ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	68/712	152/7206	1.36842853439e-29
ko04080	Neuroactive ligand-receptor interaction	117/712	423/7206	3.88588284978e-27
ko05032	Morphine addiction	53/712	110/7206	3.58152909275e-25
ko05033	Nicotine addiction	37/712	56/7206	1.85369903552e-24
ko04727	GABAergic synapse	50/712	110/7206	2.2963074906e-22
ko04723	Retrograde endocannabinoid signaling	63/712	175/7206	2.7113966512e-21
ko04713	Circadian entrainment	53/712	136/7206	7.08445621152e-20
ko04728	Dopaminergic synapse	58/712	185/7206	1.95705885515e-16
ko04721	Synaptic vesicle cycle	36/712	80/7206	3.00719503232e-16
ko04024	cAMP signaling pathway	73/712	279/7206	1.30107177822e-15
ko04725	Cholinergic synapse	51/712	160/7206	6.56913959862e-15
ko04911	Insulin secretion	41/712	117/7206	8.94219459935e-14
ko04726	Serotonergic synapse	44/712	137/7206	3.74737140409e-13
ko04744	Phototransduction	21/712	36/7206	7.80955724753e-13
ko04921	Oxytocin signaling pathway	56/712	209/7206	1.1407953196e-12
ko04020	Calcium signaling pathway	65/712	265/7206	1.98227164452e-12
ko04261	Adrenergic signaling in cardiomyocytes	51/712	205/7206	2.34049897228e-10
ko04742	Taste transduction	24/712	61/7206	8.84070068025e-10
ko04720	Long-term potentiation	30/712	99/7206	1.05057320785e-08
ko05031	Amphetamine addiction	27/712	91/7206	9.39563193295e-08
ko05203	Viral carcinogenesis	6/712	277/7206	5.15652611848e-07
ko04970	Salivary secretion	26/712	95/7206	9.32571424246e-07
ko04010	MAPK signaling pathway	59/712	321/7206	1.93265490496e-06
ko05030	Cocaine addiction	21/712	73/7206	4.37590024324e-06
ko05322	Systemic lupus erythematosus	1/712	151/7206	5.23632588601e-06
ko04260	Cardiac muscle contraction	25/712	98/7206	6.05777931589e-06
ko04972	Pancreatic secretion	27/712	111/7206	6.84446022266e-06
ko04022	cGMP-PKG signaling pathway	43/712	216/7206	6.94786657179e-06
ko04925	Aldosterone synthesis and secretion	26/712	105/7206	7.14157464554e-06
ko03040	Spliceosome	1/712	145/7206	7.36471692774e-06
ko04070	Phosphatidylinositol signaling system	27/712	112/7206	8.19201716483e-06
ko05164	Influenza A	2/712	167/7206	8.94565619095e-06
ko04730	Long-term depression	21/712	78/7206	1.36830072883e-05
ko04072	Phospholipase D signaling pathway	39/712	197/7206	1.73488028216e-05
ko04060	Cytokine-cytokine receptor interaction	4/712	191/7206	3.62930990625e-05
ko03013	RNA transport	3/712	166/7206	5.79487334615e-05
ko05162	Measles	1/712	120/7206	8.01890313879e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/712	79/7206	0.000183042268169
ko05169	Epstein-Barr virus infection	6/712	206/7206	0.000195785193898
ko04740	Olfactory transduction	19/712	80/7206	0.000218343400474
ko05168	Herpes simplex infection	5/712	182/7206	0.000349753672727
ko04110	Cell cycle	3/712	145/7206	0.000358755423125
ko04971	Gastric acid secretion	21/712	98/7206	0.00050791156763
ko04966	Collecting duct acid secretion	9/712	26/7206	0.000567379594862
ko04120	Ubiquitin mediated proteolysis	3/712	138/7206	0.000747828519208
ko04745	Phototransduction - fly	11/712	38/7206	0.000803961101015
ko04514	Cell adhesion molecules (CAMs)	25/712	130/7206	0.000944357372494
