ko pathway ratio_in_study ratio_in_pop p_value ko05410 Hypertrophic cardiomyopathy (HCM) 28/311 100/7206 5.52234844362e-16 ko05414 Dilated cardiomyopathy 27/311 112/7206 1.07470104152e-13 ko04260 Cardiac muscle contraction 24/311 98/7206 1.83932657581e-12 ko04974 Protein digestion and absorption 23/311 96/7206 8.87871178008e-12 ko04512 ECM-receptor interaction 19/311 79/7206 5.66055103291e-10 ko04510 Focal adhesion 31/311 240/7206 3.19382809154e-08 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 16/311 79/7206 1.79854305675e-07 ko01200 Carbon metabolism 20/311 128/7206 4.70055777474e-07 ko04261 Adrenergic signaling in cardiomyocytes 25/311 205/7206 2.16427441762e-06 ko00010 Glycolysis / Gluconeogenesis 12/311 74/7206 6.6665443087e-05 ko04020 Calcium signaling pathway 26/311 265/7206 7.53251700109e-05 ko04964 Proximal tubule bicarbonate reclamation 7/311 29/7206 0.000178979979542 ko00020 Citrate cycle (TCA cycle) 7/311 35/7206 0.000617081054149 ko05203 Viral carcinogenesis 2/311 277/7206 0.000731009099848 ko01230 Biosynthesis of amino acids 11/311 85/7206 0.000993237071282 ko04950 Maturity onset diabetes of the young 6/311 29/7206 0.00126017987775 ko04151 PI3K-Akt signaling pathway 30/311 390/7206 0.00186459438017 ko04022 cGMP-PKG signaling pathway 19/311 216/7206 0.00310024985042 ko00220 Arginine biosynthesis 5/311 24/7206 0.00312965358173 ko05167 Kaposi's sarcoma-associated herpesvirus infection 1/311 191/7206 0.00337018773117 ko04728 Dopaminergic synapse 1/311 185/7206 0.00499969603625 ko00250 Alanine, aspartate and glutamate metabolism 6/311 38/7206 0.00528619135786 ko00630 Glyoxylate and dicarboxylate metabolism 6/311 38/7206 0.00528619135786 ko00710 Carbon fixation in photosynthetic organisms 5/311 27/7206 0.00534681890195 ko04978 Mineral absorption 6/311 40/7206 0.00683852400545 ko05161 Hepatitis B 1/311 173/7206 0.00713614562921 ko04976 Bile secretion 9/311 80/7206 0.00723669142254 ko05416 Viral myocarditis 7/311 55/7206 0.00891645803459 ko04071 Sphingolipid signaling pathway 1/311 162/7206 0.0103180556006 ko04140 Autophagy - animal 1/311 164/7206 0.0103582615167 ko04550 Signaling pathways regulating pluripotency of stem cells 1/311 165/7206 0.0104098961421 ko03013 RNA transport 1/311 166/7206 0.0104826767033 ko00030 Pentose phosphate pathway 5/311 32/7206 0.0111879117629 ko00350 Tyrosine metabolism 5/311 33/7206 0.0127319830344 ko00620 Pyruvate metabolism 6/311 46/7206 0.0134530222952 ko04921 Oxytocin signaling pathway 17/311 209/7206 0.0136673437465 ko00680 Methane metabolism 5/311 34/7206 0.0144140740889 ko04722 Neurotrophin signaling pathway 1/311 160/7206 0.0157133169198 ko04060 Cytokine-cytokine receptor interaction 2/311 191/7206 0.0177375741004 ko04072 Phospholipase D signaling pathway 2/311 197/7206 0.0185807628543 ko03040 Spliceosome 1/311 145/7206 0.0216197425821 ko04210 Apoptosis 2/311 180/7206 0.0248727975974 ko05231 Choline metabolism in cancer 1/311 134/7206 0.0310752562255 ko04114 Oocyte meiosis 1/311 139/7206 0.0317826718865 ko04660 T cell receptor signaling pathway 1/311 124/7206 0.0446845313769 ko01522 Endocrine resistance 1/311 124/7206 0.0446845313769 ko00910 Nitrogen metabolism 3/311 19/7206 0.0462133299852 ko04915 Estrogen signaling pathway 1/311 131/7206 0.0462597906992