ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	76/756	152/7206	2.23331955394e-35
ko04080	Neuroactive ligand-receptor interaction	134/756	423/7206	3.22112196585e-35
ko05033	Nicotine addiction	42/756	56/7206	3.66077691248e-30
ko05032	Morphine addiction	54/756	110/7206	7.64019939657e-25
ko04728	Dopaminergic synapse	70/756	185/7206	1.71820367781e-23
ko04727	GABAergic synapse	52/756	110/7206	5.51656897366e-23
ko04713	Circadian entrainment	56/756	136/7206	4.7929952881e-21
ko04723	Retrograde endocannabinoid signaling	63/756	175/7206	6.61977722381e-20
ko04024	cAMP signaling pathway	79/756	279/7206	1.83170368256e-17
ko04911	Insulin secretion	46/756	117/7206	1.5302919637e-16
ko04725	Cholinergic synapse	53/756	160/7206	3.90660572531e-15
ko04020	Calcium signaling pathway	68/756	265/7206	8.14958318838e-13
ko05031	Amphetamine addiction	34/756	91/7206	8.27418061431e-12
ko04726	Serotonergic synapse	43/756	137/7206	1.29303206598e-11
ko04721	Synaptic vesicle cycle	31/756	80/7206	2.31952946172e-11
ko04720	Long-term potentiation	35/756	99/7206	2.55402866244e-11
ko04921	Oxytocin signaling pathway	55/756	209/7206	4.43687059476e-11
ko04261	Adrenergic signaling in cardiomyocytes	54/756	205/7206	6.4506955671e-11
ko04742	Taste transduction	26/756	61/7206	7.8087374792e-11
ko05030	Cocaine addiction	27/756	73/7206	1.56532445801e-09
ko04010	MAPK signaling pathway	66/756	321/7206	6.17095169302e-08
ko05203	Viral carcinogenesis	6/756	277/7206	1.13300684974e-07
ko04744	Phototransduction	16/756	36/7206	1.78760802829e-07
ko04925	Aldosterone synthesis and secretion	30/756	105/7206	1.8097105777e-07
ko04970	Salivary secretion	28/756	95/7206	2.27761403299e-07
ko04060	Cytokine-cytokine receptor interaction	2/756	191/7206	2.4191243984e-07
ko04072	Phospholipase D signaling pathway	45/756	197/7206	3.48290645044e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	23/756	74/7206	9.7644362973e-07
ko04070	Phosphatidylinositol signaling system	29/756	112/7206	2.70943382416e-06
ko03040	Spliceosome	1/756	145/7206	3.1575564855e-06
ko04514	Cell adhesion molecules (CAMs)	32/756	130/7206	3.22549222119e-06
ko04022	cGMP-PKG signaling pathway	45/756	216/7206	4.70491329577e-06
ko04972	Pancreatic secretion	28/756	111/7206	1.10510625987e-05
ko04971	Gastric acid secretion	25/756	98/7206	1.73875292329e-05
ko05168	Herpes simplex infection	4/756	182/7206	2.38713151169e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/756	79/7206	4.19725294312e-05
ko04260	Cardiac muscle contraction	24/756	98/7206	7.02006032557e-05
ko04730	Long-term depression	20/756	78/7206	0.000110212315993
ko04740	Olfactory transduction	20/756	80/7206	0.000160656449528
ko04915	Estrogen signaling pathway	28/756	131/7206	0.000230680073566
ko04350	TGF-beta signaling pathway	1/756	103/7206	0.000256445072264
ko05414	Dilated cardiomyopathy	24/756	112/7206	0.000523127456463
ko05169	Epstein-Barr virus infection	8/756	206/7206	0.000732037287472
ko04110	Cell cycle	4/756	145/7206	0.000844940895279
ko04621	NOD-like receptor signaling pathway	5/756	157/7206	0.00091319368987
ko04745	Phototransduction - fly	11/756	38/7206	0.00132704630479
ko05322	Systemic lupus erythematosus	5/756	151/7206	0.00178241309244
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/756	14/7206	0.00187166018159
