ko pathway ratio_in_study ratio_in_pop p_value ko04015 Rap1 signaling pathway 5/15 278/7206 0.000180017135577 ko04014 Ras signaling pathway 5/15 279/7206 0.000183085023696 ko04910 Insulin signaling pathway 4/15 172/7206 0.000348254995736 ko04144 Endocytosis 5/15 342/7206 0.000473311821044 ko05214 Glioma 3/15 79/7206 0.000524824627625 ko05230 Central carbon metabolism in cancer 3/15 81/7206 0.000564827411803 ko04016 MAPK signaling pathway - plant 2/15 20/7206 0.000752035360665 ko01521 EGFR tyrosine kinase inhibitor resistance 3/15 106/7206 0.00123775966271 ko05215 Prostate cancer 3/15 111/7206 0.00141425546599 ko04915 Estrogen signaling pathway 3/15 131/7206 0.00227666189439 ko05200 Pathways in cancer 5/15 492/7206 0.00245839621899 ko04722 Neurotrophin signaling pathway 3/15 160/7206 0.00401668086215 ko04550 Signaling pathways regulating pluripotency of stem cells 3/15 165/7206 0.00438009222399 ko04068 FoxO signaling pathway 3/15 167/7206 0.00453091771409 ko04371 Apelin signaling pathway 3/15 177/7206 0.00533273589516 ko04218 Cellular senescence 3/15 177/7206 0.00533273589516 ko05213 Endometrial cancer 2/15 62/7206 0.00711639520208 ko04072 Phospholipase D signaling pathway 3/15 197/7206 0.00718251762682 ko05221 Acute myeloid leukemia 2/15 63/7206 0.00734090372672 ko05223 Non-small cell lung cancer 2/15 66/7206 0.00803361495082 ko04921 Oxytocin signaling pathway 3/15 209/7206 0.00845578710982 ko04370 VEGF signaling pathway 2/15 77/7206 0.0108150133433 ko04664 Fc epsilon RI signaling pathway 2/15 77/7206 0.0108150133433 ko05212 Pancreatic cancer 2/15 83/7206 0.0124879201383 ko05218 Melanoma 2/15 85/7206 0.0130693828182 ko05220 Chronic myeloid leukemia 2/15 85/7206 0.0130693828182 ko04213 Longevity regulating pathway - multiple species 2/15 86/7206 0.0133645283412 ko04917 Prolactin signaling pathway 2/15 87/7206 0.0136626009357 ko04662 B cell receptor signaling pathway 2/15 88/7206 0.0139635888512 ko05222 Small cell lung cancer 2/15 89/7206 0.0142674803683 ko04810 Regulation of actin cytoskeleton 3/15 264/7206 0.0159520594545 ko05211 Renal cell carcinoma 2/15 96/7206 0.0164750438045 ko04650 Natural killer cell mediated cytotoxicity 2/15 97/7206 0.0168017458886 ko04720 Long-term potentiation 2/15 99/7206 0.0174635371216 ko04620 Toll-like receptor signaling pathway 2/15 100/7206 0.0177986034666 ko04024 cAMP signaling pathway 3/15 279/7206 0.0184881436841 ko04012 ErbB signaling pathway 2/15 109/7206 0.0209372875098 ko04070 Phosphatidylinositol signaling system 2/15 112/7206 0.0220318771489 ko04912 GnRH signaling pathway 2/15 122/7206 0.0258498927687 ko04750 Inflammatory mediator regulation of TRP channels 2/15 122/7206 0.0258498927687 ko04211 Longevity regulating pathway 2/15 123/7206 0.0262457480551 ko04066 HIF-1 signaling pathway 2/15 123/7206 0.0262457480551 ko04660 T cell receptor signaling pathway 2/15 124/7206 0.0266441155564 ko01522 Endocrine resistance 2/15 124/7206 0.0266441155564 ko04010 MAPK signaling pathway 3/15 321/7206 0.0267464349925 ko04922 Glucagon signaling pathway 2/15 128/7206 0.0282624949513 ko05231 Choline metabolism in cancer 2/15 134/7206 0.0307636313209 ko04931 Insulin resistance 2/15 137/7206 0.0320466931315 ko04916 Melanogenesis 2/15 142/7206 0.0342323040046 ko04919 Thyroid hormone signaling pathway 2/15 143/7206 0.0346764103124 ko04626 Plant-pathogen interaction 1/15 18/7206 0.0368558490676 ko04270 Vascular smooth muscle contraction 2/15 154/7206 0.039711456622 ko04152 AMPK signaling pathway 2/15 161/7206 0.0430546795382 ko04071 Sphingolipid signaling pathway 2/15 162/7206 0.0435408665533 ko04151 PI3K-Akt signaling pathway 3/15 390/7206 0.0440502735374 ko04140 Autophagy - animal 2/15 164/7206 0.044519581813 ko05164 Influenza A 2/15 167/7206 0.0460033641942 ko05418 Fluid shear stress and atherosclerosis 2/15 173/7206 0.0490265431435 ko05161 Hepatitis B 2/15 173/7206 0.0490265431435 ko05224 Breast cancer 2/15 174/7206 0.0495375056786