ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	35/697	56/7206	2.65394866257e-22
ko04080	Neuroactive ligand-receptor interaction	104/697	423/7206	1.57112433996e-20
ko04721	Synaptic vesicle cycle	38/697	80/7206	2.09440942848e-18
ko04724	Glutamatergic synapse	53/697	152/7206	9.00450880723e-18
ko04728	Dopaminergic synapse	54/697	185/7206	2.6349489501e-14
ko04360	Axon guidance	58/697	233/7206	5.11231620158e-12
ko04727	GABAergic synapse	36/697	110/7206	1.59395679236e-11
ko04713	Circadian entrainment	40/697	136/7206	5.11431595643e-11
ko05032	Morphine addiction	35/697	110/7206	7.51910848612e-11
ko04723	Retrograde endocannabinoid signaling	46/697	175/7206	1.26219039526e-10
ko04725	Cholinergic synapse	41/697	160/7206	3.01520052606e-09
ko04024	cAMP signaling pathway	57/697	279/7206	3.58914478777e-08
ko04261	Adrenergic signaling in cardiomyocytes	45/697	205/7206	1.01792645427e-07
ko04911	Insulin secretion	31/697	117/7206	1.15636718428e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	23/697	74/7206	2.27080355961e-07
ko04514	Cell adhesion molecules (CAMs)	32/697	130/7206	4.53138375442e-07
ko04726	Serotonergic synapse	32/697	137/7206	2.35276241825e-06
ko05203	Viral carcinogenesis	7/697	277/7206	3.66745973087e-06
ko04060	Cytokine-cytokine receptor interaction	3/697	191/7206	9.19468988678e-06
ko03040	Spliceosome	1/697	145/7206	1.14570497722e-05
ko05031	Amphetamine addiction	23/697	91/7206	1.18006243688e-05
ko04966	Collecting duct acid secretion	11/697	26/7206	1.27209166157e-05
ko04120	Ubiquitin mediated proteolysis	1/697	138/7206	2.66645275903e-05
ko05030	Cocaine addiction	19/697	73/7206	4.34304537122e-05
ko04720	Long-term potentiation	23/697	99/7206	5.07074314996e-05
ko04970	Salivary secretion	22/697	95/7206	7.74256492031e-05
ko03013	RNA transport	3/697	166/7206	8.57222284767e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/697	14/7206	0.00014365309055
ko04742	Taste transduction	16/697	61/7206	0.000156344514395
ko05110	Vibrio cholerae infection	16/697	63/7206	0.00023498268197
ko04921	Oxytocin signaling pathway	37/697	209/7206	0.000297865703856
ko04010	MAPK signaling pathway	51/697	321/7206	0.000315303278583
ko01200	Carbon metabolism	2/697	128/7206	0.000404461153026
ko05168	Herpes simplex infection	5/697	182/7206	0.000499441108709
ko04972	Pancreatic secretion	22/697	111/7206	0.000956011575346
ko05120	Epithelial cell signaling in Helicobacter pylori infection	19/697	92/7206	0.00115502327063
ko05322	Systemic lupus erythematosus	4/697	151/7206	0.00121728617911
ko04141	Protein processing in endoplasmic reticulum	6/697	184/7206	0.0013975482712
ko04146	Peroxisome	1/697	89/7206	0.00187744353243
ko04020	Calcium signaling pathway	41/697	265/7206	0.00204844076495
ko04022	cGMP-PKG signaling pathway	35/697	216/7206	0.00215440308898
ko01230	Biosynthesis of amino acids	1/697	85/7206	0.00276424469188
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	16/697	79/7206	0.00350257100856
ko03018	RNA degradation	1/697	84/7206	0.00429427557047
ko04145	Phagosome	27/697	162/7206	0.0043991899439
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/697	182/7206	0.00479906770111
ko04964	Proximal tubule bicarbonate reclamation	8/697	29/7206	0.0050116901414
ko04612	Antigen processing and presentation	1/697	77/7206	0.00597466325604
ko04744	Phototransduction	9/697	36/7206	0.00605376896347
ko04540	Gap junction	22/697	128/7206	0.00635120412969
ko00240	Pyrimidine metabolism	3/697	110/7206	0.00854161511053
ko04621	NOD-like receptor signaling pathway	6/697	157/7206	0.00893317792991
ko05016	Huntington's disease	10/697	215/7206	0.00946362985422
ko04730	Long-term depression	15/697	78/7206	0.0102433315688
ko05164	Influenza A	7/697	167/7206	0.0114670460836
ko05162	Measles	4/697	120/7206	0.0123485105853
ko04211	Longevity regulating pathway	4/697	123/7206	0.0126546093439
ko04260	Cardiac muscle contraction	17/697	98/7206	0.0150641288687
ko04971	Gastric acid secretion	17/697	98/7206	0.0150641288687
ko04140	Autophagy - animal	7/697	164/7206	0.0153741000799
ko05205	Proteoglycans in cancer	15/697	271/7206	0.0158070319544
ko04630	Jak-STAT signaling pathway	5/697	132/7206	0.0167468186939
ko04950	Maturity onset diabetes of the young	7/697	29/7206	0.0180763274756
ko05161	Hepatitis B	8/697	173/7206	0.0188243711128
ko04064	NF-kappa B signaling pathway	3/697	96/7206	0.0231734854199
ko05146	Amoebiasis	3/697	99/7206	0.0239532342038
ko04626	Plant-pathogen interaction	5/697	18/7206	0.0246118773989
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/697	59/7206	0.0265759337103
ko00561	Glycerolipid metabolism	1/697	63/7206	0.0286698114855
ko05323	Rheumatoid arthritis	15/697	89/7206	0.028962592844
ko04391	Hippo signaling pathway - fly	15/697	90/7206	0.0306688161389
ko05169	Epstein-Barr virus infection	11/697	206/7206	0.0308688416727
ko05414	Dilated cardiomyopathy	18/697	112/7206	0.0339201492605
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/697	8/7206	0.0348328891615
ko04350	TGF-beta signaling pathway	4/697	103/7206	0.0431270374688
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	4/697	15/7206	0.0499229710531