ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	93/413	423/7206	4.53539900442e-32
ko04724	Glutamatergic synapse	48/413	152/7206	8.17756373782e-24
ko05033	Nicotine addiction	28/413	56/7206	1.21257627558e-20
ko04728	Dopaminergic synapse	48/413	185/7206	9.51018598011e-20
ko04723	Retrograde endocannabinoid signaling	41/413	175/7206	2.66062052085e-15
ko04727	GABAergic synapse	32/413	110/7206	4.8833097645e-15
ko04713	Circadian entrainment	34/413	136/7206	9.40513640107e-14
ko05032	Morphine addiction	30/413	110/7206	2.39761924295e-13
ko04721	Synaptic vesicle cycle	24/413	80/7206	6.74519087092e-12
ko04726	Serotonergic synapse	31/413	137/7206	2.04499756017e-11
ko05031	Amphetamine addiction	23/413	91/7206	8.48440300991e-10
ko04911	Insulin secretion	26/413	117/7206	1.36860035029e-09
ko05030	Cocaine addiction	20/413	73/7206	2.37537518487e-09
ko04024	cAMP signaling pathway	42/413	279/7206	5.11424110464e-09
ko04725	Cholinergic synapse	30/413	160/7206	5.45348663154e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	18/413	74/7206	1.14038909533e-07
ko04261	Adrenergic signaling in cardiomyocytes	31/413	205/7206	5.22156092844e-07
ko04720	Long-term potentiation	18/413	99/7206	1.04204694213e-05
ko04970	Salivary secretion	17/413	95/7206	2.27831972941e-05
ko04921	Oxytocin signaling pathway	27/413	209/7206	5.81596469228e-05
ko04020	Calcium signaling pathway	31/413	265/7206	0.00012425777828
ko04742	Taste transduction	12/413	61/7206	0.000143366212247
ko04514	Cell adhesion molecules (CAMs)	18/413	130/7206	0.000408945001564
ko04730	Long-term depression	13/413	78/7206	0.000432073330495
ko04010	MAPK signaling pathway	34/413	321/7206	0.000482176713702
ko04972	Pancreatic secretion	16/413	111/7206	0.000539649928647
ko04550	Signaling pathways regulating pluripotency of stem cells	1/413	165/7206	0.00104105053323
ko05164	Influenza A	1/413	167/7206	0.00105912831381
ko04022	cGMP-PKG signaling pathway	24/413	216/7206	0.00156713594549
ko05203	Viral carcinogenesis	5/413	277/7206	0.002139271341
ko05322	Systemic lupus erythematosus	1/413	151/7206	0.00222560407462
ko05166	HTLV-I infection	6/413	292/7206	0.00294432154523
ko04966	Collecting duct acid secretion	6/413	26/7206	0.00294845290145
ko05168	Herpes simplex infection	2/413	182/7206	0.00305753686841
ko04150	mTOR signaling pathway	2/413	184/7206	0.00315823910166
ko03040	Spliceosome	1/413	145/7206	0.00326579364809
ko04971	Gastric acid secretion	13/413	98/7206	0.00371822792607
ko04120	Ubiquitin mediated proteolysis	1/413	138/7206	0.00475733185715
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/413	59/7206	0.00596727937033
ko05034	Alcoholism	24/413	238/7206	0.00642838335099
ko04540	Gap junction	15/413	128/7206	0.00675266503301
ko04014	Ras signaling pathway	27/413	279/7206	0.00786914721416
ko04930	Type II diabetes mellitus	8/413	54/7206	0.0110976987119
ko04260	Cardiac muscle contraction	12/413	98/7206	0.0128019062014
ko04744	Phototransduction	6/413	36/7206	0.0153852044216
ko04924	Renin secretion	11/413	86/7206	0.0156823727339
ko05010	Alzheimer's disease	20/413	202/7206	0.0195986958553
ko04360	Axon guidance	22/413	233/7206	0.020574260163
ko05215	Prostate cancer	1/413	111/7206	0.0212646279149
ko04964	Proximal tubule bicarbonate reclamation	5/413	29/7206	0.0229205334551
ko04510	Focal adhesion	6/413	240/7206	0.0234678924969
ko04978	Mineral absorption	6/413	40/7206	0.0250345511217
ko05110	Vibrio cholerae infection	8/413	63/7206	0.0264683043394
ko04072	Phospholipase D signaling pathway	19/413	197/7206	0.0275197439251
ko04350	TGF-beta signaling pathway	1/413	103/7206	0.0304579930809
ko05169	Epstein-Barr virus infection	5/413	206/7206	0.0330628836038
ko04940	Type I diabetes mellitus	5/413	32/7206	0.0338034195279
ko04630	Jak-STAT signaling pathway	2/413	132/7206	0.0348257899565
ko04621	NOD-like receptor signaling pathway	3/413	157/7206	0.0353843352718
ko05120	Epithelial cell signaling in Helicobacter pylori infection	10/413	92/7206	0.0412487032518
ko05200	Pathways in cancer	18/413	492/7206	0.0436976835432
ko05205	Proteoglycans in cancer	8/413	271/7206	0.0447882862225
ko05146	Amoebiasis	1/413	99/7206	0.0453921075557
ko05161	Hepatitis B	4/413	173/7206	0.0465676198453
ko05224	Breast cancer	4/413	174/7206	0.0466130590255
ko05206	MicroRNAs in cancer	4/413	177/7206	0.0472150177522
ko04668	TNF signaling pathway	2/413	120/7206	0.0476725244016