pyrimidine metabolism	9/1207	110/7206	0.0138555538762
ko04015	Rap1 signaling pathway	62/1207	278/7206	0.0138774735147
ko05131	Shigellosis	6/1207	82/7206	0.0171909780936
ko03018	RNA degradation	6/1207	84/7206	0.0175415022848
ko04630	Jak-STAT signaling pathway	12/1207	132/7206	0.0178960467761
ko04960	Aldosterone-regulated sodium reabsorption	13/1207	41/7206	0.0184179664216
ko05321	Inflammatory bowel disease (IBD)	3/1207	56/7206	0.0184602298461
ko00480	Glutathione metabolism	3/1207	55/7206	0.0184694629986
ko04213	Longevity regulating pathway - multiple species	23/1207	86/7206	0.0190031581816
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1207	14/7206	0.0194231095912
ko04146	Peroxisome	7/1207	89/7206	0.021674255077
ko05214	Glioma	21/1207	79/7206	0.023035008978
ko00280	Valine, leucine and isoleucine degradation	3/1207	54/7206	0.0264005521013
ko04658	Th1 and Th2 cell differentiation	8/1207	96/7206	0.0266804220079
ko04912	GnRH signaling pathway	30/1207	122/7206	0.0268222965615
ko05145	Toxoplasmosis	12/1207	126/7206	0.0294899855541
ko04350	TGF-beta signaling pathway	9/1207	103/7206	0.0322153194663
ko05217	Basal cell carcinoma	5/1207	68/7206	0.0338149625967
ko03320	PPAR signaling pathway	5/1207	69/7206	0.0339754579021
ko04932	Non-alcoholic fatty liver disease (NAFLD)	20/1207	182/7206	0.0345114933755
ko05231	Choline metabolism in cancer	32/1207	134/7206	0.0346145514559
ko04916	Melanogenesis	33/1207	142/7206	0.0409636300933
ko05016	Huntington's disease	25/1207	215/7206	0.0412062996111
ko04115	p53 signaling pathway	6/1207	74/7206	0.0423301704907
ko04210	Apoptosis	20/1207	180/7206	0.0426742568892
ko05120	Epithelial cell signaling in Helicobacter pylori infection	23/1207	92/7206	0.0475099863795