ko05110	Vibrio cholerae infection	15/712	63/7206	0.000957561400967
ko05014	Amyotrophic lateral sclerosis (ALS)	17/712	74/7206	0.00113314443772
ko04510	Focal adhesion	10/712	240/7206	0.00131250409232
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/712	14/7206	0.00136476540785
ko05215	Prostate cancer	2/712	111/7206	0.00185636874093
ko05414	Dilated cardiomyopathy	22/712	112/7206	0.00193093357285
ko05205	Proteoglycans in cancer	13/712	271/7206	0.00252844677656
ko04621	NOD-like receptor signaling pathway	5/712	157/7206	0.00257546610795
ko05161	Hepatitis B	6/712	173/7206	0.00266794405772
ko04550	Signaling pathways regulating pluripotency of stem cells	6/712	165/7206	0.00352830499158
ko05166	HTLV-I infection	15/712	292/7206	0.0036033855091
ko04141	Protein processing in endoplasmic reticulum	7/712	184/7206	0.00360477217809
ko04630	Jak-STAT signaling pathway	4/712	132/7206	0.00465328410954
ko04964	Proximal tubule bicarbonate reclamation	8/712	29/7206	0.00570655760389
ko05410	Hypertrophic cardiomyopathy (HCM)	19/712	100/7206	0.00583518414576
ko05140	Leishmaniasis	1/712	75/7206	0.0059233296931
ko05224	Breast cancer	7/712	174/7206	0.00642130049496
ko00562	Inositol phosphate metabolism	17/712	89/7206	0.00662864000333
ko04371	Apelin signaling pathway	29/712	177/7206	0.00678668028425
ko04915	Estrogen signaling pathway	23/712	131/7206	0.00694013911764
ko04710	Circadian rhythm	10/712	43/7206	0.00781599458867
ko04810	Regulation of actin cytoskeleton	14/712	264/7206	0.00843671602029
ko04540	Gap junction	22/712	128/7206	0.0100183845859
ko04924	Renin secretion	16/712	86/7206	0.0105289251213
ko04350	TGF-beta signaling pathway	3/712	103/7206	0.0118505745851
ko04750	Inflammatory mediator regulation of TRP channels	21/712	122/7206	0.0130283949046
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/712	59/7206	0.0134896652721
ko00680	Methane metabolism	8/712	34/7206	0.0155377741714
ko04930	Type II diabetes mellitus	11/712	54/7206	0.0184578356453
ko04640	Hematopoietic cell lineage	1/712	64/7206	0.0187788158968
ko04064	NF-kappa B signaling pathway	3/712	96/7206	0.0234217890829
ko04014	Ras signaling pathway	39/712	279/7206	0.0239881413145
ko04626	Plant-pathogen interaction	5/712	18/7206	0.0267439647111
ko04330	Notch signaling pathway	1/712	62/7206	0.0287974386972
ko05130	Pathogenic Escherichia coli infection	2/712	77/7206	0.0318416470304
ko04976	Bile secretion	14/712	80/7206	0.0350256327093
ko00230	Purine metabolism	28/712	194/7206	0.0375280157294
ko00280	Valine, leucine and isoleucine degradation	1/712	54/7206	0.0396701690649
ko00480	Glutathione metabolism	1/712	55/7206	0.0396807109589
ko05416	Viral myocarditis	1/712	55/7206	0.0396807109589
ko04620	Toll-like receptor signaling pathway	4/712	100/7206	0.0429034157002
ko05218	Melanoma	3/712	85/7206	0.0441771950938
ko05220	Chronic myeloid leukemia	3/712	85/7206	0.0441771950938
ko04214	Apoptosis - fly	2/712	72/7206	0.0443153146481
ko04657	IL-17 signaling pathway	3/712	87/7206	0.0446230678702
ko05133	Pertussis	3/712	87/7206	0.0446230678702
ko00310	Lysine degradation	2/712	73/7206	0.0451521777092
ko05034	Alcoholism	33/712	238/7206	0.0457795439868