ko pathway ratio_in_study ratio_in_pop p_value ko04070 Phosphatidylinositol signaling system 10/121 112/7206 1.64038070579e-05 ko00051 Fructose and mannose metabolism 6/121 42/7206 6.33493718478e-05 ko00010 Glycolysis / Gluconeogenesis 7/121 74/7206 0.000224316977709 ko00680 Methane metabolism 5/121 34/7206 0.000231535910185 ko01200 Carbon metabolism 8/121 128/7206 0.00133618856646 ko00030 Pentose phosphate pathway 4/121 32/7206 0.00189102054761 ko04726 Serotonergic synapse 8/121 137/7206 0.00206112578963 ko05230 Central carbon metabolism in cancer 6/121 81/7206 0.00230268692541 ko04014 Ras signaling pathway 12/121 279/7206 0.00242256096874 ko01230 Biosynthesis of amino acids 6/121 85/7206 0.00293920145914 ko02010 ABC transporters 4/121 39/7206 0.00395204415256 ko04152 AMPK signaling pathway 8/121 161/7206 0.00554716519155 ko04710 Circadian rhythm 4/121 43/7206 0.00563242847946 ko00564 Glycerophospholipid metabolism 6/121 99/7206 0.00623040620921 ko05032 Morphine addiction 6/121 110/7206 0.0102667382481 ko04724 Glutamatergic synapse 7/121 152/7206 0.0137934297342 ko00562 Inositol phosphate metabolism 5/121 89/7206 0.0166388690116 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/121 1/7206 0.0167915625868 ko04744 Phototransduction 3/121 36/7206 0.0220425618905 ko04921 Oxytocin signaling pathway 8/121 209/7206 0.0240411499008 ko04720 Long-term potentiation 5/121 99/7206 0.0251463292754 ko04745 Phototransduction - fly 3/121 38/7206 0.0254236880286 ko04931 Insulin resistance 6/121 137/7206 0.0274228354584 ko04925 Aldosterone synthesis and secretion 5/121 105/7206 0.0313878360776 ko04919 Thyroid hormone signaling pathway 6/121 143/7206 0.0328907067044 ko04728 Dopaminergic synapse 7/121 185/7206 0.0357473985532 ko04727 GABAergic synapse 5/121 110/7206 0.0372726788734 ko04142 Lysosome 6/121 151/7206 0.0412218011641 ko00230 Purine metabolism 7/121 194/7206 0.0443784794711 ko04072 Phospholipase D signaling pathway 7/121 197/7206 0.0475310070473