ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	117/861	423/7206	1.13084044997e-19
ko04020	Calcium signaling pathway	76/861	265/7206	5.33034519106e-14
ko04713	Circadian entrainment	45/861	136/7206	5.00588607179e-11
ko04724	Glutamatergic synapse	48/861	152/7206	7.26747831095e-11
ko05032	Morphine addiction	37/861	110/7206	1.60075140919e-09
ko04921	Oxytocin signaling pathway	56/861	209/7206	2.99736679171e-09
ko04024	cAMP signaling pathway	68/861	279/7206	4.21463224658e-09
ko04725	Cholinergic synapse	46/861	160/7206	6.67434055721e-09
ko04022	cGMP-PKG signaling pathway	54/861	216/7206	8.55272095684e-08
ko04911	Insulin secretion	35/861	117/7206	1.29604218649e-07
ko04070	Phosphatidylinositol signaling system	34/861	112/7206	1.32150251822e-07
ko05033	Nicotine addiction	22/861	56/7206	1.52461181695e-07
ko03040	Spliceosome	1/861	145/7206	3.59728762214e-07
ko04710	Circadian rhythm	18/861	43/7206	6.80095440244e-07
ko04728	Dopaminergic synapse	46/861	185/7206	7.93166622481e-07
ko04727	GABAergic synapse	32/861	110/7206	8.97057983179e-07
ko04721	Synaptic vesicle cycle	26/861	80/7206	9.33392596792e-07
ko03010	Ribosome	1/861	129/7206	2.90553188412e-06
ko05322	Systemic lupus erythematosus	3/861	151/7206	1.09005439409e-05
ko03013	RNA transport	4/861	166/7206	1.51330972652e-05
ko04970	Salivary secretion	27/861	95/7206	1.54405115763e-05
ko04072	Phospholipase D signaling pathway	45/861	197/7206	1.63242172243e-05
ko05031	Amphetamine addiction	26/861	91/7206	2.21263861549e-05
ko04925	Aldosterone synthesis and secretion	28/861	105/7206	2.75835350372e-05
ko04723	Retrograde endocannabinoid signaling	40/861	175/7206	4.39070439418e-05
ko04360	Axon guidance	49/861	233/7206	5.36226624108e-05
ko04971	Gastric acid secretion	26/861	98/7206	5.89578770339e-05
ko04726	Serotonergic synapse	33/861	137/7206	7.94053872322e-05
ko04014	Ras signaling pathway	55/861	279/7206	0.000144635564199
ko04514	Cell adhesion molecules (CAMs)	31/861	130/7206	0.000165329534171
ko04922	Glucagon signaling pathway	30/861	128/7206	0.000261473977721
ko04010	MAPK signaling pathway	60/861	321/7206	0.000388739128553
ko04924	Renin secretion	22/861	86/7206	0.000569195220206
ko04972	Pancreatic secretion	26/861	111/7206	0.000575704216383
ko04750	Inflammatory mediator regulation of TRP channels	28/861	122/7206	0.000577835368665
ko04720	Long-term potentiation	24/861	99/7206	0.000795798032099
ko04261	Adrenergic signaling in cardiomyocytes	41/861	205/7206	0.00092564597852
ko04371	Apelin signaling pathway	36/861	177/7206	0.00134927260401
ko04270	Vascular smooth muscle contraction	32/861	154/7206	0.00150443985702
ko04730	Long-term depression	19/861	78/7206	0.00220361883651
ko04711	Circadian rhythm - fly	6/861	13/7206	0.00233214307044
ko00562	Inositol phosphate metabolism	21/861	89/7206	0.00247533836876
ko05203	Viral carcinogenesis	18/861	277/7206	0.00324155313566
ko04745	Phototransduction - fly	11/861	38/7206	0.0037844597746
ko05016	Huntington's disease	13/861	215/7206	0.00522565929249
ko04110	Cell cycle	7/861	145/7206	0.00604567016454
ko05231	Choline metabolism in cancer	27/861	134/7206	0.00651075243033
ko04015	Rap1 signaling pathway	48/861	278/7206	0.00798892511849
ko04919	Thyroid hormone signaling pathway	28/861	143/7206	0.00849622922232
ko05110	Vibrio cholerae infection	15/861	63/7206	0.00926384731998
ko04120	Ubiquitin mediated proteolysis	7/861	138/7206	0.0109786034369
ko00520	Amino sugar and nucleotide sugar metabolism	1/861	55/7206	0.0118464774274
ko05030	Cocaine addiction	16/861	73/7206	0.0162969646625
ko03050	Proteasome	1/861	54/7206	0.0179880676241
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/861	14/7206	0.0191116442188
ko04923	Regulation of lipolysis in adipocytes	16/861	77/7206	0.0215956751751
ko05230	Central carbon metabolism in cancer	17/861	81/7206	0.0229525818043
ko04666	Fc gamma R-mediated phagocytosis	23/861	122/7206	0.0235775091823
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/861	59/7206	0.0246910078926
ko04966	Collecting duct acid secretion	7/861	26/7206	0.0289935537133
ko04141	Protein processing in endoplasmic reticulum	13/861	184/7206	0.0378066748246
ko04540	Gap junction	23/861	128/7206	0.0391057869471
ko05219	Bladder cancer	1/861	48/7206	0.0399230092325
ko04113	Meiosis - yeast	3/861	70/7206	0.0420333053082
ko04066	HIF-1 signaling pathway	22/861	123/7206	0.0486796848099