ko pathway ratio_in_study ratio_in_pop p_value ko00350 Tyrosine metabolism 14/369 33/7206 2.2492463909e-10 ko04974 Protein digestion and absorption 21/369 96/7206 1.01662241492e-08 ko04976 Bile secretion 19/369 80/7206 1.2365871122e-08 ko00380 Tryptophan metabolism 14/369 50/7206 1.15815908844e-07 ko04610 Complement and coagulation cascades 17/369 79/7206 3.41634210824e-07 ko00360 Phenylalanine metabolism 8/369 17/7206 7.0964379329e-07 ko05200 Pathways in cancer 5/369 492/7206 7.11123208759e-07 ko04975 Fat digestion and absorption 11/369 35/7206 7.51078060428e-07 ko00950 Isoquinoline alkaloid biosynthesis 6/369 10/7206 3.05301907972e-06 ko00983 Drug metabolism - other enzymes 11/369 42/7206 5.56966891661e-06 ko00643 Styrene degradation 4/369 4/7206 6.77026974773e-06 ko04978 Mineral absorption 10/369 40/7206 2.33764301098e-05 ko00830 Retinol metabolism 10/369 42/7206 3.70152534393e-05 ko03320 PPAR signaling pathway 13/369 69/7206 3.80968611519e-05 ko00982 Drug metabolism - cytochrome P450 9/369 37/7206 7.60530311557e-05 ko04360 Axon guidance 1/369 233/7206 0.000107126683927 ko05204 Chemical carcinogenesis 10/369 48/7206 0.000124936973711 ko00140 Steroid hormone biosynthesis 9/369 41/7206 0.000178541181137 ko04614 Renin-angiotensin system 6/369 18/7206 0.000189976891025 ko00120 Primary bile acid biosynthesis 6/369 20/7206 0.000363470294106 ko04015 Rap1 signaling pathway 3/369 278/7206 0.000441482846277 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 3/369 4/7206 0.000512653704346 ko00260 Glycine, serine and threonine metabolism 9/369 48/7206 0.000622109100509 ko00591 Linoleic acid metabolism 6/369 22/7206 0.00064125226846 ko04977 Vitamin digestion and absorption 6/369 22/7206 0.00064125226846 ko02010 ABC transporters 8/369 39/7206 0.000665279302143 ko04010 MAPK signaling pathway 5/369 321/7206 0.00111192391212 ko00590 Arachidonic acid metabolism 9/369 52/7206 0.00113880857949 ko00232 Caffeine metabolism 3/369 5/7206 0.00123291595627 ko00340 Histidine metabolism 6/369 25/7206 0.00133588028334 ko04972 Pancreatic secretion 14/369 111/7206 0.00150166239031 ko00592 alpha-Linolenic acid metabolism 5/369 19/7206 0.00219453911485 ko04740 Olfactory transduction 11/369 80/7206 0.00237054172117 ko00362 Benzoate degradation 3/369 6/7206 0.00237233929839 ko05224 Breast cancer 1/369 174/7206 0.002403116991 ko00250 Alanine, aspartate and glutamate metabolism 7/369 38/7206 0.00277486188451 ko03013 RNA transport 1/369 166/7206 0.00348640425832 ko00100 Steroid biosynthesis 5/369 21/7206 0.00352919445923 ko00980 Metabolism of xenobiotics by cytochrome P450 7/369 40/7206 0.00375416161705 ko04146 Peroxisome 11/369 89/7206 0.00548052754508 ko04150 mTOR signaling pathway 2/369 184/7206 0.00614890678637 ko04151 PI3K-Akt signaling pathway 9/369 390/7206 0.00637220768434 ko00640 Propanoate metabolism 6/369 34/7206 0.00687550143188 ko05016 Huntington's disease 3/369 215/7206 0.00697599313598 ko03040 Spliceosome 1/369 145/7206 0.00699189716146 ko00071 Fatty acid degradation 7/369 45/7206 0.00733949925076 ko05203 Viral carcinogenesis 5/369 277/7206 0.00758158683972 ko04218 Cellular senescence 2/369 177/7206 0.00875645523169 ko00270 Cysteine and methionine metabolism 7/369 47/7206 0.00932067087704 ko04120 Ubiquitin mediated proteolysis 1/369 138/7206 0.0101697703894 ko04114 Oocyte meiosis 1/369 139/7206 0.0102255385944 ko05205 Proteoglycans in cancer 5/369 271/7206 0.010487248808 ko00330 Arginine and proline metabolism 8/369 61/7206 0.0119619816001 ko00920 Sulfur metabolism 3/369 10/7206 0.012207572758 ko00965 Betalain biosynthesis 2/369 4/7206 0.0146470644355 ko04933 AGE-RAGE signaling pathway in diabetic complications 1/369 135/7206 0.0154974251712 ko04144 Endocytosis 8/369 342/7206 0.0159928107378 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 3/369 11/7206 0.0161573963374 ko04722 Neurotrophin signaling pathway 2/369 160/7206 0.0174544288859 ko04014 Ras signaling pathway 6/369 279/7206 0.0178049235817 ko04973 Carbohydrate digestion and absorption 6/369 42/7206 0.0190406888431 ko04066 HIF-1 signaling pathway 1/369 123/7206 0.0213652023863 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/369 5/7206 0.0235898300885 ko00053 Ascorbate and aldarate metabolism 4/369 22/7206 0.0237763350489 ko00052 Galactose metabolism 5/369 33/7206 0.0249145019094 ko04621 NOD-like receptor signaling pathway 2/369 157/7206 0.0254425242076 ko00620 Pyruvate metabolism 6/369 46/7206 0.0286834021233 ko00410 beta-Alanine metabolism 5/369 35/7206 0.0313706394918 ko05162 Measles 1/369 120/7206 0.0325947806833 ko04919 Thyroid hormone signaling pathway 2/369 143/7206 0.0344417047742 ko05010 Alzheimer's disease 4/369 202/7206 0.0348354861437 ko04744 Phototransduction 5/369 36/7206 0.0349565858084 ko05169 Epstein-Barr virus infection 4/369 206/7206 0.0352463798012 ko05161 Hepatitis B 3/369 173/7206 0.0354496220287 ko00561 Glycerolipid metabolism 7/369 63/7206 0.0410078828137 ko00040 Pentose and glucuronate interconversions 4/369 26/7206 0.0414242937281 ko04659 Th17 cell differentiation 1/369 106/7206 0.0441383002693 ko04072 Phospholipase D signaling pathway 4/369 197/7206 0.0473203513559