ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	98/787	145/7206	5.67554256068e-61
ko04110	Cell cycle	62/787	145/7206	2.61340392566e-23
ko03030	DNA replication	28/787	38/7206	1.23178083625e-19
ko04080	Neuroactive ligand-receptor interaction	2/787	423/7206	3.57234214303e-19
ko04111	Cell cycle - yeast	42/787	90/7206	7.40821733595e-18
ko03410	Base excision repair	26/787	38/7206	5.07209238867e-17
ko03013	RNA transport	55/787	166/7206	6.67489825374e-15
ko03008	Ribosome biogenesis in eukaryotes	35/787	79/7206	3.15213724317e-14
ko04113	Meiosis - yeast	30/787	70/7206	6.36587658411e-12
ko03015	mRNA surveillance pathway	35/787	93/7206	1.02028346249e-11
ko00240	Pyrimidine metabolism	38/787	110/7206	2.71926014482e-11
ko03430	Mismatch repair	15/787	22/7206	2.70340553949e-10
ko04020	Calcium signaling pathway	3/787	265/7206	3.09232891767e-10
ko05322	Systemic lupus erythematosus	44/787	151/7206	4.39346338794e-10
ko03460	Fanconi anemia pathway	23/787	51/7206	5.53282644788e-10
ko03440	Homologous recombination	20/787	41/7206	1.33384091993e-09
ko03420	Nucleotide excision repair	21/787	46/7206	2.38651398633e-09
ko04144	Endocytosis	9/787	342/7206	7.55936970006e-09
ko03018	RNA degradation	28/787	84/7206	2.82256801787e-08
ko04723	Retrograde endocannabinoid signaling	1/787	175/7206	4.99098447734e-08
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/787	182/7206	3.66949209697e-07
ko05012	Parkinson's disease	1/787	155/7206	6.20545145691e-07
ko04921	Oxytocin signaling pathway	4/787	209/7206	8.1863753774e-07
ko04060	Cytokine-cytokine receptor interaction	3/787	191/7206	8.27592446022e-07
ko04726	Serotonergic synapse	1/787	137/7206	4.78225449436e-06
ko04270	Vascular smooth muscle contraction	2/787	154/7206	5.41326401658e-06
ko05217	Basal cell carcinoma	21/787	68/7206	6.16517507606e-06
ko04024	cAMP signaling pathway	10/787	279/7206	8.56773415432e-06
ko04022	cGMP-PKG signaling pathway	6/787	216/7206	1.15880744047e-05
ko04072	Phospholipase D signaling pathway	5/787	197/7206	1.38796269726e-05
ko05034	Alcoholism	48/787	238/7206	1.88406695444e-05
ko04530	Tight junction	7/787	228/7206	1.91126973884e-05
ko04550	Signaling pathways regulating pluripotency of stem cells	37/787	165/7206	1.97480959821e-05
ko04371	Apelin signaling pathway	4/787	177/7206	2.34352645973e-05
ko03020	RNA polymerase	12/787	29/7206	2.35695173264e-05
ko04621	NOD-like receptor signaling pathway	3/787	157/7206	2.53291117721e-05
ko04151	PI3K-Akt signaling pathway	19/787	390/7206	2.5529399964e-05
ko04725	Cholinergic synapse	3/787	160/7206	2.69308843309e-05
ko04014	Ras signaling pathway	11/787	279/7206	3.21505760996e-05
ko03022	Basal transcription factors	15/787	44/7206	3.58863420598e-05
ko04062	Chemokine signaling pathway	6/787	201/7206	4.66112473508e-05
ko04727	GABAergic synapse	1/787	110/7206	7.54297649297e-05
ko05032	Morphine addiction	1/787	110/7206	7.54297649297e-05
ko03010	Ribosome	2/787	129/7206	8.27517074612e-05
ko05142	Chagas disease (American trypanosomiasis)	2/787	130/7206	8.54668634528e-05
