ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	93/728	145/7206	6.98787999597e-58
ko04110	Cell cycle	64/728	145/7206	6.49347125932e-27
ko03013	RNA transport	64/728	166/7206	5.71015071646e-23
ko03030	DNA replication	29/728	38/7206	5.41324494349e-22
ko04111	Cell cycle - yeast	44/728	90/7206	5.25935838689e-21
ko04080	Neuroactive ligand-receptor interaction	1/728	423/7206	7.78344443771e-19
ko03008	Ribosome biogenesis in eukaryotes	38/728	79/7206	5.45741859248e-18
ko04144	Endocytosis	2/728	342/7206	1.04538486167e-13
ko04113	Meiosis - yeast	31/728	70/7206	1.15673879433e-13
ko00240	Pyrimidine metabolism	39/728	110/7206	4.87157328357e-13
ko03460	Fanconi anemia pathway	25/728	51/7206	1.68474873513e-12
ko03015	mRNA surveillance pathway	33/728	93/7206	3.06730115615e-11
ko03410	Base excision repair	20/728	38/7206	5.52618935665e-11
ko03430	Mismatch repair	15/728	22/7206	8.81720589616e-11
ko03440	Homologous recombination	20/728	41/7206	3.2981747561e-10
ko03420	Nucleotide excision repair	18/728	46/7206	1.80103534166e-07
ko04072	Phospholipase D signaling pathway	2/728	197/7206	2.51463288454e-07
ko03018	RNA degradation	25/728	84/7206	4.03806319988e-07
ko04921	Oxytocin signaling pathway	3/728	209/7206	9.60203899931e-07
ko04024	cAMP signaling pathway	7/728	279/7206	1.26253623515e-06
ko03020	RNA polymerase	13/728	29/7206	1.50153251263e-06
ko05217	Basal cell carcinoma	21/728	68/7206	1.75826098587e-06
ko04062	Chemokine signaling pathway	3/728	201/7206	2.06315048464e-06
ko04723	Retrograde endocannabinoid signaling	2/728	175/7206	2.70814073594e-06
ko04022	cGMP-PKG signaling pathway	4/728	216/7206	2.79687579306e-06
ko04724	Glutamatergic synapse	1/728	152/7206	3.48778023087e-06
ko00230	Purine metabolism	41/728	194/7206	4.62911949879e-06
ko04621	NOD-like receptor signaling pathway	2/728	157/7206	1.26673424719e-05
ko04371	Apelin signaling pathway	3/728	177/7206	1.28397529958e-05
ko04725	Cholinergic synapse	2/728	160/7206	1.31606928118e-05
ko04915	Estrogen signaling pathway	1/728	131/7206	2.45472550071e-05
ko04060	Cytokine-cytokine receptor interaction	4/728	191/7206	2.49071031114e-05
ko04261	Adrenergic signaling in cardiomyocytes	5/728	205/7206	3.00800486061e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/728	182/7206	5.07173688342e-05
ko04726	Serotonergic synapse	2/728	137/7206	8.63931169694e-05
ko04270	Vascular smooth muscle contraction	3/728	154/7206	0.000118784310235
ko04713	Circadian entrainment	2/728	136/7206	0.000130931824101
ko05166	HTLV-I infection	50/728	292/7206	0.000147689315339
ko04727	GABAergic synapse	1/728	110/7206	0.00017483306562
ko05032	Morphine addiction	1/728	110/7206	0.00017483306562
ko04070	Phosphatidylinositol signaling system	1/728	112/7206	0.000183632524025
ko05142	Chagas disease (American trypanosomiasis)	2/728	130/7206	0.000184389261938
ko04514	Cell adhesion molecules (CAMs)	2/728	130/7206	0.000184389261938
ko03010	Ribosome	2/728	129/7206	0.000184545565776
ko04114	Oocyte meiosis	28/728	139/7206	0.000304580606229
ko04611	Platelet activation	4/728	163/7206	0.000305592930782
ko04660	T cell receptor signaling pathway	2/728	124/7206	0.000406324420709
ko04810	Regulation of actin cytoskeleton	11/728	264/7206	0.000527631338892
ko04650	Natural killer cell mediated cytotoxicity	1/728	97/7206	0.000569420812732
ko04911	Insulin secretion	2/728	117/7206	0.000569887161454
ko05146	Amoebiasis	1/728	99/7206	0.000578174705734
ko05160	Hepatitis C	4/728	153/7206	0.0005992951148
ko04728	Dopaminergic synapse	6/728	185/7206	0.000723557840192
ko04530	Tight junction	9/728	228/7206	0.000738023320546
ko04670	Leukocyte transendothelial migration	4/728	151/7206	0.000871167044824
ko04010	MAPK signaling pathway	16/728	321/7206	0.00117683833952
ko05414	Dilated cardiomyopathy	2/728	112/7206	0.00124478089537
ko00562	Inositol phosphate metabolism	1/728	89/7206	0.00124618314025
ko04925	Aldosterone synthesis and secretion	2/728	105/7206	0.00173403016076
ko04659	Th17 cell differentiation	2/728	106/7206	0.00173687611815
ko04924	Renin secretion	1/728	86/7206	0.00183965528811
ko05133	Pertussis	1/728	87/7206	0.00186411755456
ko05152	Tuberculosis	7/728	187/7206	0.00189869680583
