ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04380	Osteoclast differentiation	38/815	134/7206	4.12164868492e-08
ko04060	Cytokine-cytokine receptor interaction	48/815	191/7206	7.53043383851e-08
ko03010	Ribosome	1/815	129/7206	6.95771974069e-06
ko03040	Spliceosome	2/815	145/7206	7.70044123925e-06
ko04710	Circadian rhythm	16/815	43/7206	8.55341352651e-06
ko04137	Mitophagy - animal	23/815	82/7206	2.39909866329e-05
ko04650	Natural killer cell mediated cytotoxicity	26/815	97/7206	2.5559258847e-05
ko03013	RNA transport	4/815	166/7206	3.21421521362e-05
ko04610	Complement and coagulation cascades	22/815	79/7206	4.05623945484e-05
ko04110	Cell cycle	3/815	145/7206	5.19243415077e-05
ko05323	Rheumatoid arthritis	24/815	89/7206	5.42161860058e-05
ko04070	Phosphatidylinositol signaling system	28/815	112/7206	5.43231034065e-05
ko04630	Jak-STAT signaling pathway	31/815	132/7206	6.75951907069e-05
ko04072	Phospholipase D signaling pathway	41/815	197/7206	8.55157576543e-05
ko05150	Staphylococcus aureus infection	13/815	36/7206	8.64321728097e-05
ko04068	FoxO signaling pathway	35/815	167/7206	0.000271073427872
ko04966	Collecting duct acid secretion	10/815	26/7206	0.000315163422444
ko04022	cGMP-PKG signaling pathway	42/815	216/7206	0.000413087622257
ko04621	NOD-like receptor signaling pathway	33/815	157/7206	0.000471025394794
ko04020	Calcium signaling pathway	49/815	265/7206	0.000481216744117
ko04921	Oxytocin signaling pathway	40/815	209/7206	0.000777885511465
ko00120	Primary bile acid biosynthesis	8/815	20/7206	0.000937261578307
ko05167	Kaposi's sarcoma-associated herpesvirus infection	37/815	191/7206	0.00103558948123
ko05144	Malaria	13/815	45/7206	0.00103814881903
ko05321	Inflammatory bowel disease (IBD)	15/815	56/7206	0.00104439579755
ko04922	Glucagon signaling pathway	27/815	128/7206	0.00108273529769
ko04066	HIF-1 signaling pathway	26/815	123/7206	0.00136870294738
ko04960	Aldosterone-regulated sodium reabsorption	12/815	41/7206	0.00141759131227
ko04713	Circadian entrainment	28/815	136/7206	0.00144841303455
ko04662	B cell receptor signaling pathway	20/815	88/7206	0.00189575696984
ko04930	Type II diabetes mellitus	14/815	54/7206	0.002133369222
ko00680	Methane metabolism	10/815	34/7206	0.00335635768743
ko04371	Apelin signaling pathway	33/815	177/7206	0.00360388225418
ko04611	Platelet activation	31/815	163/7206	0.00362509996647
ko04620	Toll-like receptor signaling pathway	21/815	100/7206	0.00400038398703
ko04925	Aldosterone synthesis and secretion	22/815	105/7206	0.00444997103901
ko00010	Glycolysis / Gluconeogenesis	17/815	74/7206	0.00448563306908
ko05152	Tuberculosis	34/815	187/7206	0.00467661443944
ko05034	Alcoholism	14/815	238/7206	0.00486170601982
ko04064	NF-kappa B signaling pathway	20/815	96/7206	0.00551303553312
ko00051	Fructose and mannose metabolism	11/815	42/7206	0.00571643954559
ko05217	Basal cell carcinoma	1/815	68/7206	0.00580827922985
ko04136	Autophagy - other	9/815	31/7206	0.0058399602889
ko05224	Breast cancer	9/815	174/7206	0.00728774992065
ko03015	mRNA surveillance pathway	3/815	93/7206	0.00799660168672
ko05310	Asthma	6/815	17/7206	0.00847547157544
ko04670	Leukocyte transendothelial migration	28/815	151/7206	0.00868358402965
ko05164	Influenza A	30/815	167/7206	0.0090697266656
ko04270	Vascular smooth muscle contraction	28/815	154/7206	0.00972861006365
