ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	86/630	145/7206	8.31941208759e-55
ko05322	Systemic lupus erythematosus	65/630	151/7206	2.7338870605e-30
ko04110	Cell cycle	61/630	145/7206	8.62260781349e-28
ko04111	Cell cycle - yeast	43/630	90/7206	1.50992050949e-22
ko03030	DNA replication	28/630	38/7206	2.70578890691e-22
ko03013	RNA transport	57/630	166/7206	8.22233433333e-21
ko05034	Alcoholism	66/630	238/7206	2.61182685609e-18
ko03008	Ribosome biogenesis in eukaryotes	34/630	79/7206	2.58551829823e-16
ko04113	Meiosis - yeast	30/630	70/7206	1.76700011183e-14
ko05203	Viral carcinogenesis	63/630	277/7206	4.45114126113e-13
ko03460	Fanconi anemia pathway	24/630	51/7206	6.2251921065e-13
ko03430	Mismatch repair	15/630	22/7206	1.08646857594e-11
ko03440	Homologous recombination	20/630	41/7206	2.3647596784e-11
ko03015	mRNA surveillance pathway	30/630	93/7206	1.00558810809e-10
ko00240	Pyrimidine metabolism	33/630	110/7206	1.0328627548e-10
ko04144	Endocytosis	4/630	342/7206	1.54559865174e-09
ko03410	Base excision repair	17/630	38/7206	4.13267992972e-09
ko03420	Nucleotide excision repair	18/630	46/7206	1.91294976738e-08
ko04024	cAMP signaling pathway	3/630	279/7206	3.1552305679e-08
ko03018	RNA degradation	23/630	84/7206	4.62198814423e-07
ko04060	Cytokine-cytokine receptor interaction	1/630	191/7206	7.35248724942e-07
ko04921	Oxytocin signaling pathway	2/630	209/7206	1.38208576292e-06
ko04723	Retrograde endocannabinoid signaling	1/630	175/7206	3.89927933212e-06
ko04022	cGMP-PKG signaling pathway	3/630	216/7206	6.82333910132e-06
ko04725	Cholinergic synapse	1/630	160/7206	1.23068465267e-05
ko03020	RNA polymerase	11/630	29/7206	1.67141805828e-05
ko04270	Vascular smooth muscle contraction	1/630	154/7206	1.78939732475e-05
ko04621	NOD-like receptor signaling pathway	1/630	157/7206	1.9272026109e-05
ko04062	Chemokine signaling pathway	3/630	201/7206	2.06546373834e-05
ko04072	Phospholipase D signaling pathway	3/630	197/7206	3.00782081343e-05
ko04014	Ras signaling pathway	7/630	279/7206	3.07336806939e-05
ko04151	PI3K-Akt signaling pathway	14/630	390/7206	6.36362880488e-05
ko04530	Tight junction	5/630	228/7206	6.6414981246e-05
ko04261	Adrenergic signaling in cardiomyocytes	4/630	205/7206	7.91666717405e-05
ko04810	Regulation of actin cytoskeleton	7/630	264/7206	8.27966809102e-05
ko04713	Circadian entrainment	1/630	136/7206	8.71399868975e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/630	182/7206	8.99205075481e-05
ko04015	Rap1 signaling pathway	8/630	278/7206	0.000123205660187
ko04915	Estrogen signaling pathway	1/630	131/7206	0.000128760911116
ko04371	Apelin signaling pathway	3/630	177/7206	0.000129396126555
ko04114	Oocyte meiosis	26/630	139/7206	0.000184505739702
ko03010	Ribosome	1/630	129/7206	0.000199439070699
ko04360	Axon guidance	6/630	233/7206	0.000209516151179
ko03022	Basal transcription factors	12/630	44/7206	0.000276807726455
ko04728	Dopaminergic synapse	4/630	185/7206	0.000322682962001
ko04611	Platelet activation	3/630	163/7206	0.000381980366397
ko04510	Focal adhesion	7/630	240/7206	0.000419881643959
ko04010	MAPK signaling pathway	12/630	321/7206	0.000531141701702
ko05202	Transcriptional misregulation in cancer	31/630	188/7206	0.000541401217277
ko04070	Phosphatidylinositol signaling system	1/630	112/7206	0.000614942862076
ko04380	Osteoclast differentiation	2/630	134/7206	0.000925330513482
ko05231	Choline metabolism in cancer	2/630	134/7206	0.000925330513482
ko05032	Morphine addiction	1/630	110/7206	0.000927996630213
ko04972	Pancreatic secretion	1/630	111/7206	0.000953652390903
ko04670	Leukocyte transendothelial migration	3/630	151/7206	0.0011270896799
ko05145	Toxoplasmosis	2/630	126/7206	0.00128304722517
ko04540	Gap junction	2/630	128/7206	0.00129940466048
ko05166	HTLV-I infection	42/630	292/7206	0.00135967779019
ko05142	Chagas disease (American trypanosomiasis)	2/630	130/7206	0.00136038191283
ko04071	Sphingolipid signaling pathway	4/630	162/7206	0.00178128080513