ko04514	Cell adhesion molecules (CAMs)	2/787	130/7206	8.54668634528e-05
ko04611	Platelet activation	4/787	163/7206	0.000102392573556
ko04261	Adrenergic signaling in cardiomyocytes	7/787	205/7206	0.000143354301074
ko04912	GnRH signaling pathway	2/787	122/7206	0.00017964238988
ko05160	Hepatitis C	4/787	153/7206	0.000199388720392
ko04010	MAPK signaling pathway	16/787	321/7206	0.000222203500671
ko04380	Osteoclast differentiation	3/787	134/7206	0.000233797083875
ko04713	Circadian entrainment	3/787	136/7206	0.00023659224643
ko04971	Gastric acid secretion	1/787	98/7206	0.000245348914083
ko05146	Amoebiasis	1/787	99/7206	0.000249114486903
ko04620	Toll-like receptor signaling pathway	1/787	100/7206	0.00025742122495
ko04141	Protein processing in endoplasmic reticulum	6/787	184/7206	0.000265082788546
ko04670	Leukocyte transendothelial migration	4/787	151/7206	0.000291397580961
ko04915	Estrogen signaling pathway	3/787	131/7206	0.000336044839306
ko05166	HTLV-I infection	52/787	292/7206	0.000348702337787
ko05203	Viral carcinogenesis	50/787	277/7206	0.000356255316023
ko04970	Salivary secretion	1/787	95/7206	0.000367776603649
ko05414	Dilated cardiomyopathy	2/787	112/7206	0.00037263458961
ko04071	Sphingolipid signaling pathway	5/787	162/7206	0.000473793834517
ko04972	Pancreatic secretion	2/787	111/7206	0.000561295271204
ko04510	Focal adhesion	11/787	240/7206	0.000677089024549
ko05168	Herpes simplex infection	35/787	182/7206	0.00068572056702
ko04728	Dopaminergic synapse	7/787	185/7206	0.000715520107393
ko05145	Toxoplasmosis	3/787	126/7206	0.000726043431054
ko04330	Notch signaling pathway	16/787	62/7206	0.000761153017319
ko04015	Rap1 signaling pathway	14/787	278/7206	0.000773775479838
ko05202	Transcriptional misregulation in cancer	36/787	188/7206	0.000776925283348
ko05133	Pertussis	1/787	87/7206	0.000804002588044
ko04662	B cell receptor signaling pathway	1/787	88/7206	0.000816346792397
ko04920	Adipocytokine signaling pathway	1/787	89/7206	0.000842782719268
ko04668	TNF signaling pathway	3/787	120/7206	0.000993034344266
ko04933	AGE-RAGE signaling pathway in diabetic complications	4/787	135/7206	0.00115412379505
ko04120	Ubiquitin mediated proteolysis	28/787	138/7206	0.00126342720362
ko04114	Oocyte meiosis	28/787	139/7206	0.0013265068173
ko04911	Insulin secretion	3/787	117/7206	0.00143131697048
ko00564	Glycerophospholipid metabolism	2/787	99/7206	0.00168603333894
ko05410	Hypertrophic cardiomyopathy (HCM)	2/787	100/7206	0.00173038523828
ko05152	Tuberculosis	8/787	187/7206	0.00181179343431
ko04722	Neurotrophin signaling pathway	6/787	160/7206	0.00183828007159
ko04070	Phosphatidylinositol signaling system	3/787	112/7206	0.00201772712522
ko01200	Carbon metabolism	4/787	128/7206	0.00230948394854
ko00230	Purine metabolism	35/787	194/7206	0.00231497799154
ko05140	Leishmaniasis	1/787	75/7206	0.00260980869958
ko04923	Regulation of lipolysis in adipocytes	1/787	77/7206	0.00265133267397
ko04730	Long-term depression	1/787	78/7206	0.00273547250949
ko04950	Maturity onset diabetes of the young	9/787	29/7206	0.00280521149824
