ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	127/757	423/7206	1.20627917423e-30
ko04724	Glutamatergic synapse	68/757	152/7206	6.07435997146e-28
ko05033	Nicotine addiction	40/757	56/7206	2.25504080547e-27
ko05032	Morphine addiction	51/757	110/7206	4.70903241414e-22
ko04727	GABAergic synapse	49/757	110/7206	2.70601887694e-20
ko04024	cAMP signaling pathway	81/757	279/7206	1.4116601157e-18
ko04728	Dopaminergic synapse	62/757	185/7206	8.82172210326e-18
ko04723	Retrograde endocannabinoid signaling	59/757	175/7206	4.1506243635e-17
ko04713	Circadian entrainment	50/757	136/7206	1.99976997864e-16
ko04725	Cholinergic synapse	54/757	160/7206	9.01711328158e-16
ko04911	Insulin secretion	42/757	117/7206	1.42625077811e-13
ko04020	Calcium signaling pathway	67/757	265/7206	2.49533649322e-12
ko04721	Synaptic vesicle cycle	32/757	80/7206	4.12626909073e-12
ko04261	Adrenergic signaling in cardiomyocytes	56/757	205/7206	6.07595418175e-12
ko04726	Serotonergic synapse	42/757	137/7206	5.49759809635e-11
ko04921	Oxytocin signaling pathway	54/757	209/7206	2.0891127601e-10
ko04742	Taste transduction	25/757	61/7206	5.15152042124e-10
ko04720	Long-term potentiation	31/757	99/7206	1.08101419399e-08
ko05031	Amphetamine addiction	29/757	91/7206	2.07764240445e-08
ko04744	Phototransduction	17/757	36/7206	2.43044242314e-08
ko04010	MAPK signaling pathway	66/757	321/7206	6.27382035075e-08
ko04360	Axon guidance	51/757	233/7206	3.06222846542e-07
ko05030	Cocaine addiction	23/757	73/7206	7.63227342934e-07
ko04514	Cell adhesion molecules (CAMs)	33/757	130/7206	1.41038953558e-06
ko05203	Viral carcinogenesis	8/757	277/7206	1.95055765375e-06
ko04925	Aldosterone synthesis and secretion	28/757	105/7206	2.20062127242e-06
ko03040	Spliceosome	1/757	145/7206	3.1715177111e-06
ko04022	cGMP-PKG signaling pathway	45/757	216/7206	4.83608932651e-06
ko04970	Salivary secretion	25/757	95/7206	9.89338440094e-06
ko04060	Cytokine-cytokine receptor interaction	4/757	191/7206	1.15348392557e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/757	79/7206	1.26795493654e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	20/757	74/7206	5.01329621657e-05
ko04072	Phospholipase D signaling pathway	39/757	197/7206	7.96414360097e-05
ko05164	Influenza A	4/757	167/7206	0.000100753375002
ko04730	Long-term depression	20/757	78/7206	0.000112258799005
ko04260	Cardiac muscle contraction	23/757	98/7206	0.000170585739571
ko04971	Gastric acid secretion	23/757	98/7206	0.000170585739571
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/757	14/7206	0.000242855121526
ko05322	Systemic lupus erythematosus	4/757	151/7206	0.000413445106153
ko03013	RNA transport	5/757	166/7206	0.000466394544561
ko04972	Pancreatic secretion	24/757	111/7206	0.000474848623941
ko05168	Herpes simplex infection	6/757	182/7206	0.000511255050671
ko05414	Dilated cardiomyopathy	24/757	112/7206	0.000531510757612
ko05169	Epstein-Barr virus infection	8/757	206/7206	0.000733121990487
ko04745	Phototransduction - fly	11/757	38/7206	0.00134162496984
ko05162	Measles	3/757	120/7206	0.00144644742887
ko04740	Olfactory transduction	18/757	80/7206	0.00144724049104
ko04070	Phosphatidylinositol signaling system	23/757	112/7206	0.00153083792782
ko04120	Ubiquitin mediated proteolysis	4/757	138/7206	0.00172040111806
ko04630	Jak-STAT signaling pathway	4/757	132/7206	0.00231793841685
ko03008	Ribosome biogenesis in eukaryotes	1/757	79/7206	0.00266355904043
ko04930	Type II diabetes mellitus	13/757	54/7206	0.00319378545626
ko04621	NOD-like receptor signaling pathway	6/757	157/7206	0.00345883331228
ko04915	Estrogen signaling pathway	25/757	131/7206	0.003476473419
ko04924	Renin secretion	18/757	86/7206	0.00384979884205
ko00240	Pyrimidine metabolism	3/757	110/7206	0.00420287878366
ko05410	Hypertrophic cardiomyopathy (HCM)	20/757	100/7206	0.00444425312711
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/757	182/7206	0.00449550294879
ko04964	Proximal tubule bicarbonate reclamation	8/757	29/7206	0.00824759747018
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/757	59/7206	0.00853060723538
ko04540	Gap junction	23/757	128/7206	0.00855312158317
ko04110	Cell cycle	6/757	145/7206	0.00871379314705
ko04750	Inflammatory mediator regulation of TRP channels	22/757	122/7206	0.0105370571785
ko05205	Proteoglycans in cancer	16/757	271/7206	0.0111296883678
ko05012	Parkinson's disease	7/757	155/7206	0.0112345217159
ko04640	Hematopoietic cell lineage	1/757	64/7206	0.0125456304873
ko00330	Arginine and proline metabolism	1/757	61/7206	0.0186811685697
ko04141	Protein processing in endoplasmic reticulum	10/757	184/7206	0.0202238855064
ko05140	Leishmaniasis	2/757	75/7206	0.0215201536634
ko04612	Antigen processing and presentation	2/757	77/7206	0.0224310556172
ko04146	Peroxisome	3/757	89/7206	0.0226715658145
ko04071	Sphingolipid signaling pathway	26/757	162/7206	0.0266861801664
ko00480	Glutathione metabolism	1/757	55/7206	0.026721110156
ko05321	Inflammatory bowel disease (IBD)	1/757	56/7206	0.0268243254404
ko00512	Mucin type O-glycan biosynthesis	7/757	29/7206	0.0272827788316
ko04014	Ras signaling pathway	41/757	279/7206	0.0277568945249
ko03018	RNA degradation	3/757	84/7206	0.0314444966312
ko05231	Choline metabolism in cancer	22/757	134/7206	0.0318240467159
ko05145	Toxoplasmosis	6/757	126/7206	0.0383333871058
ko00280	Valine, leucine and isoleucine degradation	1/757	54/7206	0.0406626456184
ko05215	Prostate cancer	5/757	111/7206	0.0406825189646
ko00515	Mannose type O-glycan biosynthesis	6/757	25/7206	0.040904837277
ko04064	NF-kappa B signaling pathway	4/757	96/7206	0.042602071869
ko05161	Hepatitis B	10/757	173/7206	0.0434627350626
ko05131	Shigellosis	3/757	82/7206	0.0440580797482
ko04137	Mitophagy - animal	3/757	82/7206	0.0440580797482
ko03320	PPAR signaling pathway	2/757	69/7206	0.0448560873332
ko04371	Apelin signaling pathway	27/757	177/7206	0.0459597346624
ko04966	Collecting duct acid secretion	6/757	26/7206	0.04862964653
ko04918	Thyroid hormone synthesis	15/757	86/7206	0.0487836187858