ko pathway ratio_in_study ratio_in_pop p_value ko04621 NOD-like receptor signaling pathway 20/159 157/7206 1.63721002569e-10 ko04658 Th1 and Th2 cell differentiation 15/159 96/7206 2.06319167382e-09 ko04060 Cytokine-cytokine receptor interaction 20/159 191/7206 5.49440123609e-09 ko05162 Measles 16/159 120/7206 6.35858801654e-09 ko04380 Osteoclast differentiation 16/159 134/7206 3.19139344526e-08 ko04659 Th17 cell differentiation 14/159 106/7206 6.68674217208e-08 ko04660 T cell receptor signaling pathway 15/159 124/7206 7.38306224394e-08 ko05164 Influenza A 17/159 167/7206 1.26600243148e-07 ko04064 NF-kappa B signaling pathway 13/159 96/7206 1.49079412739e-07 ko04623 Cytosolic DNA-sensing pathway 9/159 41/7206 1.89234999872e-07 ko05161 Hepatitis B 17/159 173/7206 2.12139286296e-07 ko04620 Toll-like receptor signaling pathway 13/159 100/7206 2.43347275659e-07 ko04668 TNF signaling pathway 14/159 120/7206 3.24273089403e-07 ko04662 B cell receptor signaling pathway 12/159 88/7206 4.24150713361e-07 ko05168 Herpes simplex infection 17/159 182/7206 4.4128842167e-07 ko05167 Kaposi's sarcoma-associated herpesvirus infection 16/159 191/7206 4.16617062505e-06 ko05160 Hepatitis C 14/159 153/7206 6.17990408355e-06 ko04622 RIG-I-like receptor signaling pathway 9/159 62/7206 7.37246757432e-06 ko04217 Necroptosis 14/159 178/7206 3.48754833591e-05 ko04210 Apoptosis 14/159 180/7206 3.94901789422e-05 ko05166 HTLV-I infection 18/159 292/7206 7.02847364147e-05 ko05145 Toxoplasmosis 11/159 126/7206 9.74533163419e-05 ko04630 Jak-STAT signaling pathway 11/159 132/7206 0.000148164088572 ko05169 Epstein-Barr virus infection 14/159 206/7206 0.000170049161652 ko05321 Inflammatory bowel disease (IBD) 7/159 56/7206 0.000208641149194 ko05140 Leishmaniasis 8/159 75/7206 0.000226696493177 ko05152 Tuberculosis 13/159 187/7206 0.000233741421467 ko04650 Natural killer cell mediated cytotoxicity 9/159 97/7206 0.000268857588854 ko05131 Shigellosis 8/159 82/7206 0.000420358953216 ko05340 Primary immunodeficiency 5/159 30/7206 0.000447836581629 ko04611 Platelet activation 11/159 163/7206 0.000911454660301 ko05150 Staphylococcus aureus infection 5/159 36/7206 0.00106492575261 ko04672 Intestinal immune network for IgA production 5/159 37/7206 0.00120967120557 ko04062 Chemokine signaling pathway 12/159 201/7206 0.00156545596594 ko05142 Chagas disease (American trypanosomiasis) 9/159 130/7206 0.00223268335773 ko05215 Prostate cancer 8/159 111/7206 0.00303955683642 ko05323 Rheumatoid arthritis 7/159 89/7206 0.00337938941736 ko05212 Pancreatic cancer 6/159 83/7206 0.00979592443829 ko05220 Chronic myeloid leukemia 6/159 85/7206 0.0109513581591 ko04657 IL-17 signaling pathway 6/159 87/7206 0.0122002788575 ko04920 Adipocytokine signaling pathway 6/159 89/7206 0.0135463638914 ko05330 Allograft rejection 3/159 24/7206 0.0151858761414 ko05120 Epithelial cell signaling in Helicobacter pylori infection 6/159 92/7206 0.0157554624728 ko04810 Regulation of actin cytoskeleton 12/159 264/7206 0.0160744970967 ko04010 MAPK signaling pathway 14/159 321/7206 0.0168157025391 ko05144 Malaria 4/159 45/7206 0.0168533159844 ko04666 Fc gamma R-mediated phagocytosis 7/159 122/7206 0.018014795131 ko00511 Other glycan degradation 3/159 26/7206 0.0188928748502 ko04624 Toll and Imd signaling pathway 4/159 49/7206 0.0224030598172 ko05134 Legionellosis 5/159 74/7206 0.0233388344601 ko05320 Autoimmune thyroid disease 3/159 29/7206 0.0253101702744 ko04933 AGE-RAGE signaling pathway in diabetic complications 7/159 135/7206 0.0294373498189 ko04610 Complement and coagulation cascades 5/159 79/7206 0.0299380149223 ko05416 Viral myocarditis 4/159 55/7206 0.0326055730701 ko04917 Prolactin signaling pathway 5/159 87/7206 0.0427412984887 ko05133 Pertussis 5/159 87/7206 0.0427412984887 ko00073 Cutin, suberine and wax biosynthesis 1/159 2/7206 0.043646024797 ko04670 Leukocyte transendothelial migration 7/159 151/7206 0.0491961091676