ko pathway ratio_in_study ratio_in_pop p_value ko04360 Axon guidance 46/389 233/7206 4.9026211618e-15 ko05033 Nicotine addiction 19/389 56/7206 3.56039145761e-11 ko04727 GABAergic synapse 20/389 110/7206 1.3308164999e-06 ko04721 Synaptic vesicle cycle 16/389 80/7206 4.26614932864e-06 ko04391 Hippo signaling pathway - fly 17/389 90/7206 4.86988504237e-06 ko04514 Cell adhesion molecules (CAMs) 20/389 130/7206 1.86305735762e-05 ko05032 Morphine addiction 18/389 110/7206 2.07290402484e-05 ko04723 Retrograde endocannabinoid signaling 23/389 175/7206 6.02339387075e-05 ko04728 Dopaminergic synapse 24/389 185/7206 8.19348397287e-05 ko00604 Glycosphingolipid biosynthesis - ganglio series 5/389 14/7206 0.000596165964319 ko04550 Signaling pathways regulating pluripotency of stem cells 20/389 165/7206 0.000631774980545 ko04724 Glutamatergic synapse 19/389 152/7206 0.000698305265884 ko04950 Maturity onset diabetes of the young 7/389 29/7206 0.00070142987547 ko03013 RNA transport 1/389 166/7206 0.00153838010138 ko04024 cAMP signaling pathway 28/389 279/7206 0.00158595571406 ko05210 Colorectal cancer 12/389 86/7206 0.00209590713189 ko04611 Platelet activation 1/389 163/7206 0.00230203865346 ko05217 Basal cell carcinoma 10/389 68/7206 0.00327506998113 ko04520 Adherens junction 13/389 103/7206 0.00344963422415 ko05203 Viral carcinogenesis 5/389 277/7206 0.00401971005875 ko04010 MAPK signaling pathway 29/389 321/7206 0.00528772472528 ko05030 Cocaine addiction 10/389 73/7206 0.00550959001329 ko05014 Amyotrophic lateral sclerosis (ALS) 10/389 74/7206 0.00607333552413 ko04725 Cholinergic synapse 17/389 160/7206 0.00686577944521 ko05202 Transcriptional misregulation in cancer 19/389 188/7206 0.00785186428067 ko04911 Insulin secretion 13/389 117/7206 0.011539518722 ko04340 Hedgehog signaling pathway 8/389 58/7206 0.0120151299498 ko04060 Cytokine-cytokine receptor interaction 3/389 191/7206 0.0136427212472 ko05016 Huntington's disease 4/389 215/7206 0.0138116963014 ko05322 Systemic lupus erythematosus 2/389 151/7206 0.0173439655889 ko05012 Parkinson's disease 2/389 155/7206 0.0176850736329 ko04020 Calcium signaling pathway 6/389 265/7206 0.0177731842011 ko04964 Proximal tubule bicarbonate reclamation 5/389 29/7206 0.0181482006896 ko04141 Protein processing in endoplasmic reticulum 3/389 184/7206 0.0190105799981 ko04713 Circadian entrainment 14/389 136/7206 0.0190730916412 ko03040 Spliceosome 2/389 145/7206 0.0245012698716 ko05169 Epstein-Barr virus infection 4/389 206/7206 0.0265560427895 ko04310 Wnt signaling pathway 17/389 181/7206 0.0278968200866 ko04390 Hippo signaling pathway 17/389 188/7206 0.0324393872331 ko04120 Ubiquitin mediated proteolysis 2/389 138/7206 0.0344857015955 ko04530 Tight junction 20/389 228/7206 0.0349966708253 ko05164 Influenza A 3/389 167/7206 0.0356443303537 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 9/389 79/7206 0.0379185695996 ko04961 Endocrine and other factor-regulated calcium reabsorption 7/389 59/7206 0.0384212714933 ko05132 Salmonella infection 10/389 98/7206 0.0421534211034 ko00564 Glycerophospholipid metabolism 1/389 99/7206 0.0438757196953 ko04621 NOD-like receptor signaling pathway 3/389 157/7206 0.0483888123847 ko04630 Jak-STAT signaling pathway 2/389 132/7206 0.0487611089954 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 4/389 26/7206 0.0487642039905