ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 34/286 191/7206 6.94115725987e-14 ko05340 Primary immunodeficiency 13/286 30/7206 3.02539890387e-11 ko05164 Influenza A 26/286 167/7206 1.52726572278e-09 ko05162 Measles 20/286 120/7206 3.95448089854e-08 ko05330 Allograft rejection 9/286 24/7206 1.66797421836e-07 ko04650 Natural killer cell mediated cytotoxicity 17/286 97/7206 2.00473387196e-07 ko04621 NOD-like receptor signaling pathway 22/286 157/7206 2.0320178223e-07 ko04612 Antigen processing and presentation 15/286 77/7206 2.53504275997e-07 ko04659 Th17 cell differentiation 17/286 106/7206 7.49291753341e-07 ko05320 Autoimmune thyroid disease 9/286 29/7206 1.07196924459e-06 ko05140 Leishmaniasis 14/286 75/7206 1.10810627243e-06 ko05152 Tuberculosis 23/286 187/7206 1.15061186099e-06 ko05321 Inflammatory bowel disease (IBD) 12/286 56/7206 1.41588323182e-06 ko05168 Herpes simplex infection 22/286 182/7206 2.65860729847e-06 ko05332 Graft-versus-host disease 7/286 18/7206 3.1488524003e-06 ko04380 Osteoclast differentiation 18/286 134/7206 4.98413888778e-06 ko04145 Phagosome 20/286 162/7206 5.54546775329e-06 ko05145 Toxoplasmosis 17/286 126/7206 8.63802922391e-06 ko04620 Toll-like receptor signaling pathway 14/286 100/7206 3.57166950133e-05 ko04217 Necroptosis 19/286 178/7206 7.49959439418e-05 ko04672 Intestinal immune network for IgA production 8/286 37/7206 7.88933448917e-05 ko04658 Th1 and Th2 cell differentiation 13/286 96/7206 9.64986680409e-05 ko04062 Chemokine signaling pathway 20/286 201/7206 0.000130131911921 ko05133 Pertussis 12/286 87/7206 0.000149531216948 ko04640 Hematopoietic cell lineage 10/286 64/7206 0.000187487941913 ko05167 Kaposi's sarcoma-associated herpesvirus infection 19/286 191/7206 0.000192370238204 ko04940 Type I diabetes mellitus 7/286 32/7206 0.000206290668531 ko04630 Jak-STAT signaling pathway 15/286 132/7206 0.000215868072299 ko03050 Proteasome 9/286 54/7206 0.00023764699757 ko04064 NF-kappa B signaling pathway 12/286 96/7206 0.000382978865264 ko05310 Asthma 5/286 17/7206 0.000397001208621 ko05150 Staphylococcus aureus infection 7/286 36/7206 0.000446478335377 ko00120 Primary bile acid biosynthesis 5/286 20/7206 0.000901813812435 ko04610 Complement and coagulation cascades 10/286 79/7206 0.00105521102298 ko04660 T cell receptor signaling pathway 13/286 124/7206 0.00121430114506 ko05144 Malaria 7/286 45/7206 0.00178856034901 ko04622 RIG-I-like receptor signaling pathway 8/286 62/7206 0.00292544364395 ko00590 Arachidonic acid metabolism 7/286 52/7206 0.00416313869808 ko04137 Mitophagy - animal 9/286 82/7206 0.00496949252296 ko05416 Viral myocarditis 7/286 55/7206 0.00570838703389 ko00051 Fructose and mannose metabolism 6/286 42/7206 0.00583422531418 ko04611 Platelet activation 14/286 163/7206 0.00645379033844 ko04390 Hippo signaling pathway 1/286 188/7206 0.00717478605784 ko05323 Rheumatoid arthritis 9/286 89/7206 0.00847513971979 ko04080 Neuroactive ligand-receptor interaction 7/286 423/7206 0.00957653395213 ko04310 Wnt signaling pathway 1/286 181/7206 0.0105822695662 ko04664 Fc epsilon RI signaling pathway 8/286 77/7206 0.0109275582228 ko04728 Dopaminergic synapse 1/286 185/7206 0.0110708780487 ko03013 RNA transport 1/286 166/7206 0.0150163839518 ko05132 Salmonella infection 9/286 98/7206 0.0154210404634 ko05224 Breast cancer 1/286 174/7206 0.0158016348419 ko04723 Retrograde endocannabinoid signaling 1/286 175/7206 0.0160131825909 ko04514 Cell adhesion molecules (CAMs) 11/286 130/7206 0.0188982004883 ko05202 Transcriptional misregulation in cancer 14/286 188/7206 0.021162976684 ko04662 B cell receptor signaling pathway 8/286 88/7206 0.0230211270827 ko04360 Axon guidance 3/286 233/7206 0.0261171483245 ko04666 Fc gamma R-mediated phagocytosis 10/286 122/7206 0.0296313599269 ko03040 Spliceosome 1/286 145/7206 0.0312479046862 ko04110 Cell cycle 1/286 145/7206 0.0312479046862 ko00592 alpha-Linolenic acid metabolism 3/286 19/7206 0.0374327743912 ko05142 Chagas disease (American trypanosomiasis) 10/286 130/7206 0.0384089655784 ko05016 Huntington's disease 3/286 215/7206 0.0493103664507