ko pathway ratio_in_study ratio_in_pop p_value ko04110 Cell cycle 39/369 145/7206 1.64054365133e-18 ko03040 Spliceosome 38/369 145/7206 1.22290928377e-17 ko04111 Cell cycle - yeast 28/369 90/7206 2.24112199185e-15 ko03030 DNA replication 16/369 38/7206 1.28417310583e-11 ko03440 Homologous recombination 16/369 41/7206 5.16515242542e-11 ko03013 RNA transport 31/369 166/7206 2.04192263264e-10 ko04113 Meiosis - yeast 19/369 70/7206 1.0874276313e-09 ko04080 Neuroactive ligand-receptor interaction 1/369 423/7206 4.54693305405e-09 ko03410 Base excision repair 12/369 38/7206 2.19653501691e-07 ko03008 Ribosome biogenesis in eukaryotes 17/369 79/7206 3.41634210824e-07 ko03430 Mismatch repair 9/369 22/7206 6.03528307132e-07 ko00240 Pyrimidine metabolism 19/369 110/7206 2.4916708852e-06 ko03460 Fanconi anemia pathway 12/369 51/7206 7.02751889061e-06 ko03420 Nucleotide excision repair 10/369 46/7206 8.53420210849e-05 ko05166 HTLV-I infection 31/369 292/7206 0.000103820662787 ko04020 Calcium signaling pathway 2/369 265/7206 0.000165285213725 ko04218 Cellular senescence 21/369 177/7206 0.000338791339502 ko04114 Oocyte meiosis 17/369 139/7206 0.000694879601916 ko04914 Progesterone-mediated oocyte maturation 14/369 104/7206 0.000786211507529 ko03018 RNA degradation 12/369 84/7206 0.00108476411475 ko00230 Purine metabolism 21/369 194/7206 0.00126801762962 ko05010 Alzheimer's disease 2/369 202/7206 0.00305751538968 ko04152 AMPK signaling pathway 1/369 161/7206 0.0033064583329 ko04621 NOD-like receptor signaling pathway 1/369 157/7206 0.00497390196718 ko03450 Non-homologous end-joining 4/369 15/7206 0.00588471316028 ko04022 cGMP-PKG signaling pathway 3/369 216/7206 0.00700592298303 ko03015 mRNA surveillance pathway 11/369 93/7206 0.0076271127626 ko04910 Insulin signaling pathway 2/369 172/7206 0.0126773591093 ko04115 p53 signaling pathway 9/369 74/7206 0.0127409030018 ko04514 Cell adhesion molecules (CAMs) 1/369 130/7206 0.0147210724872 ko03020 RNA polymerase 5/369 29/7206 0.014722822105 ko00514 Other types of O-glycan biosynthesis 5/369 30/7206 0.0169460363889 ko00190 Oxidative phosphorylation 1/369 127/7206 0.0223152158462 ko05012 Parkinson's disease 2/369 155/7206 0.0249405188172 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/369 182/7206 0.0258133643205 ko04911 Insulin secretion 1/369 117/7206 0.0312813631788 ko04668 TNF signaling pathway 1/369 120/7206 0.0325947806833 ko04921 Oxytocin signaling pathway 4/369 209/7206 0.0360696358874 ko05203 Viral carcinogenesis 22/369 277/7206 0.0363488345068 ko01521 EGFR tyrosine kinase inhibitor resistance 1/369 106/7206 0.0441383002693 ko04012 ErbB signaling pathway 1/369 109/7206 0.0449528611433 ko05222 Small cell lung cancer 9/369 89/7206 0.0467034466421