ko pathway ratio_in_study ratio_in_pop p_value ko05340 Primary immunodeficiency 14/159 30/7206 3.90847991403e-16 ko04612 Antigen processing and presentation 18/159 77/7206 3.11562048559e-14 ko04060 Cytokine-cytokine receptor interaction 25/159 191/7206 3.55370191972e-13 ko05320 Autoimmune thyroid disease 11/159 29/7206 1.04868448271e-11 ko05330 Allograft rejection 10/159 24/7206 3.09973680254e-11 ko05168 Herpes simplex infection 22/159 182/7206 5.26484935963e-11 ko05164 Influenza A 21/159 167/7206 7.04838921124e-11 ko05152 Tuberculosis 22/159 187/7206 9.03099343394e-11 ko05332 Graft-versus-host disease 8/159 18/7206 1.70982625957e-09 ko04672 Intestinal immune network for IgA production 10/159 37/7206 4.30106288395e-09 ko05162 Measles 16/159 120/7206 6.35858801654e-09 ko04621 NOD-like receptor signaling pathway 18/159 157/7206 8.00626966386e-09 ko04640 Hematopoietic cell lineage 12/159 64/7206 1.07135138679e-08 ko05145 Toxoplasmosis 16/159 126/7206 1.30452612286e-08 ko05321 Inflammatory bowel disease (IBD) 11/159 56/7206 2.70011635291e-08 ko04620 Toll-like receptor signaling pathway 14/159 100/7206 3.13359945237e-08 ko04217 Necroptosis 18/159 178/7206 5.82925410199e-08 ko04659 Th17 cell differentiation 14/159 106/7206 6.68674217208e-08 ko05140 Leishmaniasis 12/159 75/7206 6.91105819085e-08 ko04940 Type I diabetes mellitus 8/159 32/7206 3.15952105418e-07 ko05310 Asthma 6/159 17/7206 1.06304912838e-06 ko04064 NF-kappa B signaling pathway 12/159 96/7206 1.10781404279e-06 ko04658 Th1 and Th2 cell differentiation 11/159 96/7206 7.47570201956e-06 ko04650 Natural killer cell mediated cytotoxicity 11/159 97/7206 8.27324494469e-06 ko05150 Staphylococcus aureus infection 7/159 36/7206 1.08731191742e-05 ko04145 Phagosome 14/159 162/7206 1.20005593242e-05 ko05133 Pertussis 10/159 87/7206 1.91470532148e-05 ko03050 Proteasome 8/159 54/7206 2.06947591565e-05 ko05416 Viral myocarditis 8/159 55/7206 2.37684513304e-05 ko05161 Hepatitis B 14/159 173/7206 2.5347267367e-05 ko04514 Cell adhesion molecules (CAMs) 12/159 130/7206 2.67572081473e-05 ko04062 Chemokine signaling pathway 15/159 201/7206 3.37097519584e-05 ko04380 Osteoclast differentiation 12/159 134/7206 3.62509855897e-05 ko04622 RIG-I-like receptor signaling pathway 8/159 62/7206 5.79071535208e-05 ko04660 T cell receptor signaling pathway 11/159 124/7206 8.42542401109e-05 ko05323 Rheumatoid arthritis 9/159 89/7206 0.00013896372784 ko04630 Jak-STAT signaling pathway 11/159 132/7206 0.000148164088572 ko05167 Kaposi's sarcoma-associated herpesvirus infection 13/159 191/7206 0.000287823863672 ko05144 Malaria 6/159 45/7206 0.000419679194526 ko04210 Apoptosis 11/159 180/7206 0.0020351448219 ko05142 Chagas disease (American trypanosomiasis) 9/159 130/7206 0.00223268335773 ko05146 Amoebiasis 7/159 99/7206 0.00608204677755 ko05166 HTLV-I infection 14/159 292/7206 0.00629382533106 ko05160 Hepatitis C 9/159 153/7206 0.00658002618595 ko04610 Complement and coagulation cascades 6/159 79/7206 0.00775036746507 ko04623 Cytosolic DNA-sensing pathway 4/159 41/7206 0.0122566959273 ko05322 Systemic lupus erythematosus 8/159 151/7206 0.0182935554047 ko04080 Neuroactive ligand-receptor interaction 3/159 423/7206 0.0254914510001 ko05143 African trypanosomiasis 3/159 32/7206 0.0327552840907 ko04668 TNF signaling pathway 6/159 120/7206 0.0491236390724 ko04142 Lysosome 7/159 151/7206 0.0491961091676