ko04662	B cell receptor signaling pathway	1/728	88/7206	0.00191442875588
ko05169	Epstein-Barr virus infection	35/728	206/7206	0.00205565486752
ko04912	GnRH signaling pathway	3/728	122/7206	0.00211351643259
ko04510	Focal adhesion	11/728	240/7206	0.0021870969468
ko00670	One carbon pool by folate	7/728	20/7206	0.00249032392012
ko04138	Autophagy - yeast	1/728	81/7206	0.00271411270811
ko04015	Rap1 signaling pathway	14/728	278/7206	0.00304564356004
ko04014	Ras signaling pathway	14/728	279/7206	0.0030791149668
ko04668	TNF signaling pathway	3/728	120/7206	0.00313239977262
ko04151	PI3K-Akt signaling pathway	23/728	390/7206	0.00323321474099
ko04630	Jak-STAT signaling pathway	4/728	132/7206	0.00328135913746
ko04933	AGE-RAGE signaling pathway in diabetic complications	4/728	135/7206	0.00341486077762
ko05132	Salmonella infection	2/728	98/7206	0.00361781460956
ko05410	Hypertrophic cardiomyopathy (HCM)	2/728	100/7206	0.0037559898371
ko05168	Herpes simplex infection	31/728	182/7206	0.00375898766014
ko04923	Regulation of lipolysis in adipocytes	1/728	77/7206	0.00399742061687
ko04976	Bile secretion	1/728	80/7206	0.00415006426561
ko04330	Notch signaling pathway	14/728	62/7206	0.00427296101006
ko04922	Glucagon signaling pathway	4/728	128/7206	0.0045766241011
ko04910	Insulin signaling pathway	7/728	172/7206	0.00468124749177
ko04722	Neurotrophin signaling pathway	6/728	160/7206	0.00485084863304
ko04218	Cellular senescence	30/728	177/7206	0.00496224352802
ko05030	Cocaine addiction	1/728	73/7206	0.00587895603956
ko05140	Leishmaniasis	1/728	75/7206	0.00595067661594
ko04012	ErbB signaling pathway	3/728	109/7206	0.00595540840492
ko04972	Pancreatic secretion	3/728	111/7206	0.00612026714404
ko04066	HIF-1 signaling pathway	4/728	123/7206	0.00636553957166
ko05145	Toxoplasmosis	4/728	126/7206	0.00651110407234
ko04146	Peroxisome	2/728	89/7206	0.00744053204964
ko05120	Epithelial cell signaling in Helicobacter pylori infection	2/728	92/7206	0.00776516096923
ko04380	Osteoclast differentiation	5/728	134/7206	0.00891217745893
ko05231	Choline metabolism in cancer	5/728	134/7206	0.00891217745893
ko04120	Ubiquitin mediated proteolysis	24/728	138/7206	0.0093211966061
ko04071	Sphingolipid signaling pathway	7/728	162/7206	0.0114769754279
ko04620	Toll-like receptor signaling pathway	3/728	100/7206	0.0117427580382
ko04310	Wnt signaling pathway	29/728	181/7206	0.0118142568242
ko04550	Signaling pathways regulating pluripotency of stem cells	27/728	165/7206	0.0121625391527
ko04914	Progesterone-mediated oocyte maturation	19/728	104/7206	0.0124615637413
ko05211	Renal cell carcinoma	3/728	96/7206	0.0164224133916
ko04540	Gap junction	5/728	128/7206	0.0167605788672
ko04720	Long-term potentiation	3/728	99/7206	0.0170158717909
ko00564	Glycerophospholipid metabolism	3/728	99/7206	0.0170158717909
ko04622	RIG-I-like receptor signaling pathway	1/728	62/7206	0.0185357998252
ko05110	Vibrio cholerae infection	1/728	63/7206	0.0187640990704
ko04640	Hematopoietic cell lineage	1/728	64/7206	0.0192052098631
ko03050	Proteasome	11/728	54/7206	0.0204883219805
ko04931	Insulin resistance	6/728	137/7206	0.0213276831466
ko04370	VEGF signaling pathway	2/728	77/7206	0.0216381609417
ko04750	Inflammatory mediator regulation of TRP channels	5/728	122/7206	0.02236714778
ko04666	Fc gamma R-mediated phagocytosis	5/728	122/7206	0.02236714778
ko04217	Necroptosis	9/728	178/7206	0.0225514668633
ko04152	AMPK signaling pathway	8/728	161/7206	0.0244202421128
ko04712	Circadian rhythm - plant	3/728	7/7206	0.0263368919521
ko00514	Other types of O-glycan biosynthesis	7/728	30/7206	0.0268681832442
ko04962	Vasopressin-regulated water reabsorption	1/728	58/7206	0.0270885041604
ko05031	Amphetamine addiction	3/728	91/7206	0.0330891398706
ko04360	Axon guidance	14/728	233/7206	0.0351363997426
ko04390	Hippo signaling pathway	28/728	188/7206	0.0359978040602
ko05164	Influenza A	9/728	167/7206	0.0375876748453
ko04068	FoxO signaling pathway	9/728	167/7206	0.0375876748453
ko01200	Carbon metabolism	6/728	128/7206	0.0377269038747
ko04930	Type II diabetes mellitus	1/728	54/7206	0.0395091722744
ko04115	p53 signaling pathway	13/728	74/7206	0.0487116432682