ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	162/903	423/7206	1.21500489693e-44
ko05033	Nicotine addiction	49/903	56/7206	1.92260641532e-37
ko04724	Glutamatergic synapse	83/903	152/7206	2.01600468583e-36
ko04727	GABAergic synapse	63/903	110/7206	2.01059882862e-29
ko05032	Morphine addiction	62/903	110/7206	1.97133655654e-28
ko04713	Circadian entrainment	63/903	136/7206	1.07154153078e-22
ko04723	Retrograde endocannabinoid signaling	72/903	175/7206	5.28570967775e-22
ko04728	Dopaminergic synapse	74/903	185/7206	1.04129668448e-21
ko04725	Cholinergic synapse	65/903	160/7206	1.31781657089e-19
ko04024	cAMP signaling pathway	88/903	279/7206	1.27674071664e-17
ko04911	Insulin secretion	48/903	117/7206	5.65106958042e-15
ko04721	Synaptic vesicle cycle	38/903	80/7206	1.34348161944e-14
ko04744	Phototransduction	24/903	36/7206	4.79764882497e-14
ko04742	Taste transduction	31/903	61/7206	3.75508013788e-13
ko04726	Serotonergic synapse	49/903	137/7206	1.4973951702e-12
ko04020	Calcium signaling pathway	75/903	265/7206	2.12139342123e-12
ko04261	Adrenergic signaling in cardiomyocytes	63/903	205/7206	3.25985837741e-12
ko04921	Oxytocin signaling pathway	61/903	209/7206	7.71754752442e-11
ko05031	Amphetamine addiction	35/903	91/7206	2.47889262114e-10
ko04720	Long-term potentiation	36/903	99/7206	8.58791833697e-10
ko04970	Salivary secretion	35/903	95/7206	9.80612893717e-10
ko05030	Cocaine addiction	29/903	73/7206	3.60370488637e-09
ko04971	Gastric acid secretion	34/903	98/7206	1.02766785141e-08
ko03040	Spliceosome	1/903	145/7206	1.48080085922e-07
ko04010	MAPK signaling pathway	73/903	321/7206	2.41985299534e-07
ko04925	Aldosterone synthesis and secretion	33/903	105/7206	2.52034937593e-07
ko05203	Viral carcinogenesis	10/903	277/7206	2.52923002571e-07
ko04972	Pancreatic secretion	33/903	111/7206	1.36021717443e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/903	74/7206	1.63064873932e-06
ko04060	Cytokine-cytokine receptor interaction	5/903	191/7206	2.01861915407e-06
ko04072	Phospholipase D signaling pathway	48/903	197/7206	3.31327040432e-06
ko05168	Herpes simplex infection	5/903	182/7206	4.04443314386e-06
ko04260	Cardiac muscle contraction	29/903	98/7206	7.03380050914e-06
ko04022	cGMP-PKG signaling pathway	50/903	216/7206	1.37820184918e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/903	79/7206	2.06606753018e-05
ko04514	Cell adhesion molecules (CAMs)	34/903	130/7206	2.11491101887e-05
ko04740	Olfactory transduction	24/903	80/7206	2.60770746116e-05
ko04360	Axon guidance	51/903	233/7206	4.75292079677e-05
ko05414	Dilated cardiomyopathy	29/903	112/7206	0.000123464893163
ko04915	Estrogen signaling pathway	32/903	131/7206	0.000149005225613
ko05322	Systemic lupus erythematosus	5/903	151/7206	0.00015015655138
ko04070	Phosphatidylinositol signaling system	28/903	112/7206	0.000249952808915
ko05164	Influenza A	7/903	167/7206	0.000336907980066
ko03013	RNA transport	7/903	166/7206	0.000337288210841
ko05205	Proteoglycans in cancer	16/903	271/7206	0.000350566343688
ko04730	Long-term depression	21/903	78/7206	0.000465001459203
ko04610	Complement and coagulation cascades	1/903	79/7206	0.000488638377387
ko04141	Protein processing in endoplasmic reticulum	9/903	184/7206	0.00064913904151
ko04612	Antigen processing and presentation	1/903	77/7206	0.000743785323369
ko04110	Cell cycle	6/903	145/7206	0.000865629154466
ko04350	TGF-beta signaling pathway	3/903	103/7206	0.00134212286641
ko04120	Ubiquitin mediated proteolysis	6/903	138/7206	0.00165810566545