ko04750	Inflammatory mediator regulation of TRP channels	4/787	122/7206	0.00316476028352
ko04310	Wnt signaling pathway	33/787	181/7206	0.00341285778203
ko05134	Legionellosis	1/787	74/7206	0.00399306639616
ko04925	Aldosterone synthesis and secretion	3/787	105/7206	0.00408255369179
ko04659	Th17 cell differentiation	3/787	106/7206	0.00414035925958
ko04340	Hedgehog signaling pathway	14/787	58/7206	0.00434055505277
ko05231	Choline metabolism in cancer	5/787	134/7206	0.00466106123115
ko04924	Renin secretion	2/787	86/7206	0.00501203181024
ko03320	PPAR signaling pathway	1/787	69/7206	0.00570900539169
ko04540	Gap junction	5/787	128/7206	0.0063116536433
ko04650	Natural killer cell mediated cytotoxicity	3/787	97/7206	0.00812565509608
ko05132	Salmonella infection	3/787	98/7206	0.00820640502085
ko04640	Hematopoietic cell lineage	1/787	64/7206	0.00835902288955
ko04810	Regulation of actin cytoskeleton	16/787	264/7206	0.00860174373418
ko04740	Olfactory transduction	2/787	80/7206	0.0104477704378
ko00330	Arginine and proline metabolism	1/787	61/7206	0.0122919949039
ko04742	Taste transduction	1/787	61/7206	0.0122919949039
ko00561	Glycerolipid metabolism	1/787	63/7206	0.012778524782
ko00310	Lysine degradation	15/787	73/7206	0.0132325822473
ko04139	Mitophagy - yeast	9/787	37/7206	0.015741516975
ko04146	Peroxisome	3/787	89/7206	0.0159993733107
ko00562	Inositol phosphate metabolism	3/787	89/7206	0.0159993733107
ko05120	Epithelial cell signaling in Helicobacter pylori infection	3/787	92/7206	0.0167553232811
ko01212	Fatty acid metabolism	1/787	60/7206	0.0192371963758
ko05030	Cocaine addiction	2/787	73/7206	0.0215444124116
ko04910	Insulin signaling pathway	10/787	172/7206	0.0258567434481
ko04931	Insulin resistance	7/787	137/7206	0.0260027521295
ko04930	Type II diabetes mellitus	1/787	54/7206	0.0265359377859
ko00280	Valine, leucine and isoleucine degradation	1/787	54/7206	0.0265359377859
ko00520	Amino sugar and nucleotide sugar metabolism	1/787	55/7206	0.0270201410781
ko04660	T cell receptor signaling pathway	6/787	124/7206	0.0280939188321
ko04152	AMPK signaling pathway	9/787	161/7206	0.0287829195839
ko05230	Central carbon metabolism in cancer	3/787	81/7206	0.0310884853025
ko04137	Mitophagy - animal	3/787	82/7206	0.0312167225641
ko04390	Hippo signaling pathway	30/787	188/7206	0.032108959424
ko04712	Circadian rhythm - plant	3/787	7/7206	0.0324237445602
ko05167	Kaposi's sarcoma-associated herpesvirus infection	12/787	191/7206	0.0342614417666
ko05162	Measles	6/787	120/7206	0.0373496860668
ko04350	TGF-beta signaling pathway	18/787	103/7206	0.0381281800212
ko00510	N-Glycan biosynthesis	1/787	50/7206	0.0386924802371
ko05031	Amphetamine addiction	4/787	91/7206	0.0418466048536
ko04360	Axon guidance	16/787	233/7206	0.0423543653781
ko05110	Vibrio cholerae infection	2/787	63/7206	0.0425316046351
ko04370	VEGF signaling pathway	3/787	77/7206	0.0430831229307
ko04664	Fc epsilon RI signaling pathway	3/787	77/7206	0.0430831229307
ko04142	Lysosome	9/787	151/7206	0.0475561472069