ko04711	Circadian rhythm - fly	5/815	13/7206	0.010812300053
ko04725	Cholinergic synapse	29/815	160/7206	0.0108181947434
ko04111	Cell cycle - yeast	3/815	90/7206	0.0112701277837
ko04668	TNF signaling pathway	23/815	120/7206	0.0123492312036
ko04970	Salivary secretion	19/815	95/7206	0.0130519076019
ko04622	RIG-I-like receptor signaling pathway	14/815	62/7206	0.0132239606912
ko04750	Inflammatory mediator regulation of TRP channels	23/815	122/7206	0.0132603295689
ko05418	Fluid shear stress and atherosclerosis	30/815	173/7206	0.0148518142411
ko04640	Hematopoietic cell lineage	14/815	64/7206	0.0149297123645
ko04971	Gastric acid secretion	19/815	98/7206	0.0156244039728
ko04923	Regulation of lipolysis in adipocytes	16/815	77/7206	0.0165592721001
ko05322	Systemic lupus erythematosus	8/815	151/7206	0.0184031118853
ko04261	Adrenergic signaling in cardiomyocytes	34/815	205/7206	0.0187965588711
ko05162	Measles	22/815	120/7206	0.019462062406
ko04120	Ubiquitin mediated proteolysis	7/815	138/7206	0.0198773239422
ko04024	cAMP signaling pathway	44/815	279/7206	0.0203863479818
ko04138	Autophagy - yeast	16/815	81/7206	0.0214507182929
ko05145	Toxoplasmosis	23/815	126/7206	0.0217847804169
ko04217	Necroptosis	30/815	178/7206	0.0224947216231
ko04145	Phagosome	28/815	162/7206	0.0228720013729
ko04919	Thyroid hormone signaling pathway	25/815	143/7206	0.0231554124997
ko04213	Longevity regulating pathway - multiple species	17/815	86/7206	0.0237467566326
ko04062	Chemokine signaling pathway	33/815	201/7206	0.0239081955288
ko04140	Autophagy - animal	28/815	164/7206	0.0241175322873
ko05133	Pertussis	17/815	87/7206	0.0246875920552
ko05140	Leishmaniasis	15/815	75/7206	0.0257939475091
ko05203	Viral carcinogenesis	20/815	277/7206	0.0259800238936
ko05110	Vibrio cholerae infection	13/815	63/7206	0.0266070347827
ko04390	Hippo signaling pathway	12/815	188/7206	0.0267026192243
ko04911	Insulin secretion	21/815	117/7206	0.0271913053676
ko00562	Inositol phosphate metabolism	17/815	89/7206	0.0272157990535
ko04666	Fc gamma R-mediated phagocytosis	22/815	122/7206	0.0289396054241
ko04727	GABAergic synapse	20/815	110/7206	0.0319449245621
ko05032	Morphine addiction	20/815	110/7206	0.0319449245621
ko04745	Phototransduction - fly	9/815	38/7206	0.0333390769621
ko04550	Signaling pathways regulating pluripotency of stem cells	10/815	165/7206	0.0334092170069
ko02010	ABC transporters	9/815	39/7206	0.0361705892994
ko01230	Biosynthesis of amino acids	16/815	85/7206	0.0370229682868
ko04964	Proximal tubule bicarbonate reclamation	7/815	29/7206	0.0389144317835
ko04924	Renin secretion	16/815	86/7206	0.039022608962
ko04933	AGE-RAGE signaling pathway in diabetic complications	23/815	135/7206	0.039374710713
ko04659	Th17 cell differentiation	19/815	106/7206	0.042557437859
ko00140	Steroid hormone biosynthesis	9/815	41/7206	0.0436415818555
ko04141	Protein processing in endoplasmic reticulum	12/815	184/7206	0.0438163045945
ko05120	Epithelial cell signaling in Helicobacter pylori infection	17/815	92/7206	0.0442073098843
ko04626	Plant-pathogen interaction	5/815	18/7206	0.0447212740318
ko00190	Oxidative phosphorylation	22/815	127/7206	0.0459623218544
ko05330	Allograft rejection	6/815	24/7206	0.0465262269117
ko05142	Chagas disease (American trypanosomiasis)	22/815	130/7206	0.0494552748669