ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 15/131 79/7206 7.00704437511e-12 ko04974 Protein digestion and absorption 12/131 96/7206 1.33970126163e-07 ko05205 Proteoglycans in cancer 17/131 271/7206 7.17497421869e-06 ko04512 ECM-receptor interaction 9/131 79/7206 1.156389264e-05 ko05200 Pathways in cancer 23/131 492/7206 2.1930391681e-05 ko05146 Amoebiasis 9/131 99/7206 7.16026964177e-05 ko04151 PI3K-Akt signaling pathway 19/131 390/7206 7.17794625283e-05 ko04510 Focal adhesion 14/131 240/7206 0.000107533435444 ko05222 Small cell lung cancer 8/131 89/7206 0.000197701499792 ko05224 Breast cancer 10/131 174/7206 0.00120721883766 ko05217 Basal cell carcinoma 6/131 68/7206 0.00140000982729 ko05219 Bladder cancer 5/131 48/7206 0.00168310182692 ko04390 Hippo signaling pathway 10/131 188/7206 0.00215513911046 ko04530 Tight junction 11/131 228/7206 0.00281541303798 ko05230 Central carbon metabolism in cancer 6/131 81/7206 0.00342662458823 ko05150 Staphylococcus aureus infection 4/131 36/7206 0.00391607525746 ko05206 MicroRNAs in cancer 9/131 177/7206 0.00481235017723 ko04978 Mineral absorption 4/131 40/7206 0.00574574817319 ko00340 Histidine metabolism 3/131 25/7206 0.0100816847796 ko00270 Cysteine and methionine metabolism 4/131 47/7206 0.0101730848286 ko04931 Insulin resistance 7/131 137/7206 0.012183794165 ko01521 EGFR tyrosine kinase inhibitor resistance 6/131 106/7206 0.0124808968387 ko04950 Maturity onset diabetes of the young 3/131 29/7206 0.0151957009115 ko05212 Pancreatic cancer 5/131 83/7206 0.0172551603065 ko04670 Leukocyte transendothelial migration 7/131 151/7206 0.0198562808779 ko05133 Pertussis 5/131 87/7206 0.0207420590802 ko05160 Hepatitis C 7/131 153/7206 0.021177546166 ko04920 Adipocytokine signaling pathway 5/131 89/7206 0.0226464684251 ko05120 Epithelial cell signaling in Helicobacter pylori infection 5/131 92/7206 0.0257102863713 ko00770 Pantothenate and CoA biosynthesis 2/131 14/7206 0.025872074751 ko05145 Toxoplasmosis 6/131 126/7206 0.0269271287348 ko04550 Signaling pathways regulating pluripotency of stem cells 7/131 165/7206 0.0304095466963 ko04514 Cell adhesion molecules (CAMs) 6/131 130/7206 0.0307656843241 ko04068 FoxO signaling pathway 7/131 167/7206 0.0321759160294 ko05020 Prion diseases 3/131 40/7206 0.0355866861484 ko04080 Neuroactive ligand-receptor interaction 2/131 423/7206 0.0357118707573 ko00660 C5-Branched dibasic acid metabolism 1/131 2/7206 0.0360305805774 ko04933 AGE-RAGE signaling pathway in diabetic complications 6/131 135/7206 0.0360472441375 ko00983 Drug metabolism - other enzymes 3/131 42/7206 0.0402894526738 ko04973 Carbohydrate digestion and absorption 3/131 42/7206 0.0402894526738 ko05166 HTLV-I infection 10/131 292/7206 0.0437232695173 ko04916 Melanogenesis 6/131 142/7206 0.0443728927499 ko00010 Glycolysis / Gluconeogenesis 4/131 74/7206 0.0452467341906 ko04115 p53 signaling pathway 4/131 74/7206 0.0452467341906 ko05140 Leishmaniasis 4/131 75/7206 0.0471479581746 ko05144 Malaria 3/131 45/7206 0.0479016328244 ko04012 ErbB signaling pathway 5/131 109/7206 0.0480169690703