ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	34/587	56/7206	1.47667749163e-23
ko04724	Glutamatergic synapse	55/587	152/7206	7.48705185006e-23
ko04080	Neuroactive ligand-receptor interaction	97/587	423/7206	2.20391383917e-22
ko05032	Morphine addiction	43/587	110/7206	1.40313692681e-19
ko04727	GABAergic synapse	40/587	110/7206	5.56527190775e-17
ko04723	Retrograde endocannabinoid signaling	48/587	175/7206	1.44489735616e-14
ko04728	Dopaminergic synapse	49/587	185/7206	3.37613984251e-14
ko04713	Circadian entrainment	38/587	136/7206	4.82905536741e-12
ko04024	cAMP signaling pathway	56/587	279/7206	1.37686085579e-10
ko04725	Cholinergic synapse	39/587	160/7206	2.37698676607e-10
ko04721	Synaptic vesicle cycle	25/587	80/7206	1.8128003961e-09
ko05030	Cocaine addiction	23/587	73/7206	6.8306014448e-09
ko04911	Insulin secretion	30/587	117/7206	8.38351810042e-09
ko05031	Amphetamine addiction	25/587	91/7206	3.38034304021e-08
ko04514	Cell adhesion molecules (CAMs)	30/587	130/7206	1.1149539892e-07
ko04261	Adrenergic signaling in cardiomyocytes	40/587	205/7206	1.47312798865e-07
ko04010	MAPK signaling pathway	54/587	321/7206	1.80158250698e-07
ko04921	Oxytocin signaling pathway	40/587	209/7206	2.32371528072e-07
ko04020	Calcium signaling pathway	47/587	265/7206	2.40314289581e-07
ko04072	Phospholipase D signaling pathway	38/587	197/7206	4.00109369536e-07
ko05203	Viral carcinogenesis	4/587	277/7206	1.54761425938e-06
ko04720	Long-term potentiation	23/587	99/7206	3.02662881575e-06
ko04742	Taste transduction	17/587	61/7206	4.36727012341e-06
ko04925	Aldosterone synthesis and secretion	22/587	105/7206	2.8598805866e-05
ko04360	Axon guidance	37/587	233/7206	7.29465229755e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/587	79/7206	0.00016244871822
ko05414	Dilated cardiomyopathy	21/587	112/7206	0.000299095932165
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/587	14/7206	0.000484502172304
ko04060	Cytokine-cytokine receptor interaction	4/587	191/7206	0.000669854473293
ko03013	RNA transport	3/587	166/7206	0.00080556638356
ko04915	Estrogen signaling pathway	22/587	131/7206	0.000985281017279
ko05168	Herpes simplex infection	4/587	182/7206	0.00134446649371
ko04970	Salivary secretion	17/587	95/7206	0.00182453410309
ko04726	Serotonergic synapse	22/587	137/7206	0.0022015121518
ko05014	Amyotrophic lateral sclerosis (ALS)	14/587	74/7206	0.0022660620474
ko00515	Mannose type O-glycan biosynthesis	7/587	25/7206	0.00301011848393
ko04972	Pancreatic secretion	18/587	111/7206	0.00432199437741
ko05205	Proteoglycans in cancer	10/587	271/7206	0.00436074209921
ko04621	NOD-like receptor signaling pathway	4/587	157/7206	0.0070780443206
ko00512	Mucin type O-glycan biosynthesis	7/587	29/7206	0.00734940232135
ko04022	cGMP-PKG signaling pathway	29/587	216/7206	0.00740031146755
ko00240	Pyrimidine metabolism	2/587	110/7206	0.00799328296759
ko05410	Hypertrophic cardiomyopathy (HCM)	16/587	100/7206	0.00847079047077
ko05169	Epstein-Barr virus infection	7/587	206/7206	0.00910631917414
ko05164	Influenza A	5/587	167/7206	0.00950230295578
ko04923	Regulation of lipolysis in adipocytes	13/587	77/7206	0.0100990171861
ko04930	Type II diabetes mellitus	10/587	54/7206	0.0107721543001
ko04730	Long-term depression	13/587	78/7206	0.0109742940222
ko04141	Protein processing in endoplasmic reticulum	6/587	184/7206	0.0129806694181
ko04110	Cell cycle	4/587	145/7206	0.0130975432355
ko03018	RNA degradation	1/587	84/7206	0.0139261267653
ko04260	Cardiac muscle contraction	15/587	98/7206	0.0146592141812
ko00513	Various types of N-glycan biosynthesis	8/587	42/7206	0.0183422627922
ko04144	Endocytosis	40/587	342/7206	0.0192674889089
ko04612	Antigen processing and presentation	1/587	77/7206	0.01969637745
ko03008	Ribosome biogenesis in eukaryotes	1/587	79/7206	0.0202390218337
ko04670	Leukocyte transendothelial migration	5/587	151/7206	0.0235322952906
ko05322	Systemic lupus erythematosus	5/587	151/7206	0.0235322952906
ko04962	Vasopressin-regulated water reabsorption	10/587	58/7206	0.0246279148897
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/587	182/7206	0.0277070889096
ko04214	Apoptosis - fly	1/587	72/7206	0.0286081976749
ko00190	Oxidative phosphorylation	4/587	127/7206	0.0329178498781
ko05231	Choline metabolism in cancer	18/587	134/7206	0.0359733621872
ko04740	Olfactory transduction	12/587	80/7206	0.0363527687636
ko04971	Gastric acid secretion	14/587	98/7206	0.0377850352563