ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04610	Complement and coagulation cascades	36/506	79/7206	2.10679974828e-21
ko04974	Protein digestion and absorption	35/506	96/7206	4.60718530063e-17
ko04976	Bile secretion	23/506	80/7206	2.81118859997e-09
ko04978	Mineral absorption	14/506	40/7206	2.50936831111e-07
ko04977	Vitamin digestion and absorption	10/506	22/7206	7.99274812569e-07
ko04964	Proximal tubule bicarbonate reclamation	11/506	29/7206	1.98727974857e-06
ko04975	Fat digestion and absorption	12/506	35/7206	2.36540583612e-06
ko04512	ECM-receptor interaction	18/506	79/7206	6.25220892644e-06
ko00350	Tyrosine metabolism	11/506	33/7206	8.58421631985e-06
ko05150	Staphylococcus aureus infection	11/506	36/7206	2.19582524156e-05
ko05166	HTLV-I infection	5/506	292/7206	5.27051917107e-05
ko00983	Drug metabolism - other enzymes	11/506	42/7206	0.000106313504653
ko04614	Renin-angiotensin system	7/506	18/7206	0.000129914795354
ko04260	Cardiac muscle contraction	18/506	98/7206	0.00013352080698
ko03013	RNA transport	1/506	166/7206	0.000149627308025
ko04972	Pancreatic secretion	19/506	111/7206	0.000230378738397
ko00260	Glycine, serine and threonine metabolism	11/506	48/7206	0.000381814453579
ko05033	Nicotine addiction	12/506	56/7206	0.000406595147732
ko05169	Epstein-Barr virus infection	3/506	206/7206	0.000427030198821
ko04144	Endocytosis	9/506	342/7206	0.00045710676778
ko04973	Carbohydrate digestion and absorption	10/506	42/7206	0.000505711810092
ko04950	Maturity onset diabetes of the young	8/506	29/7206	0.000641957946678
ko05161	Hepatitis B	2/506	173/7206	0.000705688562878
ko03320	PPAR signaling pathway	13/506	69/7206	0.00087451008883
ko04550	Signaling pathways regulating pluripotency of stem cells	2/506	165/7206	0.000976005659679
ko04120	Ubiquitin mediated proteolysis	1/506	138/7206	0.00103760146112
ko00643	Styrene degradation	3/506	4/7206	0.00130517106952
ko05203	Viral carcinogenesis	7/506	277/7206	0.0016046726068
ko04310	Wnt signaling pathway	3/506	181/7206	0.00170283316271
ko04141	Protein processing in endoplasmic reticulum	3/506	184/7206	0.00177763994796
ko04062	Chemokine signaling pathway	4/506	201/7206	0.0019049265399
ko04660	T cell receptor signaling pathway	1/506	124/7206	0.00212931395931
ko05162	Measles	1/506	120/7206	0.00318706764439
ko04114	Oocyte meiosis	2/506	139/7206	0.00408271615644
ko04390	Hippo signaling pathway	4/506	188/7206	0.00530422742097
ko00980	Metabolism of xenobiotics by cytochrome P450	8/506	40/7206	0.00581096318432
ko04380	Osteoclast differentiation	2/506	134/7206	0.00582402203817
ko00340	Histidine metabolism	6/506	25/7206	0.00652566872803
ko04659	Th17 cell differentiation	1/506	106/7206	0.00660187310945
ko04621	NOD-like receptor signaling pathway	3/506	157/7206	0.0066551161183
ko00140	Steroid hormone biosynthesis	8/506	41/7206	0.00678779024403
ko00830	Retinol metabolism	8/506	42/7206	0.00788385668737
ko00040	Pentose and glucuronate interconversions	6/506	26/7206	0.00799138409423
ko05034	Alcoholism	7/506	238/7206	0.0093049276629
ko05016	Huntington's disease	6/506	215/7206	0.00961035257202
ko04072	Phospholipase D signaling pathway	5/506	197/7206	0.01003360218
ko04920	Adipocytokine signaling pathway	13/506	89/7206	0.0102743675282
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/506	79/7206	0.0116292462742
ko04740	Olfactory transduction	12/506	80/7206	0.0123006778194
