ko pathway ratio_in_study ratio_in_pop p_value ko04110 Cell cycle 27/210 145/7206 5.24663998704e-15 ko04111 Cell cycle - yeast 20/210 90/7206 6.70550883516e-13 ko04113 Meiosis - yeast 14/210 70/7206 9.45984882355e-09 ko03410 Base excision repair 10/210 38/7206 8.26604982745e-08 ko03030 DNA replication 10/210 38/7206 8.26604982745e-08 ko05322 Systemic lupus erythematosus 16/210 151/7206 7.23888801345e-06 ko03008 Ribosome biogenesis in eukaryotes 11/210 79/7206 1.57348869393e-05 ko03040 Spliceosome 15/210 145/7206 1.88500140339e-05 ko05202 Transcriptional misregulation in cancer 17/210 188/7206 3.08237374077e-05 ko05206 MicroRNAs in cancer 16/210 177/7206 5.32866239476e-05 ko05034 Alcoholism 18/210 238/7206 0.000186393592046 ko04114 Oocyte meiosis 13/210 139/7206 0.000192850584453 ko00240 Pyrimidine metabolism 11/210 110/7206 0.000336832636337 ko04144 Endocytosis 1/210 342/7206 0.000746319699951 ko05166 HTLV-I infection 19/210 292/7206 0.000974745101581 ko04218 Cellular senescence 13/210 177/7206 0.00191768050281 ko04330 Notch signaling pathway 7/210 62/7206 0.00203818340567 ko05203 Viral carcinogenesis 17/210 277/7206 0.00312054629755 ko05217 Basal cell carcinoma 7/210 68/7206 0.00346871688283 ko05224 Breast cancer 12/210 174/7206 0.00474080820327 ko03440 Homologous recombination 5/210 41/7206 0.00639519158792 ko04550 Signaling pathways regulating pluripotency of stem cells 11/210 165/7206 0.00863169930451 ko03420 Nucleotide excision repair 5/210 46/7206 0.0104055786923 ko03460 Fanconi anemia pathway 5/210 51/7206 0.0158694366637 ko04115 p53 signaling pathway 6/210 74/7206 0.0204090628008 ko04390 Hippo signaling pathway 11/210 188/7206 0.0248073072514 ko03430 Mismatch repair 3/210 22/7206 0.0249773952669 ko03013 RNA transport 10/210 166/7206 0.0299040713505 ko05220 Chronic myeloid leukemia 6/210 85/7206 0.0371396329795 ko05152 Tuberculosis 1/210 187/7206 0.0454133952337 ko04060 Cytokine-cytokine receptor interaction 1/210 191/7206 0.046034209192 ko00270 Cysteine and methionine metabolism 4/210 47/7206 0.0471638223863