ko04745	Phototransduction - fly	12/903	38/7206	0.00167271871734
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/903	59/7206	0.00223994839157
ko04540	Gap junction	28/903	128/7206	0.00272782007253
ko04014	Ras signaling pathway	52/903	279/7206	0.00299585564941
ko04621	NOD-like receptor signaling pathway	8/903	157/7206	0.00311637924836
ko03008	Ribosome biogenesis in eukaryotes	2/903	79/7206	0.00322620512819
ko04750	Inflammatory mediator regulation of TRP channels	27/903	122/7206	0.00330077590554
ko05034	Alcoholism	45/903	238/7206	0.00379649171969
ko04140	Autophagy - animal	9/903	164/7206	0.00392087678889
ko04973	Carbohydrate digestion and absorption	12/903	42/7206	0.0042540153504
ko05140	Leishmaniasis	2/903	75/7206	0.00466918515154
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/903	14/7206	0.00468216714212
ko04924	Renin secretion	20/903	86/7206	0.00488514530767
ko05169	Epstein-Barr virus infection	13/903	206/7206	0.00517117845015
ko04371	Apelin signaling pathway	35/903	177/7206	0.00546347745016
ko04976	Bile secretion	19/903	80/7206	0.00557343083069
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/903	182/7206	0.00609537211014
ko03018	RNA degradation	3/903	84/7206	0.00761672348368
ko04630	Jak-STAT signaling pathway	7/903	132/7206	0.00774313614444
ko05321	Inflammatory bowel disease (IBD)	1/903	56/7206	0.00783060602975
ko05162	Measles	6/903	120/7206	0.00802071180714
ko04064	NF-kappa B signaling pathway	4/903	96/7206	0.00804353568459
ko04923	Regulation of lipolysis in adipocytes	18/903	77/7206	0.00818418042153
ko00515	Mannose type O-glycan biosynthesis	8/903	25/7206	0.00897808015135
ko05161	Hepatitis B	11/903	173/7206	0.0102713624775
ko04137	Mitophagy - animal	3/903	82/7206	0.0108546066623
ko04015	Rap1 signaling pathway	49/903	278/7206	0.0122870122646
ko04142	Lysosome	9/903	151/7206	0.0122950942371
ko04918	Thyroid hormone synthesis	19/903	86/7206	0.0126664880705
ko05410	Hypertrophic cardiomyopathy (HCM)	21/903	100/7206	0.0144292789389
ko04930	Type II diabetes mellitus	13/903	54/7206	0.020150783384
ko04640	Hematopoietic cell lineage	2/903	64/7206	0.0206579515321
ko05016	Huntington's disease	16/903	215/7206	0.0209550964172
ko04964	Proximal tubule bicarbonate reclamation	8/903	29/7206	0.0226603166555
ko04062	Chemokine signaling pathway	36/903	201/7206	0.0231506837534
ko04150	mTOR signaling pathway	13/903	184/7206	0.0233553086821
ko00620	Pyruvate metabolism	1/903	46/7206	0.0251626907464
ko03420	Nucleotide excision repair	1/903	46/7206	0.0251626907464
ko00270	Cysteine and methionine metabolism	1/903	47/7206	0.025243209492
ko00260	Glycine, serine and threonine metabolism	1/903	48/7206	0.0257681284404
ko05219	Bladder cancer	1/903	48/7206	0.0257681284404
ko05145	Toxoplasmosis	8/903	126/7206	0.0300108250608
ko04214	Apoptosis - fly	3/903	72/7206	0.0300229196458
ko00310	Lysine degradation	3/903	73/7206	0.0306400527615
ko05202	Transcriptional misregulation in cancer	14/903	188/7206	0.0332846506294
ko05231	Choline metabolism in cancer	25/903	134/7206	0.0351186036757
ko00562	Inositol phosphate metabolism	18/903	89/7206	0.035136661148
ko00071	Fatty acid degradation	1/903	45/7206	0.0381713156464
ko04912	GnRH signaling pathway	23/903	122/7206	0.0384806781804
ko00480	Glutathione metabolism	2/903	55/7206	0.0407995458464
ko05131	Shigellosis	4/903	82/7206	0.0416395341857
ko04113	Meiosis - yeast	3/903	70/7206	0.043043748747
ko04670	Leukocyte transendothelial migration	11/903	151/7206	0.0469819758305