ko00190	Oxidative phosphorylation	2/506	127/7206	0.0124247826805
ko04360	Axon guidance	7/506	233/7206	0.0124782375899
ko04727	GABAergic synapse	15/506	110/7206	0.0125477399495
ko00100	Steroid biosynthesis	5/506	21/7206	0.0132862032454
ko04514	Cell adhesion molecules (CAMs)	17/506	130/7206	0.0134555494875
ko04658	Th1 and Th2 cell differentiation	1/506	96/7206	0.0141214225501
ko00250	Alanine, aspartate and glutamate metabolism	7/506	38/7206	0.015151351966
ko00630	Glyoxylate and dicarboxylate metabolism	7/506	38/7206	0.015151351966
ko05410	Hypertrophic cardiomyopathy (HCM)	14/506	100/7206	0.0153542415782
ko00270	Cysteine and methionine metabolism	8/506	47/7206	0.0154512456001
ko00591	Linoleic acid metabolism	5/506	22/7206	0.0162260139523
ko00053	Ascorbate and aldarate metabolism	5/506	22/7206	0.0162260139523
ko01230	Biosynthesis of amino acids	12/506	85/7206	0.0169947858065
ko04668	TNF signaling pathway	2/506	120/7206	0.0172056474741
ko05204	Chemical carcinogenesis	8/506	48/7206	0.0174409358275
ko05168	Herpes simplex infection	5/506	182/7206	0.0179710236313
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/506	182/7206	0.0179710236313
ko04150	mTOR signaling pathway	5/506	184/7206	0.0181868484667
ko04924	Renin secretion	12/506	86/7206	0.0182191719007
ko04722	Neurotrophin signaling pathway	4/506	160/7206	0.0182552921159
ko04140	Autophagy - animal	4/506	164/7206	0.0188363156234
ko04662	B cell receptor signaling pathway	1/506	88/7206	0.0202670334066
ko04111	Cell cycle - yeast	1/506	90/7206	0.0204378347231
ko01200	Carbon metabolism	16/506	128/7206	0.0217407482559
ko04218	Cellular senescence	5/506	177/7206	0.0243001245411
ko04217	Necroptosis	5/506	178/7206	0.0244756636824
ko04630	Jak-STAT signaling pathway	3/506	132/7206	0.0248247081104
ko04911	Insulin secretion	15/506	117/7206	0.0257322870171
ko00360	Phenylalanine metabolism	4/506	17/7206	0.0274529452392
ko04510	Focal adhesion	26/506	240/7206	0.027679177689
ko05220	Chronic myeloid leukemia	1/506	85/7206	0.0298458160884
ko04060	Cytokine-cytokine receptor interaction	6/506	191/7206	0.0305033737889
ko04080	Neuroactive ligand-receptor interaction	41/506	423/7206	0.0307841159829
ko00410	beta-Alanine metabolism	6/506	35/7206	0.0330571554992
ko04914	Progesterone-mediated oocyte maturation	2/506	104/7206	0.0331543535582
ko01521	EGFR tyrosine kinase inhibitor resistance	2/506	106/7206	0.033332612112
ko04142	Lysosome	4/506	151/7206	0.0343754004669
ko04012	ErbB signaling pathway	2/506	109/7206	0.0345467338344
ko00130	Ubiquinone and other terpenoid-quinone biosynthesis	3/506	11/7206	0.0371546796665
ko00620	Pyruvate metabolism	7/506	46/7206	0.0397452674078
ko00982	Drug metabolism - cytochrome P450	6/506	37/7206	0.0421049972611
ko04370	VEGF signaling pathway	1/506	77/7206	0.0424341006773
ko04664	Fc epsilon RI signaling pathway	1/506	77/7206	0.0424341006773
ko00232	Caffeine metabolism	2/506	5/7206	0.0426842722334
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	2/506	5/7206	0.0426842722334
ko04071	Sphingolipid signaling pathway	5/506	162/7206	0.0431427437656
ko05164	Influenza A	5/506	167/7206	0.0441853960301
ko04620	Toll-like receptor signaling pathway	2/506	100/7206	0.0467295464113
ko00120	Primary bile acid biosynthesis	4/506	20/7206	0.0473483526286
ko04211	Longevity regulating pathway	3/506	123/7206	0.0476970170581
ko01522	Endocrine resistance	3/506	124/7206	0.0482076527849