ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	133/908	423/7206	7.37069374034e-26
ko05033	Nicotine addiction	41/908	56/7206	1.44244928369e-25
ko04724	Glutamatergic synapse	66/908	152/7206	1.16784596871e-21
ko04727	GABAergic synapse	51/908	110/7206	1.71234856344e-18
ko05032	Morphine addiction	47/908	110/7206	2.05324370301e-15
ko04721	Synaptic vesicle cycle	38/908	80/7206	1.61154337638e-14
ko04713	Circadian entrainment	51/908	136/7206	7.39500990699e-14
ko04728	Dopaminergic synapse	61/908	185/7206	2.24066432179e-13
ko04725	Cholinergic synapse	54/908	160/7206	1.96165850495e-12
ko04723	Retrograde endocannabinoid signaling	57/908	175/7206	2.51346176311e-12
ko04744	Phototransduction	22/908	36/7206	8.47275408321e-12
ko04024	cAMP signaling pathway	76/908	279/7206	1.78974296822e-11
ko04911	Insulin secretion	42/908	117/7206	6.39831657712e-11
ko04742	Taste transduction	27/908	61/7206	7.99302017512e-10
ko05203	Viral carcinogenesis	7/908	277/7206	2.75332557317e-09
ko04740	Olfactory transduction	30/908	80/7206	1.09911265877e-08
ko04514	Cell adhesion molecules (CAMs)	40/908	130/7206	5.17046871698e-08
ko04726	Serotonergic synapse	41/908	137/7206	5.75753265102e-08
ko03040	Spliceosome	1/908	145/7206	9.1187545625e-08
ko04261	Adrenergic signaling in cardiomyocytes	53/908	205/7206	1.61466393451e-07
ko04974	Protein digestion and absorption	31/908	96/7206	3.35376076369e-07
ko05030	Cocaine addiction	25/908	73/7206	1.35645139244e-06
ko04120	Ubiquitin mediated proteolysis	2/908	138/7206	3.15297344251e-06
ko05168	Herpes simplex infection	5/908	182/7206	4.03385661688e-06
ko05164	Influenza A	4/908	167/7206	4.61468394736e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	24/908	74/7206	6.52912960855e-06
ko05166	HTLV-I infection	14/908	292/7206	8.17181833722e-06
ko05031	Amphetamine addiction	27/908	91/7206	1.58955432272e-05
ko04964	Proximal tubule bicarbonate reclamation	13/908	29/7206	1.79825939207e-05
ko05162	Measles	2/908	120/7206	2.21330041623e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/908	79/7206	2.26772551509e-05
ko03013	RNA transport	5/908	166/7206	2.49417498007e-05
ko04970	Salivary secretion	27/908	95/7206	2.98408552579e-05
ko04921	Oxytocin signaling pathway	47/908	209/7206	4.95765105829e-05
ko04512	ECM-receptor interaction	23/908	79/7206	9.2884795262e-05
ko05322	Systemic lupus erythematosus	5/908	151/7206	0.000102171052232
ko04976	Bile secretion	23/908	80/7206	0.000106878218253
ko04010	MAPK signaling pathway	64/908	321/7206	0.000137741023167
ko04260	Cardiac muscle contraction	26/908	98/7206	0.000161778183121
ko04621	NOD-like receptor signaling pathway	6/908	157/7206	0.000226528363099
ko04020	Calcium signaling pathway	54/908	265/7206	0.000299105430529
ko04137	Mitophagy - animal	1/908	82/7206	0.000326074519393
ko04360	Axon guidance	48/908	233/7206	0.000415767411761
ko03008	Ribosome biogenesis in eukaryotes	1/908	79/7206	0.000487987318292
ko05169	Epstein-Barr virus infection	11/908	206/7206	0.000614235265992
ko04730	Long-term depression	21/908	78/7206	0.000791079439584
ko04060	Cytokine-cytokine receptor interaction	10/908	191/7206	0.000855577192999
ko04214	Apoptosis - fly	1/908	72/7206	0.00108144465439
ko04720	Long-term potentiation	24/908	99/7206	0.00118488946664
ko04218	Cellular senescence	9/908	177/7206	0.00119571247029
ko04141	Protein processing in endoplasmic reticulum	10/908	184/7206	0.00154749535439
ko05161	Hepatitis B	9/908	173/7206	0.00160913700816
