ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	75/771	152/7206	8.16702757213e-34
ko04080	Neuroactive ligand-receptor interaction	133/771	423/7206	1.31400787369e-33
ko05033	Nicotine addiction	41/771	56/7206	2.04743704641e-28
ko05032	Morphine addiction	54/771	110/7206	2.01867138497e-24
ko04713	Circadian entrainment	59/771	136/7206	4.40383464633e-23
ko04728	Dopaminergic synapse	70/771	185/7206	5.57188793775e-23
ko04727	GABAergic synapse	52/771	110/7206	1.39115047966e-22
ko04024	cAMP signaling pathway	84/771	279/7206	7.78993948501e-20
ko04723	Retrograde endocannabinoid signaling	63/771	175/7206	1.86080005235e-19
ko04721	Synaptic vesicle cycle	39/771	80/7206	8.23727795532e-18
ko04725	Cholinergic synapse	57/771	160/7206	1.87007925655e-17
ko04911	Insulin secretion	43/771	117/7206	5.31732925304e-14
ko04261	Adrenergic signaling in cardiomyocytes	59/771	205/7206	3.02707177577e-13
ko04726	Serotonergic synapse	45/771	137/7206	1.41721032099e-12
ko04921	Oxytocin signaling pathway	58/771	209/7206	2.640819935e-12
ko05031	Amphetamine addiction	35/771	91/7206	2.68306406794e-12
ko04720	Long-term potentiation	36/771	99/7206	9.07620288523e-12
ko04742	Taste transduction	27/771	61/7206	1.81183696542e-11
ko04020	Calcium signaling pathway	66/771	265/7206	1.88149582811e-11
ko05030	Cocaine addiction	26/771	73/7206	1.21116586188e-08
ko04010	MAPK signaling pathway	68/771	321/7206	1.70233265672e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	25/771	74/7206	7.75729844359e-08
ko04970	Salivary secretion	29/771	95/7206	9.10357839784e-08
ko04925	Aldosterone synthesis and secretion	30/771	105/7206	2.79229187432e-07
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/771	79/7206	1.29483867511e-06
ko03040	Spliceosome	1/771	145/7206	2.0228631424e-06
ko04060	Cytokine-cytokine receptor interaction	4/771	191/7206	7.82788674235e-06
ko04260	Cardiac muscle contraction	26/771	98/7206	7.84348503152e-06
ko04971	Gastric acid secretion	26/771	98/7206	7.84348503152e-06
ko04072	Phospholipase D signaling pathway	42/771	197/7206	1.01935179496e-05
ko04972	Pancreatic secretion	28/771	111/7206	1.32805289879e-05
ko05203	Viral carcinogenesis	10/771	277/7206	1.67017994759e-05
ko04514	Cell adhesion molecules (CAMs)	31/771	130/7206	1.78412604102e-05
ko04744	Phototransduction	13/771	36/7206	4.82060261696e-05
ko05164	Influenza A	4/771	167/7206	6.94482179405e-05
ko04360	Axon guidance	45/771	233/7206	8.3491327153e-05
ko04022	cGMP-PKG signaling pathway	42/771	216/7206	0.000115386303175
ko04730	Long-term depression	20/771	78/7206	0.000144687458918
ko04966	Collecting duct acid secretion	10/771	26/7206	0.000198749338802
ko05414	Dilated cardiomyopathy	25/771	112/7206	0.000292819942298
ko03013	RNA transport	5/771	166/7206	0.000328020706212
ko05168	Herpes simplex infection	6/771	182/7206	0.000360100609566
ko04745	Phototransduction - fly	12/771	38/7206	0.000401362443954
ko05322	Systemic lupus erythematosus	4/771	151/7206	0.000428628958547
ko04740	Olfactory transduction	19/771	80/7206	0.000713888466985
ko04621	NOD-like receptor signaling pathway	5/771	157/7206	0.000927173308425
ko04070	Phosphatidylinositol signaling system	24/771	112/7206	0.000928202805166