ko00230	Purine metabolism	30/630	194/7206	0.00179689269493
ko04912	GnRH signaling pathway	2/630	122/7206	0.00185062492082
ko04750	Inflammatory mediator regulation of TRP channels	2/630	122/7206	0.00185062492082
ko04660	T cell receptor signaling pathway	2/630	124/7206	0.00189420445108
ko00564	Glycerophospholipid metabolism	1/630	99/7206	0.00196331567951
ko05146	Amoebiasis	1/630	99/7206	0.00196331567951
ko04620	Toll-like receptor signaling pathway	1/630	100/7206	0.00197971515873
ko04914	Progesterone-mediated oocyte maturation	19/630	104/7206	0.00225071990829
ko04722	Neurotrophin signaling pathway	4/630	160/7206	0.00255718654744
ko04911	Insulin secretion	2/630	117/7206	0.00266102510269
ko04668	TNF signaling pathway	2/630	120/7206	0.00276434391076
ko04933	AGE-RAGE signaling pathway in diabetic complications	3/630	135/7206	0.00315711275178
ko05160	Hepatitis C	4/630	153/7206	0.00347564164115
ko05152	Tuberculosis	6/630	187/7206	0.00368257322969
ko04146	Peroxisome	1/630	89/7206	0.00423299514223
ko00562	Inositol phosphate metabolism	1/630	89/7206	0.00423299514223
ko05120	Epithelial cell signaling in Helicobacter pylori infection	1/630	92/7206	0.00435992279766
ko04630	Jak-STAT signaling pathway	3/630	132/7206	0.00451358716744
ko04142	Lysosome	4/630	151/7206	0.0050004057995
ko04924	Renin secretion	1/630	86/7206	0.00623408322325
ko05133	Pertussis	1/630	87/7206	0.00632981379196
ko04145	Phagosome	5/630	162/7206	0.00690584490749
ko04520	Adherens junction	2/630	103/7206	0.00782684205743
ko04925	Aldosterone synthesis and secretion	2/630	105/7206	0.00796343590438
ko04659	Th17 cell differentiation	2/630	106/7206	0.00811872099995
ko04740	Olfactory transduction	1/630	80/7206	0.00906401005767
ko04138	Autophagy - yeast	1/630	81/7206	0.00908786338678
ko04910	Insulin signaling pathway	6/630	172/7206	0.00916245579373
ko04137	Mitophagy - animal	1/630	82/7206	0.00919310611728
ko05132	Salmonella infection	2/630	98/7206	0.0111589593167
ko04720	Long-term potentiation	2/630	99/7206	0.0111916706482
ko04141	Protein processing in endoplasmic reticulum	7/630	184/7206	0.0117861682387
ko04931	Insulin resistance	4/630	137/7206	0.0132499780654
ko05140	Leishmaniasis	1/630	75/7206	0.0132524213446
ko04370	VEGF signaling pathway	1/630	77/7206	0.0133526260369
ko04664	Fc epsilon RI signaling pathway	1/630	77/7206	0.0133526260369
ko04923	Regulation of lipolysis in adipocytes	1/630	77/7206	0.0133526260369
ko04120	Ubiquitin mediated proteolysis	21/630	138/7206	0.0135482893582
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	1/630	79/7206	0.0139147973211
ko04218	Cellular senescence	25/630	177/7206	0.0147551955171
ko05205	Proteoglycans in cancer	13/630	271/7206	0.0156984557794
ko05167	Kaposi's sarcoma-associated herpesvirus infection	8/630	191/7206	0.0192828884854
ko05030	Cocaine addiction	1/630	73/7206	0.0196457403389
ko05031	Amphetamine addiction	2/630	91/7206	0.0229218570805
ko04066	HIF-1 signaling pathway	4/630	123/7206	0.0238456364124
ko04012	ErbB signaling pathway	3/630	109/7206	0.0243560634708
ko04217	Necroptosis	24/630	178/7206	0.0305900351924
ko04115	p53 signaling pathway	12/630	74/7206	0.0348534091905
ko03450	Non-homologous end-joining	4/630	15/7206	0.0362455519671
ko05164	Influenza A	7/630	167/7206	0.0362573458331
ko04139	Mitophagy - yeast	7/630	37/7206	0.0385658549238
ko04622	RIG-I-like receptor signaling pathway	1/630	62/7206	0.0407916094731
ko00330	Arginine and proline metabolism	1/630	61/7206	0.0408022791252
ko05110	Vibrio cholerae infection	1/630	63/7206	0.0410893165557
ko04512	ECM-receptor interaction	2/630	79/7206	0.0447955556086
ko05230	Central carbon metabolism in cancer	2/630	81/7206	0.0453049660983
ko05211	Renal cell carcinoma	3/630	96/7206	0.0453417135797
ko04658	Th1 and Th2 cell differentiation	3/630	96/7206	0.0453417135797
ko04064	NF-kappa B signaling pathway	3/630	96/7206	0.0453417135797
ko04152	AMPK signaling pathway	7/630	161/7206	0.0470862070921