ko05205	Proteoglycans in cancer	18/908	271/7206	0.0019401424444
ko04022	cGMP-PKG signaling pathway	43/908	216/7206	0.00233693363684
ko03018	RNA degradation	2/908	84/7206	0.00234399262558
ko04978	Mineral absorption	12/908	40/7206	0.00285375834672
ko04971	Gastric acid secretion	23/908	98/7206	0.00301962364557
ko04610	Complement and coagulation cascades	2/908	79/7206	0.00323066947033
ko04972	Pancreatic secretion	25/908	111/7206	0.00344809777656
ko04611	Platelet activation	9/908	163/7206	0.00390619929736
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/908	182/7206	0.00455017560633
ko05140	Leishmaniasis	2/908	75/7206	0.00465260898281
ko04612	Antigen processing and presentation	2/908	77/7206	0.00483460142373
ko04924	Renin secretion	20/908	86/7206	0.00510378246854
ko00564	Glycerophospholipid metabolism	4/908	99/7206	0.00574713943295
ko04110	Cell cycle	8/908	145/7206	0.00742466053045
ko04151	PI3K-Akt signaling pathway	67/908	390/7206	0.00744191271873
ko05220	Chronic myeloid leukemia	3/908	85/7206	0.0076762116914
ko04668	TNF signaling pathway	6/908	120/7206	0.00799942088558
ko04064	NF-kappa B signaling pathway	4/908	96/7206	0.00801903392119
ko04217	Necroptosis	11/908	178/7206	0.00802773383548
ko04140	Autophagy - animal	10/908	164/7206	0.008511163429
ko05016	Huntington's disease	15/908	215/7206	0.00897556934997
ko04150	mTOR signaling pathway	12/908	184/7206	0.00936277961667
ko00280	Valine, leucine and isoleucine degradation	1/908	54/7206	0.0117563683582
ko00520	Amino sugar and nucleotide sugar metabolism	1/908	55/7206	0.0121844577982
ko04660	T cell receptor signaling pathway	7/908	124/7206	0.0139367361765
ko05414	Dilated cardiomyopathy	23/908	112/7206	0.0145482840277
ko04540	Gap junction	26/908	128/7206	0.0145569001168
ko05410	Hypertrophic cardiomyopathy (HCM)	21/908	100/7206	0.0149361981351
ko04146	Peroxisome	4/908	89/7206	0.0154449161204
ko04014	Ras signaling pathway	49/908	279/7206	0.0162905474259
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/908	59/7206	0.0163226024684
ko04925	Aldosterone synthesis and secretion	22/908	105/7206	0.0164696549629
ko00380	Tryptophan metabolism	1/908	50/7206	0.0170991636743
ko00240	Pyrimidine metabolism	6/908	110/7206	0.019811729156
ko04930	Type II diabetes mellitus	13/908	54/7206	0.0205436754414
ko04640	Hematopoietic cell lineage	2/908	64/7206	0.0208385218358
ko04657	IL-17 signaling pathway	4/908	87/7206	0.0215381658914
ko04745	Phototransduction - fly	10/908	38/7206	0.0224675856219
ko04142	Lysosome	10/908	151/7206	0.024871636296
ko03420	Nucleotide excision repair	1/908	46/7206	0.0250871554163
ko04659	Th17 cell differentiation	6/908	106/7206	0.0265270650667
ko04658	Th1 and Th2 cell differentiation	5/908	96/7206	0.0286148588272
ko01212	Fatty acid metabolism	2/908	60/7206	0.0291882197536
ko05131	Shigellosis	4/908	82/7206	0.0293072328829
ko00330	Arginine and proline metabolism	2/908	61/7206	0.0300709505217
ko04973	Carbohydrate digestion and absorption	10/908	42/7206	0.0359011802889
ko05012	Parkinson's disease	11/908	155/7206	0.0368557750403
ko03022	Basal transcription factors	1/908	44/7206	0.0373441091943
ko04966	Collecting duct acid secretion	7/908	26/7206	0.0374970260229
ko00071	Fatty acid degradation	1/908	45/7206	0.0384238521152
ko04138	Autophagy - yeast	4/908	81/7206	0.0410543371358
ko03320	PPAR signaling pathway	3/908	69/7206	0.0423067300248
ko05215	Prostate cancer	7/908	111/7206	0.0430633690514
ko04630	Jak-STAT signaling pathway	9/908	132/7206	0.0460126645456