ko04141	Protein processing in endoplasmic reticulum	7/771	184/7206	0.000983646023339
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/771	59/7206	0.00105330383676
ko04350	TGF-beta signaling pathway	2/771	103/7206	0.00116118646306
ko04120	Ubiquitin mediated proteolysis	4/771	138/7206	0.00117175330039
ko04014	Ras signaling pathway	47/771	279/7206	0.00145671579895
ko04915	Estrogen signaling pathway	26/771	131/7206	0.00153195520327
ko04750	Inflammatory mediator regulation of TRP channels	25/771	122/7206	0.00156344471597
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/771	14/7206	0.00207435482682
ko04964	Proximal tubule bicarbonate reclamation	9/771	29/7206	0.0024323109011
ko04612	Antigen processing and presentation	1/771	77/7206	0.00263301112893
ko03008	Ribosome biogenesis in eukaryotes	1/771	79/7206	0.00270976635549
ko00240	Pyrimidine metabolism	3/771	110/7206	0.00289861627051
ko05110	Vibrio cholerae infection	15/771	63/7206	0.00292355499056
ko04540	Gap junction	25/771	128/7206	0.00337473591533
ko04722	Neurotrophin signaling pathway	29/771	160/7206	0.00408064997313
ko04924	Renin secretion	18/771	86/7206	0.00441038735532
ko05162	Measles	4/771	120/7206	0.00447042227616
ko05410	Hypertrophic cardiomyopathy (HCM)	20/771	100/7206	0.00502347778893
ko04146	Peroxisome	2/771	89/7206	0.00508795531076
ko04930	Type II diabetes mellitus	13/771	54/7206	0.00591602528016
ko04110	Cell cycle	6/771	145/7206	0.00633128076628
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/771	182/7206	0.00742755132471
ko05169	Epstein-Barr virus infection	11/771	206/7206	0.00838290010347
ko04626	Plant-pathogen interaction	6/771	18/7206	0.00882391664515
ko04071	Sphingolipid signaling pathway	28/771	162/7206	0.00962271524807
ko05034	Alcoholism	38/771	238/7206	0.0102795477038
ko04973	Carbohydrate digestion and absorption	10/771	42/7206	0.0113444367062
ko04064	NF-kappa B signaling pathway	3/771	96/7206	0.0116113749032
ko04640	Hematopoietic cell lineage	1/771	64/7206	0.0127639377282
ko04371	Apelin signaling pathway	29/771	177/7206	0.018617414137
ko00330	Arginine and proline metabolism	1/771	61/7206	0.0191981240378
ko04214	Apoptosis - fly	2/771	72/7206	0.0212646190947
ko04630	Jak-STAT signaling pathway	6/771	132/7206	0.0216089821599
ko05140	Leishmaniasis	2/771	75/7206	0.0219319366399
ko05231	Choline metabolism in cancer	23/771	134/7206	0.0226579793965
ko04666	Fc gamma R-mediated phagocytosis	21/771	122/7206	0.0256993635549
ko04217	Necroptosis	10/771	178/7206	0.0262100581039
ko00480	Glutathione metabolism	1/771	55/7206	0.0266761281609
ko05205	Proteoglycans in cancer	18/771	271/7206	0.0270705188325
ko04976	Bile secretion	15/771	80/7206	0.0273873729879
ko04015	Rap1 signaling pathway	41/771	278/7206	0.0294482952433
ko03320	PPAR signaling pathway	2/771	69/7206	0.0302194037768
ko03018	RNA degradation	3/771	84/7206	0.0314922516344
ko05161	Hepatitis B	10/771	173/7206	0.0335597465987
ko05120	Epithelial cell signaling in Helicobacter pylori infection	16/771	92/7206	0.0419813795885
ko04510	Focal adhesion	16/771	240/7206	0.0427960804092
ko04210	Apoptosis	11/771	180/7206	0.0494579718883