ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 68/340 145/7206 7.8314677378e-53 ko03013 RNA transport 41/340 166/7206 2.91481296738e-19 ko03008 Ribosome biogenesis in eukaryotes 20/340 79/7206 3.56439205879e-10 ko03030 DNA replication 14/340 38/7206 7.17646605181e-10 ko00240 Pyrimidine metabolism 20/340 110/7206 1.53917640122e-07 ko03015 mRNA surveillance pathway 18/340 93/7206 2.44673574547e-07 ko03018 RNA degradation 17/340 84/7206 2.70723687817e-07 ko03410 Base excision repair 11/340 38/7206 8.38575187074e-07 ko03420 Nucleotide excision repair 11/340 46/7206 6.61514317737e-06 ko05168 Herpes simplex infection 23/340 182/7206 1.3408467394e-05 ko04110 Cell cycle 20/340 145/7206 1.34950952568e-05 ko03020 RNA polymerase 8/340 29/7206 4.05983108382e-05 ko03430 Mismatch repair 7/340 22/7206 4.51381175474e-05 ko03460 Fanconi anemia pathway 10/340 51/7206 0.000108370740817 ko05169 Epstein-Barr virus infection 22/340 206/7206 0.000304008958139 ko03440 Homologous recombination 8/340 41/7206 0.000550337655626 ko04120 Ubiquitin mediated proteolysis 16/340 138/7206 0.000740019671751 ko04060 Cytokine-cytokine receptor interaction 1/340 191/7206 0.00156766026748 ko04712 Circadian rhythm - plant 3/340 7/7206 0.00316176850608 ko04111 Cell cycle - yeast 11/340 90/7206 0.00321937596469 ko03060 Protein export 5/340 23/7206 0.00378002039882 ko03022 Basal transcription factors 7/340 44/7206 0.00414718703289 ko00230 Purine metabolism 18/340 194/7206 0.00532357941956 ko05010 Alzheimer's disease 2/340 202/7206 0.00625896391611 ko04139 Mitophagy - yeast 6/340 37/7206 0.00710043889423 ko04144 Endocytosis 7/340 342/7206 0.0126611157785 ko03050 Proteasome 7/340 54/7206 0.0128280762655 ko04022 cGMP-PKG signaling pathway 3/340 216/7206 0.0136136451824 ko04113 Meiosis - yeast 8/340 70/7206 0.0166425457585 ko04261 Adrenergic signaling in cardiomyocytes 3/340 205/7206 0.0187922873457 ko04115 p53 signaling pathway 8/340 74/7206 0.0226090846072 ko04530 Tight junction 4/340 228/7206 0.0258545679201 ko04624 Toll and Imd signaling pathway 6/340 49/7206 0.0266691735978 ko03450 Non-homologous end-joining 3/340 15/7206 0.0310478923613 ko01200 Carbon metabolism 1/340 128/7206 0.0318552854522 ko04922 Glucagon signaling pathway 1/340 128/7206 0.0318552854522 ko03010 Ribosome 1/340 129/7206 0.0322525709702 ko04514 Cell adhesion molecules (CAMs) 1/340 130/7206 0.032716588956 ko04145 Phagosome 2/340 162/7206 0.0360034874386 ko04024 cAMP signaling pathway 6/340 279/7206 0.0419997854654 ko04623 Cytosolic DNA-sensing pathway 5/340 41/7206 0.0422612182579 ko04218 Cellular senescence 14/340 177/7206 0.0483924958629 ko04724 Glutamatergic synapse 2/340 152/7206 0.0496425621949