ko05164	Influenza A	6/756	167/7206	0.00189428936741
ko04540	Gap junction	25/756	128/7206	0.00193649014755
ko04630	Jak-STAT signaling pathway	4/756	132/7206	0.00231548179664
ko00562	Inositol phosphate metabolism	19/756	89/7206	0.00242509150606
ko04930	Type II diabetes mellitus	13/756	54/7206	0.00315684313934
ko04141	Protein processing in endoplasmic reticulum	8/756	184/7206	0.00332041483549
ko04924	Renin secretion	18/756	86/7206	0.00381474030802
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/756	59/7206	0.00397572868444
ko04612	Antigen processing and presentation	1/756	77/7206	0.00407076634574
ko05205	Proteoglycans in cancer	15/756	271/7206	0.00455421612793
ko03013	RNA transport	7/756	166/7206	0.00460915211471
ko04120	Ubiquitin mediated proteolysis	5/756	138/7206	0.00467511789304
ko04976	Bile secretion	17/756	80/7206	0.00473489421777
ko04360	Axon guidance	38/756	233/7206	0.00618505141578
ko00512	Mucin type O-glycan biosynthesis	8/756	29/7206	0.00818305148778
ko04964	Proximal tubule bicarbonate reclamation	8/756	29/7206	0.00818305148778
ko05034	Alcoholism	38/756	238/7206	0.00934440262675
ko04750	Inflammatory mediator regulation of TRP channels	22/756	122/7206	0.0104591021431
ko04064	NF-kappa B signaling pathway	3/756	96/7206	0.0115947579365
ko05410	Hypertrophic cardiomyopathy (HCM)	19/756	100/7206	0.0122378583137
ko04640	Hematopoietic cell lineage	1/756	64/7206	0.0125385464286
ko04371	Apelin signaling pathway	29/756	177/7206	0.0128544902823
ko04140	Autophagy - animal	8/756	164/7206	0.0139609148061
ko04550	Signaling pathways regulating pluripotency of stem cells	8/756	165/7206	0.0140113788375
ko03008	Ribosome biogenesis in eukaryotes	2/756	79/7206	0.015101811379
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/756	15/7206	0.0153738112915
ko04014	Ras signaling pathway	42/756	279/7206	0.0162532759295
ko00240	Pyrimidine metabolism	4/756	110/7206	0.017171081688
ko05010	Alzheimer's disease	32/756	202/7206	0.018996459874
ko04330	Notch signaling pathway	1/756	62/7206	0.0191882169889
ko04918	Thyroid hormone synthesis	16/756	86/7206	0.0201302429022
ko05140	Leishmaniasis	2/756	75/7206	0.0215056572998
ko04146	Peroxisome	3/756	89/7206	0.0226661271669
ko05162	Measles	5/756	120/7206	0.0227152518659
ko05161	Hepatitis B	9/756	173/7206	0.0227203133915
ko00480	Glutathione metabolism	1/756	55/7206	0.0267367202354
ko05321	Inflammatory bowel disease (IBD)	1/756	56/7206	0.0268166899637
ko04214	Apoptosis - fly	2/756	72/7206	0.0309775994297
ko03018	RNA degradation	3/756	84/7206	0.0314626742475
ko04670	Leukocyte transendothelial migration	8/756	151/7206	0.0316037362886
ko05231	Choline metabolism in cancer	22/756	134/7206	0.0316513132391
ko00310	Lysine degradation	2/756	73/7206	0.03169803149
ko04217	Necroptosis	10/756	178/7206	0.0341047031958
ko04015	Rap1 signaling pathway	40/756	278/7206	0.0357166897314
ko00513	Various types of N-glycan biosynthesis	9/756	42/7206	0.0368454617751
ko04973	Carbohydrate digestion and absorption	9/756	42/7206	0.0368454617751
ko00515	Mannose type O-glycan biosynthesis	6/756	25/7206	0.0406769102453
ko04062	Chemokine signaling pathway	30/756	201/7206	0.0462233945585
ko04966	Collecting duct acid secretion	6/756	26/7206	0.0483643294357
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/756	182/7206	0.0491873149558